Genotyping Market Dynamics, Recent Developments, and Strategic Insights by 2031

The genotyping market size is projected to reach US$ 154.35 billion by 2031 from US$ 30.44 billion in 2023. The market is expected to register a CAGR of 22.5% during 2023–2031. A diverse range of applications of genotyping, including personalized medicine, agriculture, and animal breeding, owing to growing awareness efforts and campaigns would continue to be key trends in the market.

Genotyping Market Analysis

The development of high-throughput genotyping technologies as next-generation sequencing and microarray analysis has benefitted the genotyping market. The subsequently increasing use of genotyping in agriculture and animal breeding to improve crop yields, develop disease-resistant crops, and enhance livestock production is one of the key drivers for the genotyping market growth. The ongoing R&D activities in genomics, genetics, and related fields, leading to the discovery of new genetic markers and associations with diseases, are also contributing to the market progress.

Genotyping Market Overview

India has a relatively high prevalence of genetic disorders due to its vast population, high birth rate, and the preference for consanguineous marriage in some communities. Research and development (R&D) work is being carried out on human genetics, genome analysis, and precision medicine to potentially reduce the burden of such diseases by comprehending the mutation spectrum of diseases. These R&D programs are focused on implementing prenatal and newborn screening programs, developing cost-effective diagnostic methods for genetic diseases and affordable therapies for these diseases, and creating personalized medicine regimens.

Genetic disorders such as cancer are prevalent in India. According to the WHO, ~1.41 million people in India were suffering from cancer in 2022. The article titled "Breast Cancer Survival in India Across 11 Geographic Areas Under the National Cancer Registry Programme" lists breast cancer as the most common cancer in the country, as it accounts for ~28.2% of all cancer cases in females; ~ 216,108 breast cancer cases were reported in women in 2022.

Major programs and initiatives in the genomic research in India are mentioned below:

• DBT – Unique Methods of Management of Inherited Disorders (UMMID) Initiative
• GenomeIndia
• Human Microbiome Initiative of select endogamous populations of India
• Program on Monogenic disorders
• National Genomics Core

Thus, a surging number of programs and initiatives in genomic research would offer significant opportunities for the genotyping market growth in India in the coming years.

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Genotyping Market: Strategic Insights

Genotyping Market

• 
  CAGR (2023 - 2031)

  22.5%
• Market Size 2023
  US$ 30.44 Billion
• Market Size 2031
  US$ 154.35 Billion

Market Dynamics

GROWTH DRIVERS

• Use in Diagnosis of Genetic and Rare Diseases

FUTURE TRENDS

• Increasing Popularity of Personalized Medicine

OPPORTUNITIES

• Expanding Range of Applications

Key Players

• F Hoffmann La Roche Ltd
• QIAGEN NV
• Merck KGaA
• Eurofins Genomics
• Thermo Fisher Scientific Inc
• BioTek Instruments Inc
• Xcelris
• Trimgen Corporation I
• llumina Inc
• Danaher Corp

Regional Overview

• North America
• Europe
• Asia-Pacific
• South and Central America
• Middle East and Africa

Market Segmentation

Product Type

• Instruments
• Reagents and Kits
• Bioinformatics
• Genotyping Services

Technology

• Microarray
• Capillary Electrophoresis
• Sequencing
• Polymerase Chain Reaction
• Matrix-Assisted Laser Desorption/MALDI-TOF
• Other Technologies

Application

• Pharmacogenomics
• Diagnostics and Personalized Medicine
• Animal Genetics
• Agricultural Biotechnology
• Other Applications

End User

• Pharmaceutical and Biopharmaceutical Companies
• Diagnostic and Research Laboratories
• Academic Institutes
• Other End Users

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Genotyping Market Drivers and Opportunities

Use in Diagnosis of Genetic and Rare Diseases to Favor Market

According to the World Health Organization (WHO), ~35 million new cancer cases are likely to occur by 2050, a 77% increase from the corresponding 20 million cases in 2022. In 2022, the Alzheimer's Association stated that the number of people living with Alzheimer's in the US is rapidly increasing. The disease affects more than 6 million Americans from all age groups. As per the association's estimates, 6.5 million Americans aged more than 65 suffered from Alzheimer's as of 2022, and 73% of this population was aged 75 or older. As per a study published in the Journal of Health Monitoring, up to 300 million people worldwide suffer from rare diseases. Although individual diseases are rare, they collectively pose significant challenges to the global healthcare system.

Since cancer, Alzheimer's disease, and rare diseases are challenging to identify clinically, genotyping stands as the backbone of diagnostic testing in the population. DNA sequences obtained from genotyping can be compared to sample or reference sequences to determine variations. Genotyping is also employed to detect single-nucleotide polymorphisms (SNPs), which are minor variations in genetic complement within the population. The human genome has nearly 660 million SNPs, which makes them the most widespread genetic variation. Moreover, by comparing polymorphisms in healthy and diseased populations, genome-wide association studies (GWAS) can uncover links between common illnesses and SNPs. GWAS can untangle the molecular mechanisms in underlying disease states by finding probable causes. SNPs are even present in single-celled organisms, such as bacteria. SNP genotyping can differentiate between microbial isolates and could even be accustomed to identifying antibiotic-resistant strains. SNP-based strain detection has a significant impact on each pharmaceutical and clinical analysis, and it has also been used in infectious disease epidemiology.

Thus, the use of genotyping techniques in the diagnosis of genetic and rare diseases bolsters the genotyping market.

Expanding Range of Applications to Offer Opportunity for Market

Genotyping holds potential applications in diagnostic research, pharmacogenomics, and agricultural biotechnology. Moreover, this technique is suitable for a variety of plant breeding, forensic, and environmental testing procedures. Pharmaceutical companies are profiting from the availability of polygenic risk scores, substantial genetic databases linked to patient health information, and the sequencing data of clinical trial participants, among other advancements. The Industry Pharmacogenomics Working Group (I-PWG), an association of pharmaceutical companies, is actively involved in pharmacogenomic research. The I-PWG comprises 26 member companies that undertake numerous clinical trials annually, collecting DNA samples of study subjects as part of the protocol. With its focus on clinical pharmacogenomics, the I-PWG aims to generate opportunities for pharmaceutical companies in the coming years. In addition to its most frequent use in oncology research, clinical pharmacogenomics is also used for PGx studies conducted in non-oncology therapeutic areas such as rare diseases, immunology, and cardiology. A more comprehensive study involving the NGS of clinical trial samples allows for an elaborate genomic evaluation of trial participants, revealing both common and rare genetic variations. PGx includes the study of polymorphic differences in the determination of genomic-level drug/xenobiotic effects, drug response and disease susceptibility, and genotype/phenotype relationships. Therefore, the greater adoption of genotyping in various research areas would eventually lead to a rise in the demand for these techniques, creating significant opportunities in the market in the coming years.

Genotyping Market Report Segmentation Analysis

Key segments that contributed to the derivation of the genotyping market analysis are product type, technology, application, and end user.

• Based on product type, the genotyping market is divided into instruments, reagents and kits, bioinformatics, and genotyping services. The reagents and kits segment held the largest market share in 2023.
• Based on technology, the genotyping market is divided into microarrays, capillary electrophoresis, sequencing, matrix-assisted laser desorption/ionization-time of flight (MALDI-ToF) mass spectrometry, polymerase chain reaction (PCR), and others. The PCR segment held the largest market share in 2023.
• By application, the genotyping market is segmented into pharmacogenomics, diagnostics and personalized medicine, animal genetics, agricultural biotechnology, and others. The diagnostics and personalized medicine segment held the largest share of the market in 2023.
• Based on end user, the genotyping market is divided into pharmaceutical and biopharmaceutical companies, diagnostic and research laboratories, academic institutes, and others. The pharmaceutical and biopharmaceutical companies segment held the largest market share in 2023.

Genotyping Market Share Analysis by Geography

The geographic scope of the genotyping market report is mainly divided into five regions: North America, Asia Pacific, Europe, and the Middle East & Africa. North America dominated the market in 2023. Increasing adoption of technologically advanced products and solutions, and surging research and development activities are the factors benefiting the genotyping market in this region. Moreover, government-led programs such as the "All of Us Research Program," initiatives by various genomic communities, and the increasing awareness of genotyping services propel the market expansion across North America. Asia Pacific is anticipated to register the highest CAGR during the forecast period.

Genotyping Market Report Scope

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Genotyping Market News and Recent Developments

The genotyping market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. A few of the developments in the market are listed below:

• Standard BioTools Inc. launched NGS library preparation functionality on the X9 High-Throughput Genomics System. With this launch, customers can now perform real-time PCR and next-generation sequencing (NGS) library prep applications on a single benchtop system for the first time to support discovery through screening. (Source: Standard BioTools Inc., Company Website, May 2023)
• Bio-Rad Laboratories, Inc. launched PTC Tempo 48/48 and PTC Tempo 384 Thermal Cyclers, designed to support PCR applications in basic and translational research, process development, and quality control. The PTC Tempo 48/48 and PTC Tempo 384 Thermal Cyclers are the latest additions to the Bio-Rad portfolio of conventional PCR thermal cyclers. (Source: Bio-Rad Laboratories, Inc., Company Website, September 2022)

Genotyping Market Report Coverage and Deliverables

The "Genotyping Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:

• Genotyping market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
• Genotyping market trends as well as market dynamics such as drivers, restraints, and key opportunities
• Detailed PEST/Porter's Five Forces and SWOT analysis
• Genotyping market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
• Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the genotyping market
• Detailed company profiles