Native antigens are extracted in their natural form from the respective sources. As they undergo usual modifications in vivo, upon isolation, they exhibit close resemblance withthe complex 3-dimensional structure they exhibit in the host. In the case of protein antigens, these modifications may include post-translational alterations such as cleavage of precursor proteins, formation of disulphide bonds, and addition of low molecular weight groups through processes such as glycosylation or phosphorylation. The global native bacterial and viral antigens market is driven by factors such as increasing use of native microbial antigens in diagnostics and therapeutics, and rising prevalence of infectious diseases. However, the limitations associated with native antigens such as high cost, low antigen production levels, and scale-up difficultieshinder the market growth.However, emerging markets are creating growth opportunities for the market players.
Antigens are the biomolecules that are capable of triggering immune response in host body through the activation of lymphocytes. Bacterial antigens are used in the development of various types of antibodies in research laboratories for the improvement of immune systems. Moreover, bacterial antigens are also widely used in immunodiagnostic assays such as ELISA.
Panning of native antigen libraries have led to development of potent neutralization antibodies against various bacterial and viral infections. The native antigens are extracted in their natural form from a corresponding source. There is high demand for a large number of native antigens, especially in in vitro diagnostics and vaccine research. According to various scientific studies, recombinant antigens exhibit solubility and aggregation issues. Further, the association of recombinant antigens with non-protein entities is also different and sometimes lacking in terms of performance as compared to native antigens.
With the recent outbreak of COVID-19, companies are developing commercial SARS-CoV-2 antigens to support the vaccine formulation, and research and development to strengthen the disease diagnosis and therapy. In February 2020, the Native Antigen Company became the first company to commercially provide the novel coronavirus antigens, using the company’s proprietary VirtuE (HEK293) expression system. Thus, the rising use of native antigens, effectively supporting the diagnostics and therapeutics of various medical conditions, boosts the growth of the native bacterial antigen and antibody market.
The native bacterial and viral antigens market,based on product type, is segmented into chlamydia antigens, adenovirus antigens, borrelia antigens, clostridium antigens, chikungunya virus antigens, and dengue virus antigens. The chlamydia antigens segment held the largest share of the market in 2019, and the market for the same is anticipated to grow at the highest CAGR during the forecast period. Growth of the market for this segment is attributed to easy availability of these antigens, with majority of the market players commercially offering these antigens in the native forms. Further, the use of chlamydiaantigens in research institutes and laboratories for the development of vaccines and in vitro diagnostics (IVD) tests is further expected to propel the growth of the market for this segment.
Based on pathogen type, the native bacterial and viral antigens market is segmented into inactivated pathogen and purified pathogen. The inactivated pathogen segment held a larger share of the market in 2019, and it is estimated to register a higher CAGR during the forecast period.
Based on application, the native bacterial and viral antigens market is segmented into ELISA, immunoassay, SDS-PAGE, hemagglutination, and agglutination tests. The ELISA segment held the largest share of the market in 2019 and is estimated to register the highest CAGR during 2020–2027.
Based on end user, the native bacterial and viral antigens market is segmented into diagnostic laboratories and centers and academic and research institutes. The diagnostic laboratories and centers segment held the largest share of the market in 2019, and it is estimated to register the highest CAGR from 2020 to 2027.
Product launches and approvalsare the commonly adopted strategies by companies to expand their global footprintsand product portfolios; these strategies help them meet the growing consumer demand. Collaboration is one of the major strategies adopted by the companies operating in the native bacterial and viral antigens market to enlarge customer base worldwide, which also permits them to maintain their brand name globally.
The regional trends and factors influencing the Native Bacterial and Viral Antigens Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Native Bacterial and Viral Antigens Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.
| Report Attribute | Details |
|---|---|
| Market size in 2019 | US$ 17.11 Million |
| Market Size by 2027 | US$ 28.8 Million |
| Global CAGR (2019 - 2027) | 6.8% |
| Historical Data | 2017-2018 |
| Forecast period | 2020-2027 |
| Segments Covered |
By Product Type
|
| Regions and Countries Covered | North America
|
| Market leaders and key company profiles |
The Native Bacterial and Viral Antigens Market market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.
Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.
Major Companies operating in the Native Bacterial and Viral Antigens Market are:
Disclaimer: The companies listed above are not ranked in any particular order.
The List of Companies - Native Bacterial and Viral Antigens Market
The native bacterial and viral antigensmarket majorly consists of the players such as BIO-RAD LABORATORIES, INC., Microbix Biosystems, SERION Immunologics, Aalto Bio Reagents Ltd., Enzo Life Sciences, Inc., Jena Bioscience GmbH, ROSS SOUTHERN LABORATORIES, The Native Antigen Company, Creative Diagnostics, and TRINA BIOREACTIVES AG amongst others.
Factors such as increasing use of native microbial antigens in diagnostics and therapeutics, and rising prevalence of infectious diseases drive the growth of the market.Moreover, developments in emerging markets is expected to offer lucrative opportunities for the growth of the market.
Native antigens are extracted in their natural form from an appropriate source. Because they have undergone the usual modifications that would occur in vivo, they bear a very close resemblance when isolated to the complex 3-dimensional structure they exhibit in the host. In the case of protein antigens, these modifications can include post-translational alterations such as cleavage of precursor proteins, formation of disulphide bonds, and addition of low molecular weight groups through processes such as glycosylation or phosphorylation.