対象となる抗生物質市場 - 2031 年の成長予測、統計および事実

  • Report Code : TIPRE00026607
  • Category : Life Sciences
  • No. of Pages : 125
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抗生物質は現代医学の基礎要素であり、感染症の負担を軽減し、死亡率を減らし、さらには抑制するという実績があります。原因となる病原体を特定する必要なく、感染症を迅速に治療できることにより、感染症の蔓延が抑制され、手術、臓器移植、化学療法、新生児および小児ケアなどの現代医療にいくつかの機会が開かれました。しかし、そのような利点はすべて、前述の利点やさらに多くの利点を台無しにしており、WHOはポスト抗生物質時代の可能性とそれに伴う抗生物質耐性の負担について警告しています。抗生物質耐性が継続するため、2050 年までに抗生物質耐性感染症による年間死者数は 1,000 万人を超え、世界経済のコスト負担は最大 100 兆ドルに達すると予想されています。

抗生物質耐性の管理と封じ込めは、臨床、規制、経済の多面的なアプローチです。そのような措置は、規制枠組みの改善、パイプラインの増強、新しい狭スペクトル抗生物質および代替療法の開発、治療目標の変更、標的抗生物質開発の奨励に至るまで多岐にわたります。抗菌戦略の主な側面は、標的を絞った抗生物質、つまり種または属に特異的な抗菌薬の開発と商品化です。この研究では、このアプローチの課題と利点について議論し、狭い範囲の抗生物質と標的を絞った抗生物質の同定に向けて役立ついくつかの推奨事項に焦点を当てています。このレビューは、レビューや市場動向を包括的にまとめたものではありませんが、標的抗生物質の分野における最近の進歩と普及動向のハイライトとして使用することを目的としています。

耐性菌感染症と戦うための有望な戦略は、感染とその結果として生じる耐性菌のリスクを予防し、抗生物質パイプラインを改修することです。経済的手段と規制的手段を組み合わせて、利用可能な抗生物質の使用を維持することで耐性のリスクを遅らせ、耐性感染症の可能性を減らすための微生物攻撃治療の新しいアプローチを開発し、種特異的で狭いスペクトルの抗生物質を開発し、微生物因子よりも宿主を標的とします。

現在利用可能な抗生物質の有用性を高めるための使用計画の改善は、確かに効果的です。抵抗のリスクを封じ込める最善の戦略ですが、明確に定義された追跡メカニズムと均一なリソースの欠如が、このアプローチの可能性を妨げています。別のアプローチは、標的を絞ったアプローチとして新しい抗生物質を開発することです。これにより、原因となる病原体を攻撃し、微生物叢への影響を軽減、または最小限に抑えることができます。 スペクトル抗生物質は一般化された粗雑なアプローチであると見なされることが多く、これらの薬剤は原因となる病原体に対処するだけでなく、他のマイクロバイオームに目に見える損傷を引き起こすこともあります。したがって、そのような非標的治療は、最終的な疾患の発症という点で重大な結果をもたらす可能性があり、そのため新世代の抗生物質の必要性が高まり、最終的にはこれらの懸念に対処するための移行が必要となります。最近臨床開発の後期段階に達したいくつかの潜在的な候補(標的病原体特異的抗生物質)には、リジニラゾール、アファビシン、AR-101 などがあります。耐性菌の治療法となる可能性のある前臨床候補がいくつかあります。

抗生物質の研究開発パイプラインの目に見える崩壊は、次のように考えられています。これは経済的および規制上の課題の結果である可能性があり、それについてはこのレポートでさらに詳しく説明します。これらの課題を克服する解決策は、抗生物質開発に対する規制と経済的アプローチをより適切に調整し調整することであることが推奨されています。官民パートナーシップ (PPP) は、研究開発の焦点を満たされていないニーズに合わせるための潜在的なステップとなる可能性があります。

新規の規制の見通しと人口限定抗生物質薬などのそれぞれのアプローチ米国感染症学会の取り組みにより、耐性の高い病原体によって引き起こされる特定の感染症に焦点を当てた、小規模で安価な臨床試験に対応する医薬品の承認も可能になります。したがって、このような取り組みは、臨床医による抗生物質の所有を強化し、臨床試験のコストを削減することで金銭的なインセンティブを提供するために推奨されています。このレポートは、広範囲および狭いスペクトルの抗生物質市場全体の現在および将来の状況を包括的に説明します。この研究はまた、標的抗生物質の開発において政府、臨床医、製薬メーカーによって開発および展開されている主要な戦略を垣間見ることができます。この研究は、さらなる抗生物質耐性のリスクを軽減するために講じられた措置と、この分野で講じることができる経済的、規制的、臨床的アプローチの観点からの分析的推奨事項で締めくくられています。

  • Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
  • PEST and SWOT Analysis
  • Market Size Value / Volume - Global, Regional, Country
  • Industry and Competitive Landscape
  • Excel Dataset
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

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to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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to country scope.

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The List of Companies

  1. GlaxoSmithKline PLC
  2. Pfizer Inc.
  3. Johnson & Johnson Inc.
  4. Merck & Co. Inc.
  5. Bayer AG
  6. Novartis AG
  7. Sanofi SA
  8. F. Hoffmann La Roche AG
  9. Eli Lilly & Company
  10. Otsuka Pharmaceutical Co. Ltd.
  11. AbbVie
  12. STADA Arzneimittel
  13. Cubist Pharmaceuticals
  14. Abbott Laboratories
  15. Shionogi & Co., Ltd.
  16. Daiichi Sankyo
  17. Astellas Pharma
  18. Sun Pharmaceutical Industries
  19. Lupin
  20. Cipla
  21. Top Antibiotic Startups
    1. Arixia Pharmaceuticals
    2. Acurx Pharmaceuticals
    3. Clemedi
    4. Locus Biosciences
    5. Bioversys
    6. Paratek Pharma
    7. Destiny Pharma
    8. Vedanta Biosciences
    9. Spero Therapeutics
    10. Oxford Drug Designs
    11. Entasis Therapeutics
    12. Nabriva
    13. Melinta Therapeutics

 


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The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.