Endothelial Dysfunction Market Growth Report and Size by 2031
The endothelial dysfunction market size is projected to reach US$ 2.94 billion by 2031 from US$ 2.08 billion in 2023. The market is expected to register a CAGR of 4.4% during 2023–2031. Noninvasive methods to assess endothelial dysfunction will likely remain a key trend in the market.
Endothelial Dysfunction Market Analysis
Globally, heart diseases are becoming more prevalent, with developed nations seeing a sharp rise in their incidence. Changes in lifestyle and other health issues are contributing to an increase in the incidences. There is a type of cardiovascular disease among adults in the US. By 2035, it is anticipated that more than 45.1% of Americans will suffer from a cardiovascular illness. This is expected to support the market's expansion throughout the projected period. Players like ZOLL Medical Corp, Sphingo Tec GmbH, Endothelix Inc, SMART Medical Ltd, Perimed AB, Everist Health Inc, Alam Medical SaRI, and Medizinische Messtechnik GmbH are among the key companies in the endothelial dysfunction market. Companies have been implementing strategies that have aided their growth and changed the market differently. The businesses have used both inorganic (like product launches, partnerships, and collaborations) and organic (like launches, expansion, and product approvals) strategies.
Endothelial Dysfunction Market Overview
A change in lifestyle raises the risk of endothelial dysfunction by increasing the incidence of diabetes, hypertension, dyslipidemia, and obesity. Proactive monitoring, early diagnosis, and physical activity can help prevent these. A collection of illnesses known as metabolic syndrome raises the risk of CAD, diabetes, high blood pressure, and other dangerous health issues. The National Heart, Lung, and Blood Institute (NHLBI) published an article on "Metabolic syndrome" that claims that metabolic diseases are common in the United States. That is, the metabolic syndrome affects one in three adult individuals. Already a severe public health issue, type 2 diabetes is becoming more common in children and young adults who are obese. The World Health Organization (WHO) reports that diabetes was a direct cause of 1.5 million deaths in 2019; of these deaths, 48% happened before the age of 70. Diabetes contributed to an additional 460,000 kidney disease-related deaths. Twenty percent of cardiovascular deaths are related to elevated blood sugar. Diabetes ranked as the eighth most common cause of death in the US in 2020, according to the CDC. Compared to adults without diabetes, adults 50 years of age and older with diabetes die 4.6 years earlier, become disabled 6-7 years earlier, and remain disabled for almost 1-2 years longer.
Furthermore, 4.4 million deaths worldwide are attributed to high cholesterol, according to the World Heart Federation. In high- and low-income nations alike, it poses a severe risk for heart disease and stroke. The World Health Organization estimates that 2.6 million deaths in 2022 were related to high cholesterol. As a risk factor for heart disease, high cholesterol is one of the leading causes of disease burden in both developed and developing nations. The rise in diseases like diabetes, obesity, high blood pressure, and cholesterol is primarily attributed to changing modes of transportation, physical immobility from inactivity at work, increased consumption of high-fat and high-sugar foods, and growing urbanization.
Consequently, the endothelial dysfunction market is expanding due to the increasing prevalence of these illnesses. It presents a significant risk for heart disease and stroke in both high- and low-income countries. According to estimates from the World Health Organization, high cholesterol will be a factor in 2.6 million deaths in 2022. High cholesterol is a significant contributor to the burden of disease in both developed and developing countries because it is a risk factor for heart disease. Increased consumption of high-fat and high-sugar foods, growing urbanization, and physical immobility from inactivity at work are all significant contributors to the rise in diseases like diabetes, obesity, high blood pressure, and cholesterol. The market for endothelial dysfunction is growing because of the rising incidence of these diseases.
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Endothelial Dysfunction Market: Strategic Insights
Market Size Value in US$ 1,995.17 million in 2022 Market Size Value by US$ 2,584.84 million by 2028 Growth rate CAGR of 4.4% from 2022 to 2028 Forecast Period 2022-2028 Base Year 2022
Mrinal
Have a question?
Mrinal will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Endothelial Dysfunction Market: Strategic Insights
| Market Size Value in | US$ 1,995.17 million in 2022 |
| Market Size Value by | US$ 2,584.84 million by 2028 |
| Growth rate | CAGR of 4.4% from 2022 to 2028 |
| Forecast Period | 2022-2028 |
| Base Year | 2022 |
Mrinal
Have a question?
Mrinal will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Endothelial Dysfunction Market Drivers and Opportunities
Increasing Incidence of Cardiovascular Diseases Favors the Market Growth
The Middle East and North Africa's leading cause of death, according to the World Heart Federation, is cardiovascular disease, which claims the lives of 1.4 million people a year or more. Furthermore, over the previous 30 years, there has been a 48% increase in CVD deaths, which have been responsible for 40% and 10% of deaths in Oman and Somalia, respectively. The Middle East and North Africa had age-standardized CVD death rates in 2021 that varied from 134.2 to 600.2 per 100,000 individuals. Thus, the market is driven by the high prevalence of endothelial dysfunction-related cardiovascular diseases.
Rising Usage of Novel Biomarkers and Therapeutic Strategies is Likely to Create Opportunities in the Market
Examining endothelial function can improve risk stratification and early disease detection and assess vascular response to therapeutic interventions. There are studies to understand the pathophysiological mechanisms underlying endothelial dysfunction and atherosclerosis progression in a better way and identify new biomarkers and therapeutic strategies to prevent endothelial dysfunction and atherosclerosis to reduce the risk of developing coronary artery disease (CAD) and related complications. Using liquid biopsies and new molecular biology techniques has enabled the identification of a growing list of molecular and cellular markers of endothelial dysfunction that have provided insight into the molecular basis of atherosclerosis as well as potential biomarkers and therapeutic targets for the prevention and treatment of atherosclerosis and CAD.
Further, therapeutic interventions to increase nitric oxide (NO) bioavailability in the vasculature can improve long-term cardiovascular outcomes in healthy, high-risk patients with advanced atherosclerosis. Current therapeutic strategies focus on enhancing the synthesis or reducing the oxidative inactivation of NO in the human vasculature. Of the available therapeutics, angiotensin-converting enzyme inhibitors and statins have improved endothelial function and cardiovascular outcomes after long-term use. Endothelial dysfunction can also be enhanced through other therapeutic approaches, including targeting NO synthesis through modulation of endothelial nitric oxide synthase (eNOS) coupling, such as folate and tetrahydrobiopterin. Therefore, rising inclination toward using novel biomarkers and growing therapeutic strategies are expected to provide opportunities for the endothelial dysfunction market.
Endothelial Dysfunction Market Report Segmentation Analysis
Key segments that contributed to the derivation of the endothelial dysfunction market analysis are cause, test type, and end user.
- Based on the cause, the endothelial dysfunction market is divided into hypertension, diabetes, hypercholesterolemia, Bechet’s disease, obesity, and others. The hypertension segment held the most significant market share in 2023.
- By test type, the market is categorized into invasive and noninvasive tests (flow-mediated dilatory, peripheral arterial tonometry (PAT), circulating markers, venous occlusion plethysmography, and others. The invasive tests segment held the largest share of the market in 2023.
- By end user, the market is segmented into hospitals, specialty clinics, ambulatory surgery centers, and others. The hospitals segment held the largest share of the market in 2023.
Endothelial Dysfunction Market Share Analysis by Geography
The geographic scope of the endothelial dysfunction market report is mainly divided into five regions: North America, Asia Pacific, Europe, Middle East & Africa, and South & Central America.
The US, Canada, and Mexico are the three leading nations that were used to analyze North America's endothelial dysfunction market. Rising investments in cardiology informatics and an increase in the prevalence of cardiac diseases are the leading causes of market expansion in the region. Due to factors like the growing prevalence of CAD, an established healthcare system, and research and development efforts aimed at creating cutting-edge endothelial dysfunction medications and devices, the US has the largest endothelial dysfunction market in North America. In the United States, coronary heart disease is the primary cause of death. Since the US has the biggest economy in North America, its population trend significantly impacts any market's growth. The number of Americans 65 and older is predicted to more than double between 2016 and 2026 (from 46 million in 2016 to over 98 million by 2060), making up ~24% of the total population, up from 15%, according to data from the US Bureau of Labor Statistics. The American Heart Association estimates that approximately 6 million adults in the US suffer from heart failure, and that number is expected to rise by 40% by 2035. Approximately half of all adults in the US have some form of cardiovascular disease (CVD). By 2035, it is anticipated that over 130 million adults, or 45.1% of the US population, will suffer from CVD.
Endothelial Dysfunction Market Report Scope
Endothelial Dysfunction Market News and Recent Developments
The endothelial dysfunction market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. A few of the developments in the endothelial dysfunction market are listed below:
- Perimed has signed an agreement with Lovell Government Services. Lovell’s customers are Federal, State, and Local Governments such as the Department of Veteran Affairs (VA), Defense Logistics Agency, and Department of Defense in the United States. With this agreement, Perimed gains an additional sales channel as Lovell will notify the company of any government contract opportunities within its field of business and bid on Perimed’s behalf. (Source: Perimed AB, Press Release, April 2023)
Endothelial Dysfunction Market Report Coverage and Deliverables
The “Endothelial Dysfunction Market Size and Forecast (2021–2031)” report provides a detailed analysis of the market covering below areas:
- Endothelial dysfunction market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Endothelial dysfunction market trends as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST/Porter’s Five Forces and SWOT analysis
- Endothelial dysfunction market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments.
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the endothelial dysfunction market
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Cause, Test Type, and End User
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The market is expected to register a CAGR of 4.4% during 2023–2031.
ZOLL Medical Corp, Everist Health Inc, Sphingo Tec GmbH, Endothelix Inc, SMART Medical Ltd, Alam Medical SaRI, Perimed AB, Lawrence Berkeley National Laboratory, The Polymath Co, Medizinische Messtechnik GmbH, Boehringer Ingelheim International
Key factors driving the market are the increasing incidence of cardiovascular diseases and high cholesterol, diabetes, and obesity.
Noninvasive methods to assess endothelial dysfunction will likely remain a key trend in the market.
North America dominated the endothelial dysfunction market in 2023
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
Get Free Sample For