MENA Knee Cartilage Repair Service Market to Grow at a CAGR of 5.5% to reach US$ 344.50 million from 2022 to 2030

The MENA knee cartilage repair service market size is expected to grow from US$ 222.56 million in 2022 and to reach a value of US$ 344.50 million by 2030; it is anticipated to record a CAGR of 5.5% from 2022 to 2030.

Market Insights and Analyst View:

Knee cartilage repair is a type of treatment for knee preservation. The knee cartilage damage usually occurs in younger people (less than 50 years), after an injury, such as twisting your knee, smashing your kneecap, or fracturing your knee. Cartilage may wear down over time as part of natural aging for the people over 50. Knee cartilage repair depends on factors including the depth, size, and location of the torn knee cartilage, associated knee injuries, patient’s activity level and patient’s weight and age. Although some of the cartilage injuries can be treated non-operatively, but in cases with a focal cartilage defect a surgical knee cartilage treatment is commonly needed. The most common knee cartilage repair procedures are microfracture and chondroplasty.

Tissue engineering, Cells, ACI, MSC, Scaffolds are some of the sources that are currently available for cartilage regeneration. Tissue engineering combines biomaterials, cells, and biological factors to revive the damaged tissues, overcoming usual therapeutic strategies. Scaffolds are well acknowledged in regenerative applications as they are able to provide the appropriate environment for cells, reduce surgical morbidity, can be easily implanted, allow enhanced cell proliferation, an efficient, maturation and complete combination with surrounding articular cartilage.

Additive Manufacturing three-dimensional (3D) printing is an emerging technologies that will allow further improvement of the treatment. 3D printing replicates the damaged tissue shape starting from a patient medical image. It creates scaffolds through the progressive addition of material layer by layer until reaching the desired shape. The technology can mimic cartilage organization, extracellular matrix (ECM) composition, and functional and mechanical properties. There is also the demand to develop minimally invasive and cost-effective strategies which do not require long-lasting hospitalization.

Growth Drivers and Challenges:

Various studies have shown that arthritis is commonly identified as a public health concern in adults. In addition, the inflammation of the joints is increasing in the younger population and is contributing to the rise of osteoarthritis. According to the research article ”Assessing the Burden of Osteoarthritis in Africa and the Middle East: A Rapid Evidence Assessment,” published in February 2023 by Dovepress, in MENA, the age-standardized prevalence of OA in 2019 was 5,342.8 per 100,000 people. Similarly, the annual incidence rate of OA in 2019 was 430.4 per 100,000 people. The prevalence is expected to increase as the population ages. Other factors that give rise to the incidence are obesity and menopause in females. According to ”Prevalence of Symptomatic Knee Osteoarthritis in Saudi Arabia and Associated Modifiable and Non-Modifiable Risk Factors: A Population-Based Cross-Sectional Study,” published in March 2023 by the National Library of Medicine, 60.6% of people of age group 66–75 and 30.8% of people of age group 46–55 were affected by OA in Saudi Arabia. The report also stated that 39.75% of the total population in Saudi Arabia, including 60.9% of females and 53.3% of males, suffers from knee OA. Therefore, the rise in the prevalence of osteoarthritis is increasing the demand for cartilage repair procedures across the region.

In many Low- and Middle-Income Countries (LMICs) the surgical care is extremely limited. According to a study by the WHO there is a shortage of health workers in Africa. The shortage is more acute at the crucial levels of primary healthcare delivery, including nurses, community health workers and public health officers. A survey of 47 African countries, finds that the region has a ratio of 2:1000, which means for 1000 people only 2 health workers (physicians, nurses and midwives) are available. This is below the WHO threshold density which states that there should be 5 health workers per 1000 people should be there to deliver essential health services. Also, the health workforce is unevenly distributed in the region. The shortage of health worker in Africa is due to various factors such as fast population growth, weak governance of the health workforce, inadequate training capacity, international migration, and poor retention of health personnel. According to WHO, ~80% of Africa is experiencing medical staff shortages and high rates of healthcare professionals leaving to work in other countries. It is estimated that the health workers shortage in Africa, by 2030 will reach 6.1 million a 45% increase from 2013.

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MENA Knee Cartilage Repair Service Market: Strategic Insights

Market Size Value in	US$ 222.56 million in 2022
Market Size Value by	US$ 344.50 million by 2030
Growth rate	CAGR of 5.5% from 2022 to 2030
Forecast Period	2022-2030
Base Year	2022

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Report Segmentation and Scope:

The MENA knee cartilage repair service market is segmented on the basis of procedure type, and end user. By procedure type, the market is segmented into arthroscopic chondroplasty, microfracture, cell-based cartilage repair, osteochondral grafts transplantation, and others. The MENA knee cartilage repair service market, by end user, is segmented into hospitals, ambulatory surgical centers, and orthopedic clinics. The MENA knee cartilage repair service, based on geography, is segmented into Saudi Arabia, UAE, Egypt, Israel, and Rest of Middle East & Africa.

Segmental Analysis:

By procedure type, the knee cartilage repair service market is segmented arthroscopic chondroplasty, microfracture, cell-based cartilage repair, osteochondral grafts transplantation, and others. In 2022, the arthroscopic chondroplasty segment held the largest share of the market. However, the market for cell-based cartilage repair segment is expected to grow at the fastest CAGR during 2022–2030. Arthroscopic chondroplasty is a common surgical procedure performed using an arthroscope (a small, fiber-optic instrument comprising a lens, light source, and video camera) during knee arthroscopy. During the process, the doctor creates two to five small incisions around the knee. Through one of the cuts an arthroscopic camera is inserted, and other incisions act as access points for other arthroscopic tools.

MENA Knee Cartilage Repair Service Market, by Procedure Type – 2022 and 2030

Based on end user, the knee cartilage repair service market is divided into hospitals, ambulatory surgical centers, and orthopedic clinics. The hospitals segment held the largest share of the market in 2022. The same segment is anticipated to register the highest CAGR in the market during 2022–2030. The hospitals segment is the largest end user segment in the knee cartilage repair service market. The segment's growth is attributed to the increased number of procedures for knee injuries and other orthopedic treatments. Hospitals provide treatment with specialized nursing staff and medical equipment. They house various orthopedic surgical procedures, including critical surgeries, such as arthroplasty, and fusion techniques, such as artificial knee joints and other procedures that demand high precision and accuracy.

Regional Analysis:

Based on geography, the MENA knee cartilage repair service market is divided into Saudi Arabia, UAE, Egypt, Israel, and Rest of Middle East & Africa. Saudi Arabia is one of the fastest-growing countries in the MENA, driven by a huge population base and an increase in the prevalence of chronic diseases. Saudi Arabia has seen a significant change in lifestyle due to the rapid economic transition and associated technological and social changes. A high sedentary behavior and a change in dietary patterns, with people favoring energy-dense foods such as fast foods and sugar-sweetened beverages over nutrient-dense foods was observed. As per an Al Arabiya Network article and the latest figures revealed ahead of World Obesity Day (March 4) in 2023, ~60% of the country's adult population is overweight or obese, and anterior cruciate ligament (ACL) injury is among the most common orthopedic injuries. A high body mass index (BMI) contribute to the development of noncontact ACL injury, and the risk of ACL tears was significantly higher across obese patients.

Knee Cartilage Repair Service Market Opportunity:

Artificial Intelligence (AI) to Diagnose Cartilage Defects

The growing technological advancements have enabled the use of AI to diagnose cartilage defects. Using AI, it is possible to identify the precise segmentation and robust assessment of chondral lesions, including diameter, shape, location, shape, and boundaries. Market players have developed AI tools and solutions for effective and efficient imaging technologies for all orthopedic segments. For instance, an Israel-based company, RSIP Vision, has developed an AI tool that accurately assesses chondral lesions in magnetic resonance imaging (MRI) scans for hips, knees, and ankles using noninvasive techniques. The AI tool offers an accurate measurement of osteochondral lesions that helps physicians evaluate the damage's severity and select an effective treatment plan. The tool also helps in assessing the efficacy of the treatment. Such innovations are expected to drive the knee cartilage repair service market as the prevalence of chondral lesions is much higher in older and young people. Moreover, articular cartilage has avascular nature, which limits its healing potential. In many cases, chondral lesions restrict athletes from participating in sports and may affect their daily activities. Therefore, the use of AI in diagnosing cartilage defects is expected to assist in choosing better treatment plans and eventually contribute to the growth of the market in the near future.  

Competitive Landscape and Key Companies:

A few of the prominent players operating in the MENA knee cartilage repair service market are Arthrex Inc, DePuy Synthes Inc, Zimmer Biomet Holdings Inc, Medacta Group SA, Anika Therapeutics Inc, Conmed Corp, Stryker Corp, CartiHeal Inc, Smith & Nephew Plc, and B. Braun SE. These companies focus on the development of new technologies, advancements in existing products, and expansion of geographic footprint to meet the growing consumer demand worldwide and expand their product range in specialty portfolios. Companies in the MENA knee cartilage repair service market are implementing various inorganic and organic developments. A few of the instances are mentioned below:

• In March 2022, US Food and Drug Administration had granted Premarket Approval (PMA) for its Agili-C implant of CartiHeal Ltd. CartiHeal Ltd is a developer of implants for the treatment of cartilage and osteochondral defects in arthritic and non-arthritic knee joints.
• In December 2021, DePuy Synthes Acquired OrthoSpin, Ltd. OrthoSpin developed and manufactures a first-of-its kind technology – an automated strut system – which is used in conjunction with DePuy Synthes MAXFRAME Multi-Axial Correction System, an external ring fixation system. This acquisition is a clear example of Johnson & Johnson’s continued commitment to advancing innovation in the medtech space