[Research Report] The dental bone graft substitute market size was US$ 533.5 million in 2022 and is projected to reach US$ 1,011.2 million by 2030. It is expected to register a CAGR of 8.3% in 2022-2030.

Market Insights and Analyst View:

The dental bone graft substitute market size is growing rapidly due to the increasing number of dental diseases and growing instances of dental procedures due to cosmetic appearance. The increasing prevalence of dental diseases and the introduction of supportive government initiatives regarding dental bone graft substitutes are among the most enduring growth drivers of the dental bone graft substitute market. These bone graft substitutes are also used in cosmetic dental procedures, owing to which there is notable demand for cosmetic procedures, especially in high-income countries.

Growth Drivers and Challenges:

The increasing burden of periodontal diseases and oral cancer, and the growing demand for dental cosmetic procedures drives the dental bone graft substitute market growth. Oral diseases are highly preventable. However, these diseases are major health issues in many countries and affect people throughout their lifetime. Several common dental issues include periodontal diseases, dental caries (tooth decay), and tooth loss. The increasing prevalence of dental diseases is causing the need for teeth replacement, dental crowns, copings, and dental bridges. As per the World Health Organization (WHO) Global Oral Health Status Report (2022), about 3 out of 4 people are affected due to oral diseases globally, of which ~3.5 billion people live in middle-income countries. Additionally, ~2 billion people globally suffer from dental caries in permanent teeth, and about 514 million children suffer from primary teeth caries. The growing prevalence rate of dental problems such as crooked teeth, overbites, spaces between teeth, and teeth overcrowding is creating the demand for dental bone graft substitute to treat such problems. For instance, as per the Centers for Disease Control and Prevention (CDC), in the US, about 47.2% of the adults above 30 years of age have some periodontal disease, which increases with age; and about 70.1% of adults over the age of 65 years suffered from periodontal disease in 2020. This surging number of people suffering from dental diseases is fueling the demand for dental bone graft substitute for easy and rapid treatment. Therefore, the increase in prevalence of oral diseases worldwide is fueling the growth of the market.

Digitization of dentistry with CAD/CAM technology is expected to bring new dental bone graft substitute market trends in the coming years.

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Dental Bone Graft Substitute Market: Strategic Insights

Market Size Value in	US$ 533.5 million in 2022
Market Size Value by	US$ 1,011.2 million by 2030
Growth rate	CAGR of 8.3% from 2022 to 2030
Forecast Period	2022-2030
Base Year	2022

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Report Segmentation and Scope:

The dental bone graft substitute market analysis has been carried out by considering the following segment type, application, end user, and geography. The market, by type, is segmented into autograft, allograft, xenograft, synthetic bone graft, and others. Based on application, the market is segmented into socket preservation, ridge augmentation, periodontal dental regeneration, implant bone regeneration, and sinus lift. The market, by end user, is segmented into hospital, dental clinics, and others. Geographically, the scope of the dental bone graft substitute market report is primarily divided into North America (the US, Canada, and Mexico), Europe (Spain, the UK, Germany, France, Italy, and the Rest of Europe), Asia Pacific (South Korea, China, Japan, India, Australia, and the Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, the UAE, and the Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America).

Segmental Analysis:

The dental bone graft substitute market, based on type, is segmented into autograft, allograft, xenograft, synthetic bone graft, and others. In 2022, the autograft segment held the largest dental bone graft substitute market share. The xenograft segment is expected to record the highest CAGR of the dental bone graft substitute market during 2022–2030. Autografts are commonly obtained from extraoral and intraoral sites, such as the mandibular ramus, mandibular symphysis, external oblique ridge, proximal ulna, iliac crest, or distal radius, of the individual undergoing treatment, as they are good sources of cortical and cancellous bone. Autografts are associated with higher surgical costs and involve significant surgical risks, e.g., inflammation, excessive bleeding, pain and infection, limiting their application to smaller bone defects. Although other bone substitutes are routinely used to treat localized alveolar bone defects and maxillary bone grafts in dental applications, block-form autografts are still routinely used in alveolar ridge augmentation procedures. Autografts are the preferred material for complex augmentation procedures, such as posterior mandibular edentulous reconstruction, because only a few bone substitute materials can produce a volume of newly formed bone comparable to autograft materials. Xenografts are transplant materials derived from a genetically unrelated species of the host. Natural bone substitutes promote enhanced osteogenic, osteoconductive, and osteoinductive potentials by creating a favorable microenvironment for bone growth. Most xenografts derived from cattle are sterilized and processed for safe implantation into human tissue. These xenografts can be freeze-dried or demineralized and deproteinized. Xenografts are usually distributed only as a calcified matrix. Madrepore and Millepore corals are harvested and processed to become coral-derived granules (CDG) and other coral xenografts. Despite the promising prospects for many xenograft materials, a few limitations are still associated with the use of xenograft bone substitutes. These include the variable rates of resorption, lack of viable cells and biological components, and need for tissue treatment processes that allow retention of osteoinductive cells.

The dental bone graft substitute market, by application, is segmented into socket preservation, ridge augmentation, periodontal dental regeneration, implant bone regeneration, and sinus lift. In 2022, the socket preservation segment held the largest market share and is anticipated to record the highest CAGR during 2022–2030.

The market, by end user, is segmented into hospital, dental clinics, and others. In 2022, the dental clinics segment held the largest dental bone graft substitute market share and is expected to record the highest CAGR during 2022–2030.

Regional Analysis:

Geographically, the market is divided into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. North America is the biggest contributor to the global dental bone graft substitute market growth. Asia Pacific is predicted to show the highest CAGR in the market during 2022–2030. Significant changes have occurred in dental practice over the past 20 years in the US.  As per the CDC report, 1 in 4 (26%) adults in the US have untreated tooth decay. Additionally, nearly half (~46%) of all adults aged 30 years or older show signs of gum disease, severe gum disease affecting about 9% of adults. Furthermore, technological advancements in dentistry provide numerous advantages for facilitating the work of dentists and users of dental services that are becoming more demanding in terms of aesthetics.

Dental Bone Graft Substitute Market Report Scope

Industry Developments and Future Opportunities:

The dental bone graft substitute market forecast is estimated on the basis of various secondary and primary research findings such as key company publications, association data, and databases. Strategies by key players operating in the market are listed below:

• In April 2023, ZimVie Inc. announced the launch of two products, RegenerOss CC Allograft Particulate and RegenerOss Bone Graft Plug. The launch of these products has extended ZimVie, Inc.'s biomaterials portfolio intended for filling extraction sockets and periodontal defects. The products are commercially available in North America.

Competitive Landscape and Key Companies:

Dentsply Sirona Inc, Dentium Co Ltd, Geistlich Pharma AG, ZimVie Inc, Keystone Dental Inc, Straumann Holding AG, Medtronic Plc, BioHorizons Inc, MEDOSIS, and LifeNet Health Inc are among the prominent players profiled in the dental bone graft substitute market report. In addition, several other players have been studied and analyzed during the study to get a holistic view of the market and its ecosystem. These companies focus on geographic expansions and new product launches to meet the growing demand from consumers worldwide and increase their product range in specialty portfolios. Their global presence allows them to serve a large customer base, subsequently facilitating market expansion.