A brain aneurysm or cerebral aneurysm is the development of a bulge in the brain's blood vessels. The bulge puts pressure on the nerves or brain tissues, and rupture or burst can cause brain bleeding, which can be fatal to a patient. Factors such as genetic conditions, arteriovenous malformations, untreated high blood pressure, and smoking cause brain aneurysms. Microsurgical clipping is the more established method of treating aneurysms. The first aneurysm ever treated by surgical clipping was performed at Johns Hopkins Hospital on March 23, 1937. During microsurgical clipping, a small metal clip is used to stop blood flow into the aneurysm. A craniotomy is performed to create an opening in the skull to reach the aneurysm. The clip is placed on the neck (opening) of the aneurysm to obstruct the flow of blood and it is left inside the brain after the procedures.
The report offers insights and in-depth analysis of the global cerebral aneurysm clips market, emphasizing various parameters including market trends, technological advancements, market dynamics, and competitive landscape analysis of global leading market players. It also includes the impact of the COVID-19 pandemic on the market across all major regions. The cerebral aneurysm clips market experienced the overall mixed impact of the COVID-19 pandemic, and hence, the market is still gaining traction and is expected to grow in the coming years. During this health emergency, delivering medical care to all patients became challenging for healthcare systems, which were overburdened due to the need to treat the vast number of COVID patients. Medical device companies also faced issues in managing their operations in 2020. However, with gradual relaxation in social restrictions and the resumption of elective procedures by hospitals, the demand for surgical procedures and related accessories has returned to normal levels.
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Cerebral Aneurysm Clips Market: Strategic Insights
By geography, the cerebral aneurysm clips market is segmented into North America (US, Canada, and Mexico), Europe (France, Germany, UK, Spain, Russia, Italy, and Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, Kazakhstan, and Rest of Asia Pacific), the Middle East & Africa (Saudi Arabia, the UAE, South Africa, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).
Cerebral aneurysms are common among the elderly populations, making the need for noninvasive vascular imaging more evident. Inconsistencies in life expectancy, cognitive dysfunction, vasculopathy, comorbidities, and rupture risks associated with heterogenous endovascular and surgical treatments contribute to a surge in the use of cerebral aneurysm clips. As per a research study conducted at the University of Maryland School of Medicine in 2021, the proportion of individuals aged 65 or above will reach 21% by 2050 from 8.1%. Several autopsy studies have correlated the increased prevalence of unruptured cerebral aneurysms with advancing age. Inagawa et al. from Shimane Prefectural Central Hospital, Izumo, Japan, examined 10,259 autopsies performed in New York. They found the incidence of unruptured cerebral aneurysms highest in patients aged 60 and above, with a peak prevalence of 1.2% in people aged 70 and above. Iwamoto et al., Kyushu University, Fukuoka, Japan, assessed 1,230 autopsies in Japan, reporting an overall increased prevalence of unruptured aneurysms with advancing age in women, with a peak prevalence of 14.5% in Japanese women of age 60–69 years. When reviewing magnetic resonance angiography studies in 8,696 asymptomatic Japanese adults, Harada et al. identified unruptured cerebral aneurysms in 3.2% of cases, and the prevalence increased with age in both men and women.
Many potential studies have assessed the occurrence of aneurysm rupture and its connection with old age. The overall risk of rupture per patient-year risk in the general population is 0.6–1.3%. Additional pertinent risk factors include a history of subarachnoid hemorrhage (SAH), hypertension, smoking, multiple aneurysms, and irregular morphology in the geriatric population. Some studies state that aneurysm size may be related to patient age. The Unruptured Cerebral Aneurysm Study of Japan (UCAS Japan) evaluated 6,697 cerebral aneurysms; 39.7% of patients aged 80 years and above had a size of 7 mm, or larger aneurysms were found in 21.4% of patients of age 50–59 years. Therefore, the ideal management of cerebral aneurysms in elderly patients provides scope for further developments and advanced care. Management is currently individualized, requiring the precise knowledge of natural history and risk of rupture that must be weighed against an individual's comorbidities, life expectancy, treatment-related risks, and success possibilities. Thus, with the growing elderly population, having a greater prevalence of aneurysms, companies in the cerebral aneurysms market are likely to grab significant growth opportunities in the coming years.
Based on material type, the cerebral aneurysm clips market is segmented into pure titanium and titanium-based alloys, cobalt–chromium-based alloys, phynox, and others. In 2021, the pure titanium and titanium-based alloys segment is anticipated to hold the largest market share, however, the phynox segment is anticipated to register the highest CAGR in the market from 2022 to 2028.
The regional trends and factors influencing the Cerebral Aneurysm Clips Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Cerebral Aneurysm Clips Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.
| Report Attribute | Details |
|---|---|
| Market size in 2021 | US$ 53.81 Million |
| Market Size by 2028 | US$ 81.96 Million |
| Global CAGR (2021 - 2028) | 6.3% |
| Historical Data | 2019-2020 |
| Forecast period | 2022-2028 |
| Segments Covered |
By Material Type
|
| Regions and Countries Covered | North America
|
| Market leaders and key company profiles |
The Cerebral Aneurysm Clips Market market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.
Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.
Major Companies operating in the Cerebral Aneurysm Clips Market are:
Disclaimer: The companies listed above are not ranked in any particular order.
Based on indication, the cerebral aneurysm clips market is segmented into saccular aneurysm, fusiform aneurysm, and mycotic aneurysm. The saccular aneurysm segment held the largest market share in 2021; however, the mycotic aneurysm segment is anticipated to register the highest CAGR in the market from 2022 to 2028.
Based on end user, the cerebral aneurysm clips market is segmented into hospitals, neurology centers, ambulatory surgical centres, and others. The hospitals segment held the largest market share in 2021; however, the neurology center segment is estimated to register the highest CAGR in the market from 2022 to 2028.
The cerebral aneurysm clips market players take up organic strategies, including product launch and expansion, to expand their footprint and product portfolio worldwide. Key players in the market are B. Braun Melsungen AG; Peter Lazic GmbH; Mizuho Medical Co. Ltd; Rebstock Instruments GmbH; KLS Martin Group; Integra Lifesciences Corporation; Ortho-Medical GmbH; and Adeor Medical AG.
Global cerebral aneurysm clip market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America. In North America, the U.S. is the largest market for cerebral aneurysm clips market. The US is estimated to hold the largest share in the cerebral aneurysm clips market during the forecast period. The presence of top players and favorable regulations related to product approvals coupled with the commercialization of new products are the contributing factors to the regional growth. Additionally, the increasing number of technological advancements is the key factor responsible for the Asia-Pacific regional growth for cerebral aneurysm clips accounting fastest growth of the region during the coming years.
The Global cerebral aneurysm clips market, including B. Braun Melsungen AG; Peter Lazic GmbH; Mizuho Medical Co. Ltd; Rebstock Instruments GmbH; KLS Martin Group; Integra Lifesciences Corporation; Ortho-Medical GmbH; Adeor Medical AG and among others.
The Unruptured aneurysm segment dominated the global cerebral aneurysm clip market and accounted for the largest revenue of 47.8 Mn in 2021.
Based on Indication, saccular aneurysm accounts for the largest share in 2021 and is expected to continue to do so till the forecast period.
The more established method of treating aneurysms is microsurgical clipping. The first aneurysm ever treated by surgical clipping was performed at Johns Hopkins Hospital by Dr Walter Dandy on March 23, 1937. During microsurgical clipping, a small metal clip is used to stop blood flow into the aneurysm. A craniotomy is performed to create an opening in the skull to reach the aneurysm in the brain. The clip is placed on the neck (opening) of the aneurysm to obstruct the flow of blood and remains inside the brain.
Increasing prevalence of brain aneurysms and the rise in research and development activities is one of the most significant factors responsible for the overall market growth.