The cell line development market was valued at US$ 6.86 billion in 2023 and is expected to reach US$ 18.62 billion by 2031. The market is expected to register a CAGR of 13.3% in 2023–2031. Ongoing advancements in cell line engineering and robust development in cell line technology will likely remain key cell line development market trends.
Developing cell lines is crucial for assessing toxicity, in-vitro testing, and the effectiveness of discovering new medications. This procedure lowers the chance of medication failure during clinical trials by saving money, time, and effort. Recombinant proteins are generated throughout the cell line development procedure. These include vaccines, fusion proteins, growth factors, enzymes, bi-specific and monoclonal antibodies, and novel approaches to creating immunotherapies for cancer treatment. Researchers seek ways to move through the early stages of biotherapeutic discovery and candidate selection to reduce the costs associated with cell line development. This process is efficient because it quickly produces and selects cell lines that yield high-quality recombinant protein in large quantities and removes clone candidates that are likely to fail as soon as feasible. Technological developments in cell line development have accelerated the testing of different drug candidates in the early phases of development, saving time and money.
Additionally, businesses engaged in drug discovery and cell line development have been cooperating, expanding the sector. For example, Cytiva recently purchased CEVEC Pharmaceuticals, a top German technology supplier for producing viral vectors and high-performance cell lines. Bio-Techne Corporation declared in July 2022 that Namocell, Inc. had been fully acquired. Simple single-cell sorting and dispensing platforms that protect cell viability and integrity are made available by the Namocell acquisition. In numerous workflows in biotherapeutics and diagnostics, such as developing and commercializing cell and gene therapies, cell engineering, cell line development, single-cell genomics, antibody discovery, synthetic biology, and rare cell isolation, Namocell's tools and consumables are essential technologies.
The process of choosing the cellular machinery to produce therapeutic biologics or other interesting proteins is called cell line development. Yeast, mammals, plants, and bacteria can use several expression systems to develop cell lines. Chinese hamster ovary (CHO) cells cultivated in suspension cultures are most frequently used to produce the complex protein. These cells are eventually used in bioreactors during the manufacturing stage. Small-scale suspension cultures are the first step in developing cell lines, eventually moving to large-scale bioreactors during manufacturing. The application of cell lines to generate therapeutic products transforms every aspect of the biopharmaceutical industry, from creating innovative gene therapies to producing state-of-the-art vaccines and cancer-fighting medications. This, in turn, creates significant opportunity in the market.
Many methods for producing large amounts of antigenic proteins have had to be developed in response to the increasing demand for vaccine products. Vaccine developers typically adhere to a linear process that includes thorough data analysis and verification to guard against historically high failure rates. Prominent producers of vaccines and antiviral medications are putting a lot of effort into creating new approaches to producing pandemic candidates and seasonal influenza vaccines. Until recently, most efforts have gone toward developing licensed egg-based vaccines. To meet the demands of the upcoming seasonal campaign and to produce pandemic vaccine prototypes for clinical trials, manufacturers have been focusing on increasing production capacities and automating parts of largely manual steps in egg-based vaccine technology. Thus, an increase in the production of vaccines is likely to drive the growth of the cell line development market.
Cell lines are needed for production because biologics and biosimilars are receiving more attention. Research and development opportunities in this field can be made possible through partnerships with government initiatives, biotech companies, and academic institutions. Furthermore, India is desirable for cell line development activities due to its highly skilled workforce and cheaper development costs than Western nations. For instance, through national funding organizations like the Department of Biotechnology (DBT), the Indian Council of Medical Research (ICMR), and the Department of Science and Technology (DST), the government supports the development of cell lines in developing nations like India.
Key segments contributing to the cell line development market analysis derivation are type, product, and application.
The cell line development market report's geographic scope is divided into five regions: North America, Asia Pacific, Europe, Middle East & Africa, and South America/South & Central America.
North America has dominated the cell line development market. In North America, the US is the largest market for cell line development in 2023. The expansion of the US cell line development market is attributed to the different players in the industry, and the dynamic conditions established in this area have changed the dynamics of cell line development in the area. Key players in the market, a lot of research and development being done by different academic and research institutes, and a growing demand for novel products from biopharmaceutical and biotechnology companies are growth characteristics in North America. Furthermore, significant funding for genomic research from public and private entities, along with growing emphasis on the integration of advanced methods in healthcare and government and private initiatives to promote precision medicine, are anticipated to propel growth and generate exceptional revenue for the North American cell line development market. Due to numerous development initiatives and business plans that support the creation, discovery, or modification of diverse biomolecules and organisms through bioengineering techniques, medical biotechnology has experienced revolutions. The nation's new businesses with exciting and creative ideas have benefited from the Biotech Startup Revolution, which has also helped maximize revenue generation and North America's economic standing in the international cell line development market.
The regional trends and factors influencing the Cell Line Development Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Cell Line Development Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.
| Report Attribute | Details |
|---|---|
| Market size in 2023 | US$ 6.86 Billion |
| Market Size by 2031 | US$ 18.62 Billion |
| Global CAGR (2023 - 2031) | 13.3% |
| Historical Data | 2021-2022 |
| Forecast period | 2023-2031 |
| Segments Covered |
By Type
|
| Regions and Countries Covered | North America
|
| Market leaders and key company profiles |
The Cell Line Development Market market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.
Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.
Major Companies operating in the Cell Line Development Market are:
Disclaimer: The companies listed above are not ranked in any particular order.
The cell line development market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. The following is a list of developments in the market for cell line development and strategies:
The “Cell Line Development Market Size and Forecast (2021–2031)” report provides a detailed analysis of the market covering below areas: