The long read sequencing is a DNA sequencing technique. It offers numerous distinct advantages than next-generation sequencing technologies such as more precisely sequence DNA containing the same sections of DNA repeated within the genome. Many adults aged 60 years and above suffer from two or more chronic illnesses. Genes play a role in chronic diseases such as cardiovascular disease, diabetes, obesity, RA, Alzheimer's disease (AD), and depression, according to twin research. According to the Centers for Disease Control and Prevention (CDC), about 6 out of 10 individuals in the US are affected by at least one chronic disease, as well as 4 out of 10 are suffering from two or more chronic diseases. Furthermore, cancer is primarily caused by genomic errors. Researchers have analyzed cancer genomes using a variety of rapidly evolving sequencing technologies in order to better understand cancer cells' molecular status and expose their vulnerabilities such as driver mutations or gene expression. The researchers were able to recognize and classify new forms of cancerous mutations using long-read technologies, including complex structural variants in haplotype resolution. In recent years, several long read sequencing technologies have been developed and used. For example, Pacific Biosciences developed SMRT sequencing, which is one of the long read methods (PacBio). Long read sequencing is becoming more common, and cancer studies based on long read data are growing and advancing in order to decode complex cancer genomes.
Long-read technologies are overcoming early limitations of accuracy and throughput and mounting their application in the fields of genomics. Long read sequencing or third-generation sequencing offers several advantages over short-read sequencing. While short-read sequencers such as Illumina’s HiSeq, NovaSeq, NextSeq, and MiSeq instruments, BGI’s MGISEQ and BGISEQ models; or Thermo Fisher’s Ion Torrent sequencers produce reads of up to 600 bases, long read sequencing technologies regularly generate reads over 10 kb Further, long reads can improve de novo assembly, mapping certainty, transcript isoform identification, and detection of structural variants. Also, long read sequencing of native molecules, i.e., DNA and RNA eliminates amplification bias while preserving base modifications. With continuing progress in accuracy, throughput, and cost reduction, these capabilities have begun to make long read sequencing an option for a broad range of applications in genomics for model and non-model organisms.
The regional trends and factors influencing the Long Read Sequencing Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Long Read Sequencing Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.
| Report Attribute | Details |
|---|---|
| Market size in 2020 | US$ 1.1 Billion |
| Market Size by 2028 | US$ 5.33 Billion |
| Global CAGR (2020 - 2028) | 22.3% |
| Historical Data | 2018-2019 |
| Forecast period | 2021-2028 |
| Segments Covered |
By Technology
|
| Regions and Countries Covered | North America
|
| Market leaders and key company profiles |
The Long Read Sequencing Market market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.
Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.
Major Companies operating in the Long Read Sequencing Market are:
Disclaimer: The companies listed above are not ranked in any particular order.
The List of Companies - Long Read Sequencing Market
The dearth of skilled professionals is the significant factor that will hinder the long read sequencing market growth.
The global long read sequencing market is being driven by factors such as advantages of long read sequencing and increasing prevalence of chronic diseases are likely to offer significant opportunities for the growth of the global long read sequencing market.
Oxford Nanopore Technologies; Tataa Biocenter; Illumina, Inc; Perkinelmer Inc.; F. Hoffmann-La Roche Ltd.; and among others are major companies operating in this market.