The protein expression market is expected to reach US$ 4,000.67 million in 2028 from US$ 2,221.73 million in 2021. The market is estimated to grow with a CAGR of 8.8% from 2021-2028.
The scope of the Protein Expression market includes product type, services, application, end user, and region. Based on region, the Protein Expression market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the Protein Expression market emphasizing on various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players across the world. It also includes COVID–19 impact analysis across the regions.
Market Insights
Increasing Applications of Protein Expression
Protein expression, an integral tool in biological research, is increasingly vital as a pharmaceutical production mechanism for biological therapeutics. The combination of old technologies, such as artificial enzymes, and new next-generation expression systems is revitalizing protein expression protocols. The development of genetic engineering and cloning has opened many possibilities for the expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled the expression and isolation of recombinant proteins on a large scale.
The demand for recombinant proteins for human application is increasing day by day. There is a huge demand for novel and improved bioprocessing strategies that are cost-effective and time-saving. The continuous improvement in biopharmaceutical expression systems has led to the production of quality products. Modern molecular biology techniques are at the forefront of the production of biopharmaceutical proteins using various prokaryote or eukaryote expression systems. Different innovative techniques, such as systems biology, metabolic engineering, and CRISPR/Cas systems, can be applied for strain engineering to improve bioprocess performance and generate biologically active and stable proteins.
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The global burden of dengue is rapidly increasing and will continue until the development of an effective vaccine against it. Various vaccine candidates for dengue are at preclinical and clinical trials stages of development based on different approaches. A few vaccines are a tetravalent, live attenuated virus, purified inactivated virus, recombinant proteins subunit, plasmid DNA, and virus-vectored dengue vaccines. Recent progress on recombinant subunit-based dengue vaccine candidates using various approaches, such as fusion with other immunogenic epitopes, use of a novel adjuvant, protein expression in different host systems, designer vaccine, and VLPs development, is opening new avenues for the development of a fully efficacious vaccine against dengue.
Currently, more than 65 million confirmed cases and over 1.5 million deaths are reported. The COVID-19 pandemic has led to significant health, social, and global economic crises. The development of a vaccine for COVID-19 is an effective strategy to control the outbreak. It is required that the vaccine is produced at high speed and is easily scalable. Recombinant protein, viral-vectored or nucleic acid-based (recombinant plasmid DNA and mRNA) vaccines need to be considered to shorten the vaccine production timeframe. The use of protein expression is increasing during vaccine development due to the advantages of recombinant protein, which drives the growth of the protein expression market.
Product Type-Based Insights
Based on product type, the protein expression market is segmented into instruments, reagents, expression vectors, and competent cells. The reagents segment held the largest share of the market in 2021. Also, the reagents segment is estimated to register the highest CAGR of 9.5% in the market during the forecast period.
Services-Based Insights
Based on services, the protein expression market is segmented into antibody development & production, protein expression & production, hybridoma one-stop services, stable cell line development, bioanalytical assay services. The antibody development & production segment held the largest share of the market in 2021. However, same segment is estimated to register the highest CAGR of 9.7% in the market during the forecast period.
Application-Based Insights
Based on application, the protein expression market is segmented into research, therapeutic, industrial. The therapeutic segment held the largest share of the market in 2021 and same segment is estimated to register the highest CAGR of 9.4% in the market during the forecast period.End User-Based Insights
Based on end user, the protein expression market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations. The pharmaceutical and biotechnology companies segment held the largest share of the market in 2021. Also, the segment is estimated to register the highest CAGR of 5.6% in the market during the forecast period.
Inorganic strategies such as partnerships, and mergers and acquisitions are commonly adopted by companies to cater to changing customer demand and maintain their brand name across the world. Market players operating in the Protein Expression market also adopt organic strategies such as product launch and expansion to outstretch their footprint and product portfolio worldwide as well as to meet the growing demand.
Protein Expression Market Regional Insights
The regional trends and factors influencing the Protein Expression Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Protein Expression Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.
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Protein Expression Market Market Report Scope
Report Attribute | Details |
---|---|
Market size in 2021 | US$ 2.22 Billion |
Market Size by 2028 | US$ 4 Billion |
Global CAGR (2021 - 2028) | 8.8% |
Historical Data | 2019-2020 |
Forecast period | 2022-2028 |
Segments Covered |
By Product
|
Regions and Countries Covered | North America
|
Market leaders and key company profiles |
Market Players Density: Understanding Its Impact on Business Dynamics
The Protein Expression Market market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.
Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.
Major Companies operating in the Protein Expression Market are:
- Thermo Fisher Scientific, Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
Disclaimer: The companies listed above are not ranked in any particular order.
- Get the Protein Expression Market top key players overview
By Product Type
- Competent Cells
- Expression Vectors
- Reagents
- Instruments
By Services
- Antibody Development & Production
- Protein Expression & Production
- Hybridoma One-Stop Services
- Stable Cell Line Development
- Bioanalytical Assay Services
By Application
- Research
- Therapeutic
- Industrial
By End User
- Pharmaceutical and Biotechnology Companies
- Contract Research Organizations
- Academic Research Institutes
- Others
By Geography
- North America
- US
- Canada
- Mexico
- Europe
- France
- Germany
- Italy
- UK
- Spain
- Rest of Europe
- Asia Pacific (APAC)
- China
- India
- South Korea
- Japan
- Australia
- Rest of APAC
- Middle East & Africa (MEA)
- South Africa
- Saudi Arabia
- UAE
- Rest of MEA
- South and Central America (SCAM)
- Brazil
- Argentina
- Rest of SCAM
Company Profiles
- Thermo Fisher Scientific, Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories, Inc.
- QIAGEN
- New England Biolabs.
- Promega Corporation
- Oxford Expression Technologies Ltd
- Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
- PEST and SWOT Analysis
- Market Size Value / Volume - Global, Regional, Country
- Industry and Competitive Landscape
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Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Protein Expression Market Forecast to 2028 - Covid-19 Impact and Global Analysis - By Product ; Services ; Application ; End User and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
North America held highest market share in 2021.
Asia Pacific is projected to be the fastest growing region in the global market.
The costs of the Protein Expression are much higher, and they may cost US$ 300–1500, or more, per type. The cost may also differ from product to product types.
The Protein Expression market is anticipated to grow around 8.8% CAGR amid the forecast period 2021-2028.
Driving factors such as an development in the arena of proteomics and biotechnology industry, rising incidences of chronic and autoimmune diseases, rise in the awareness among people regarding protein expression, increasing focus on research and development process, growing usage of protein expression technologies in industrial protein manufacturing organizations, and rise in adoption of protein-based drugs over non-protein-based drugs are the prime growth drivers of protein expression market. In addition, increase in adoption of protein expression in emerging economies such as China, India and others, will create new opportunities for protein expression market. However, higher cost of the research and development, and complex government approval processes are the key restraints for protein expression market.
Protein expression is a process in which proteins are synthesized, modified and regulated. Protein expression involves laboratory techniques & procedures which aid in manufacture of proteins. The technique allows to produce and purify the desired protein, either inside or outside a cell. The proteins synthesized using protein expression technique can be used for industrial processes or to diagnose and to treat diseases. Protein expression provides substrates or enzymes required for further analysis
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The List of Companies - Protein Expression Market
- Thermo Fisher Scientific, Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories, Inc.
- QIAGEN
- New England Biolabs.
- Promega Corporation
- Oxford Expression Technologies Ltd