Constipation Treatment Market Size and Growth 2031

Constipation Treatment Market Size and Forecast (2021–2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Therapeutic (Laxatives, Chloride Channel Activators, Peripherally Acting Mu-Opioid Receptor Antagonists, GC-C Agonists, and 5-HT4 Receptor Agonists), Disease (Chronic Idiopathic Constipation, Irritable Bowel Syndrome with Constipation, and Opioid-Induced Constipation), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and Geography

  • Report Code : TIPRE00005408
  • Category : Pharmaceuticals
  • No. of Pages : 150
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Constipation Treatment Market Growth Analysis Report, 2031

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The Constipation Treatment Market size is projected to reach US$ 17.69 billion by 2031 from US$ 9.93 billion in 2022. The market is expected to register a CAGR of 6.0% in 2023–2031. The increasing demand for the treatment of Opioid-Induced constipation are likely to remain key Constipation Treatment Market trends.

Constipation Treatment Market Analysis

Increasing prevalence of constipation among large population is one of the major factors driving the growth of constipation treatment market. It is one of the common conditions experienced by 16% of the global population with the prevalence of 33.5% in 2023. There are various factors associated with the increasing prevalence of constipation among adults include improper diet, lack of physical activity, reduced bowel movement due to age progression among others. Constipation can cause psychological morbidity which affects the quality of life. thus, surging prevalence of constipation is expected to anticipate the growth of constipation treatment market.

Constipation Treatment Market Overview

Constipation treatment market is mainly driven by the increasing prevalence of constipation caused due to various factors such as lifestyle, medication, and medical conditions followed by the increasing product development, launches and approval for the treatment of constipation. Additionally, surge in geriatric population prone to constipation along with changing dietary habits followed by the increasing prevalence of gastrointestinal disorders are expected to contribute the growth of constipation treatment market. Furthermore, increase in awareness campaign by various organization and manufacturers along with surge in research and development activities for the development of innovative treatment option for constipation anticipated the market growth.

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Constipation Treatment Market: Strategic Insights

constipation-treatment-market
Market Size Value inUS$ 8,533.89 Million in 2019
Market Size Value byUS$ 13,386.19 Million by 2027
Growth rateCAGR of 5.9% from 2020-2027
Forecast Period2020-2027
Base Year2020
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Constipation Treatment Market Drivers and Opportunities

Increasing Product Launches and Approvals to Favor Market

Increasing number of FDA approvals and drug development activities are likely to accelerate the market's growth during the forecast period. The majority of the established and new players are coming forward to manufacture drugs for constipation, which would lead to high availability of drugs in the market. This, in turn, is expected to boost the consumption of these drugs, thereby fuelling the growth of the constipation treatment market. For instance, in 2021, The US Food and Drug Administration (FDA) has approved the first generic drug linaclotide 145 mcg capsules, as well as 290 mcg capsules from Mylan Pharmaceuticals to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation. Thus, the increasing number of product launches and approvals are expected anticipate the constipation treatment market growth during the forecast period.

Drug Developments for Constipation– An Opportunity for the Market Growth

Laxatives are highly recommended as a conventional treatment for acute and mild constipation. Developments in the pharmaceutical industry have received approvals for drugs, such as lubiprostone, linaclotide, and prucalopride. However, there are essential unmet needs to treat constipation among patients who do not respond to current therapies. The recent developments and product launch for 5-HT4 receptor modulators velusetrag, naronapride, the guanylate cyclase C agonist plecanatide, and the ileal bile acid transporter inhibitor elobixibat have been recognized as promising drugs. However, various studies are being conducted to analyze effectiveness of drugs that can offer substantial relief from constipation. For instance, in April 2022, Ardelyx, Inc. launched IBSRELA, the first and only NHE3 inhibitor for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults. Additionally, in August 2022, FDA has approved the use of Vibrant a first-of-its-kind therapy manufactured by Vibrant Gastro for the treatment of chronic constipation. Therefore, the launch of such innovative products is expected to provide lucrative growth opportunities.

Constipation Treatment Market Report Segmentation Analysis

Key segments that contributed to the derivation of the Constipation Treatment Market analysis are therapeutic, disease, distribution channel.

  • Based on therapeutic, the Constipation Treatment Market is segmented into laxatives, chloride channel activators, peripherally acting MU-opioid receptor antagonists, GC-C agonists, and 5-HT4 receptor agonists. The laxatives segment held a larger market share in 2023.
  • By disease, the market is segmented into chronic idiopathic constipation, irritable bowel syndrome with constipation, and opioid-induced constipation. The chronic idiopathic constipation segment held the largest share of the market in 2023.
  • In terms of distribution channel, the market is classified into Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies. The retail pharmacies segment dominated the market in 2023.

Constipation Treatment Market Share Analysis by Geography

The geographic scope of the Constipation Treatment Market report is mainly divided into five regions: North America, Asia Pacific, Europe, Middle East & Africa, and South & Central America.

North America has dominated the Constipation Treatment Market owing to the increasing prevalence of constipation among all groups. The significantly increasing geriatric population in North American countries is expected to contribute widely to its growth. Similarly, market players involved in developing drugs treating constipation are likely to foster market growth during the forecast period. Whereas, in Mexico, the pharmaceutical industry's developments and market players' involvement to enhance awareness regarding constipation and its treatment are expected to serve vital growth opportunities for the market's growth. Asia Pacific is anticipated to grow with the highest CAGR in the coming years.

Constipation Treatment Market Report Scope

Constipation Treatment Market News and Recent Developments

The Constipation Treatment Market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. The following is a list of developments in the market for constipation and strategies:

  • Lupin Life, the consumer healthcare business of global pharma major, Lupin Limited launched the Softovac Liquifibre, a 100% Ayurvedic liquid laxative. With this, the company enters the Indian liquid laxative market with this innovative product that is a formulation of Isabgol fibre in liquid form and natural actives such as Sonamukhi, Harad, Mulethi, Saunf, Amaltas and Gulab Dal. (Source: Lupin, Company Website, 2023)
  • Ironwood Pharmaceuticals, Inc. a GI-focused healthcare company, received U.S. Food and Drug Administration (FDA) approval for LINZESS (linaclotide) as a once-daily treatment for pediatric patients ages 6-17 years-old with functional constipation. LINZESS is the first and only FDA-approved prescription therapy for functional constipation in this patient population. (Source: Ironwood, Company Website, 2023)
  • EA Pharma’s parent company Eisai Co., Ltd. and Mochida Pharmaceutical Co., Ltd. launched MOVICOL HD for the treatment of chronic constipation in Japan. MOVICOL HD contains the same active ingredients in double the quantity of MOVICOL LD per sachet. It increases the water retention in the intestinal tract by osmolality of its main ingredient polyethylene glycol (macrogol 4000), which increases fecal moisture, softens feces, increases fecal volume and physiologically activates the peristaltic movement of the colon to promote bowel movement. (Source: Eisai Co., Ltd., Company Website, 2022)
  • Ardelyx, Inc. launched IBSRELA, the first and only NHE3 inhibitor for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults. It treats the abdominal pain, bloating, and discomfort, along with the constipation associated with this debilitating condition. (Source: Ardelyx, Inc., Newsletter, 2022)

Constipation Treatment Market Report Coverage and Deliverables

The “Constipation Treatment Market Size and Forecast (2021–2031)” report provides a detailed analysis of the market covering below areas:

  • Market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
  • Market dynamics such as drivers, restraints, and key opportunities
  • Key future trends
  • Detailed PEST/Porter’s Five Forces and SWOT analysis
  • Global and regional market analysis covering key market trends, major players, regulations, and recent market developments
  • Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments
  • Detailed company profiles
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Therapeutic ; Disease ; Distribution Channel , and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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