Gene Editing Market Size Report | Growth & Share Forecasts till 2030

Gene Editing Market Size and Forecasts (2020 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Component (Reagents and Consumables, Software and Systems, and Services), Technology (Clustered Regularly Interspaced Short Palindromic Repeats, Transcription Activator-Like Effector Nucleases, Zinc Finger Nucleases, and Other Technologies), Application (Genetic Engineering and Clinical Applications), End User (Pharmaceutical companies and Biotechnology Companies, Academics and Government Research Institutes, and Clinical Research Organizations), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)

  • Report Code : TIPRE00032626
  • Category : Biotechnology
  • No. of Pages : 150
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Gene Editing Market Size Report | Growth & Share Forecasts till 2030

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[Research Report] The gene editing market size is projected to grow from US$ 6,542.95 million in 2022 to US$ 23,902.34 million by 2030; it is estimated to record a CAGR of 17.6% during 2022–2030.

Market Insights and Analyst View:

Gene editing, also called genome editing, is a technique for modifying an organism's DNA using a variety of methods. Conditions such as cystic fibrosis, sickle cell disease, cancer, and others can be treated and prevented through gene editing. The growth of the gene editing market is anticipated to be fueled by rising government funding, an increase in the number of genomics projects, and growing implementation of genome editing technology.

Growth Drivers:

The increasing prevalence of cancer has created a burden on healthcare systems across the world. According to the World Health Organization (WHO), cancer is one of the biggest causes of death worldwide, with ~10 million deaths in 2020. According to the American Cancer Society, ~1,898,160 new cancer cases and 608,570 cancer deaths occurred in the US in 2021. Nearly 10% to 20% of all cancers are related to gene mutations that are inherited or passed down through the family. Approximately 5–10% of cancers diagnosed in the US are associated with hereditary cancer syndromes. In the US, ~1,958,310 new cancer cases and 609,820 cancer deaths are anticipated to occur in 2023. Additionally, as per the International Agency for Research on Cancer, new cancer incidences were projected to reach 30.2 million by 2040. According to the study titled "Spotlight on Gene Therapy in China," published in July 2020, over 57 million people suffer from genetic diseases in the country, and ~4 million new cancer cases are recorded per year.

The prevalence of genetic diseases is rising across the world and impacting the health of people at a severe level. Most genetic diseases are rare and are developed due to mutations in people's genetic makeup. According to the University of Sheffield research, ~300 million people are living with genetic diseases around the world. In 2022, a report by MJH Life Sciences (US) estimated that 300,000 newborns worldwide are born with sickle cell disease (SCD) every year, accounting for ∼5% of the global population. According to a study on sickle cell disease published in the National Library of Medicine, 400,000 newborns are expected to have sickle cell disease by 2050.

As per the study titled "Sickle Cell Disease," published in August 2023, 1 in 500 African Americans is affected by SCD. In June 2020, as per Novartis AG (Switzerland) report, ∼15,000 individuals were suffering from SCD in the UK, and 270 newborns are diagnosed with the condition every year. In addition, the disease is most prevalent in emerging nations such as India. Among India's tribal communities, ∼18 million people are affected by sickle cell trait (SCT), and 1.4 million people are suffering from SCD.

Many cancer biology investigations are now using clustered regularly interspaced short palindromic repeats (CRISPR) as a standard approach. This technology has also been utilized to enhance the effectiveness and safety profiles of cancer immunotherapy, such as CAR-T cell therapies.

The CRISPR/Cas9 system has been demonstrated to be efficient in treating metastatic tumors, which is a major step toward discovering a cancer cure. The CRISPR-LNP system contains a messenger RNA that encodes for the Cas9 CRISPR enzyme, which is a molecular scissor that cuts the DNA of cells.

Cutting-edge gene editing techniques hold immense promise for tackling dreadful diseases such as SCD. Advancements in technologies such as CRISPR-Cas9 have paved the way for precise and efficient gene editing, allowing the possibility of correcting genetic mutations and modifying disease-causing genes. Thus, the increasing prevalence of cancer and other genetic disorders is expected to boost the gene editing market growth during the forecast period.

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Gene Editing Market: Strategic Insights

gene-editing-market
Market Size Value inUS$ 6,542.95 million in 2022
Market Size Value byUS$ 23,902.34 million by 2030
Growth rateCAGR of 17.6% from 2022 to 2030
Forecast Period2022-2030
Base Year2022
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Report Segmentation and Scope:

The gene editing market is segmented on the basis of component, technology, application, end user, and geography. Based on component, the gene editing market is categorized into reagents and consumables, software and systems, and services. Based on technology, the gene editing market is classified into clustered regularly interspaced short palindromic repeats, transcription activator-like effector nucleases, zinc finger nucleases, and other technologies. The gene editing market, by application, is bifurcated into genetic engineering and clinical applications. Based on end users, the gene editing market is segmented into pharmaceutical companies and biotechnology companies, academics and government research institutes, and clinical research organizations. The gene editing market, based on geography, is segmented into North America (the US, Canada, and Mexico), Europe (France, Germany, the UK, Spain, Italy, and the Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, and the Rest of Asia Pacific, the Middle East & Africa (Saudi Arabia, the UAE, South Africa, and the Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America).

Segmental Analysis:

The gene editing market, by component, is categorized into reagents and consumables, software and systems, and services. The services segment held the largest share of the market in 2022. However, the reagents and consumables segment is expected to register the highest CAGR in the market during 2022–2030.

Based on technology, the gene editing market is segmented into clustered regularly interspaced short palindromic repeats, transcription activator-like effector nucleases, zinc finger nucleases, and other technologies. In 2022, the clustered regularly interspaced short palindromic repeats segment held the largest share of the market, and it is anticipated to record the fastest CAGR during 2022–2030.

Based on application, the gene editing market is bifurcated into genetic engineering and clinical applications. In 2022, the clinical applications segment held a larger share of the market and is anticipated to grow at a higher CAGR during 2022–2030.

Based on end user, the gene editing market is segmented into pharmaceutical companies and biotechnology companies, academics and government research institutes, and clinical research organizations. The pharmaceutical companies and biotechnology companies segment held the largest share of the market in 2022 and is expected to register the highest CAGR during 2022–2030.

Regional Analysis:

The gene editing market is primarily divided into North America, Europe, Asia Pacific, South & Central America, and the Middle East & Africa. In 2022, North America captured a significant share of the market. In 2022, the US held the largest share of the market in the region. The market growth in North America is attributed to the rising investments in the R&D of gene editing technologies, presence of biotechnology and pharmaceutical companies working on the development of genome editing technologies, and increasing product approvals. Moreover, the growing prevalence of genetic disorders and the adoption of advanced gene therapy for the treatment of chronic diseases is estimated to fuel the market growth in the country. For instance, as per the estimates of Cystic Fibrosis Foundation published in July 2022, 40,000 people are living with cystic fibrosis in the US. Furthermore, according to the Centers for Disease Control and Prevention (CDC), ~1,603,844 new cancer cases were diagnosed in 2020, with 602,347 cancer deaths in the US. For every 100,000 individuals, 403 new cancer cases were reported.

In October 2020, Merck signed a licensing agreement with Takara Bio USA, Inc. Merck authorized Takara to use its CRISPR technology to develop vectors and other innovative products to support research using CRISPR and engineering services, particularly stem cells. Thus, such factors support the growth of the market in the region during the forecast period.

Gene Editing Market Report Scope

Industry Developments and Future Opportunities: 

Various initiatives taken by key players operating in the global gene editing market are listed below:

  • In April 2022, Thermo Fisher Scientific introduced the GMP-manufactured Gibco CTS TrueCut Cas9 Protein to help researchers meet stringent quality requirements while using genome editing tools. It is a promising option for CAR T-cell therapy studies using CRISPR-Cas9 genome editing as it consistently provides higher than 90% efficacy in human primary T-cells and high editing effectiveness in all examined cell lines.

Competitive Landscape and Key Companies:

Thermo Fisher Scientific; GenScript; Lonza; Merck KGaA; CRISPR Therapeutics; PerkinElmer Inc.; Agilent Technologies, Inc.; Precision Biosciences; Sangamo Therapeutics, Inc.; New England Biolabs; and Novartis are among the prominent players in the gene editing market. These companies focus on introducing new high-tech products, advancements in existing products, and geographic expansions to meet the growing consumer demand worldwide.

Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Component, Technology, Application, End User, and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


Who are the major players in the gene editing market?

The gene editing market majorly consists of the players, including Thermo Fisher Scientific; GenScript; Lonza; Merck KGaA; CRISPR Therapeutics; PerkinElmer Inc.; Agilent Technologies, Inc.; Precision Biosciences; Sangamo Therapeutics, Inc.; New England Biolabs; and Novartis.

What are the driving and restraining factors for the gene editing market?

The factors driving the growth of the gene editing market include the increase in cancer and other genetic disorders and growing investment in genetic research. However, the high cost of genomic equipment’s hampers the growth of the gene editing market.

What is gene editing?

Gene editing is a scientific method that is used to modify or alter the DNA of living organisms, including plants, bacteria, humans, animals, and others. Gene editing is done for research purposes, the treatment of diseases, and the biotechnological purpose. CRISPR is a genome-editing technology for diagnosing diseases. Gene editing technology has emerged as an effective technique to examine gene function, examine the pathophysiology of hereditary disorders, produce new gene therapeutic targets, breed varieties of crops, and others. Advances in technologies like CRISPR-Cas9 have paved the way for precise and efficient gene editing, enabling the potential to correct genetic mutations and modify disease-causing genes.

What was the estimated gene editing market size in 2022?

The gene editing market was valued at US$ 6,542.95 million in 2022.

What are the growth estimates for the gene editing market till 2030?

The gene editing market is expected to be valued at US$ 23,902.34 million in 2030.

Which segment is dominating the gene editing market?

The global gene editing market is segmented on the basis of components, technology, application, and end users. Based on application, the market is segmented into genetic engineering and clinical applications. The clinical applications segment held a larger share of the market in 2022 and is anticipated to register a higher CAGR during the forecast period.

1. Introduction

1.1 Scope of the Study

1.2 Market Definition, Assumptions and Limitations

1.3 Market Segmentation

2. Executive Summary

2.1 Key Insights

2.2 Market Attractiveness Analysis

3. Research Methodology

4. Gene Editing Market Landscape

4.1 Overview

4.2 PEST Analysis

4.3 Ecosystem Analysis

4.3.1 List of Vendors in the Value Chain

5. Gene Editing Market - Key Market Dynamics

5.1 Key Market Drivers

5.2 Key Market Restraints

5.3 Key Market Opportunities

5.4 Future Trends

5.5 Impact Analysis of Drivers and Restraints

6. Gene Editing Market - Global Market Analysis

6.1 Gene Editing - Global Market Overview

6.2 Gene Editing - Global Market and Forecast to 2030

7. Gene Editing Market – Revenue Analysis (USD Million) – By Technology, 2020-2030

7.1 Overview

7.2 Clustered Regularly Interspaced Short Palindromic Repeats

7.3 Transcription Activator-Like Effector Nucleases

7.4 Zinc Finger Nucleases

7.5 Other Technologies

8. Gene Editing Market – Revenue Analysis (USD Million) – By Component, 2020-2030

8.1 Overview

8.2 Reagents and Consumables

8.3 Software and Systems

8.4 Services

9. Gene Editing Market – Revenue Analysis (USD Million) – By Application, 2020-2030

9.1 Overview

9.2 Clinical Applications

9.3 Genetic Engineering

10. Gene Editing Market – Revenue Analysis (USD Million) – By End User, 2020-2030

10.1 Overview

10.2 Pharmaceutical Companies and Biotechnology Companies

10.3 Academics and Government Research Institutes

10.4 Clinical Research Organizations

11. Gene Editing Market - Revenue Analysis (USD Million), 2020-2030 – Geographical Analysis

11.1 North America

11.1.1 North America Gene Editing Market Overview

11.1.2 North America Gene Editing Market Revenue and Forecasts to 2030

11.1.3 North America Gene Editing Market Revenue and Forecasts and Analysis - By Technology

11.1.4 North America Gene Editing Market Revenue and Forecasts and Analysis - By Component

11.1.5 North America Gene Editing Market Revenue and Forecasts and Analysis - By Application

11.1.6 North America Gene Editing Market Revenue and Forecasts and Analysis - By End User

11.1.7 North America Gene Editing Market Revenue and Forecasts and Analysis - By Countries

11.1.7.1 United States Gene Editing Market

11.1.7.1.1 United States Gene Editing Market, by Technology

11.1.7.1.2 United States Gene Editing Market, by Component

11.1.7.1.3 United States Gene Editing Market, by Application

11.1.7.1.4 United States Gene Editing Market, by End User

11.1.7.2 Canada Gene Editing Market

11.1.7.2.1 Canada Gene Editing Market, by Technology

11.1.7.2.2 Canada Gene Editing Market, by Component

11.1.7.2.3 Canada Gene Editing Market, by Application

11.1.7.2.4 Canada Gene Editing Market, by End User

11.1.7.3 Mexico Gene Editing Market

11.1.7.3.1 Mexico Gene Editing Market, by Technology

11.1.7.3.2 Mexico Gene Editing Market, by Component

11.1.7.3.3 Mexico Gene Editing Market, by Application

11.1.7.3.4 Mexico Gene Editing Market, by End User

Note - Similar analysis would be provided for below mentioned regions/countries

11.2 Europe

11.2.1 Germany

11.2.2 France

11.2.3 Italy

11.2.4 Spain

11.2.5 United Kingdom

11.2.6 Rest of Europe

11.3 Asia-Pacific

11.3.1 Australia

11.3.2 China

11.3.3 India

11.3.4 Japan

11.3.5 South Korea

11.3.6 Rest of Asia-Pacific

11.4 Middle East and Africa

11.4.1 South Africa

11.4.2 Saudi Arabia

11.4.3 U.A.E

11.4.4 Rest of Middle East and Africa

11.5 South and Central America

11.5.1 Brazil

11.5.2 Argentina

11.5.3 Rest of South and Central America

12. Industry Landscape

12.1 Mergers and Acquisitions

12.2 Agreements, Collaborations, Joint Ventures

12.3 New Product Launches

12.4 Expansions and Other Strategic Developments

13. Competitive Landscape

13.1 Heat Map Analysis by Key Players

13.2 Company Positioning and Concentration

14. Gene Editing Market - Key Company Profiles

14.1 Thermo Fisher Scientific Inc.

14.1.1 Key Facts

14.1.2 Business Description

14.1.3 Products and Services

14.1.4 Financial Overview

14.1.5 SWOT Analysis

14.1.6 Key Developments

Note - Similar information would be provided for below list of companies

14.2 Merck KGaA

14.3 Lonza

14.4 GenScript

14.5 CRISPR Therapeutics

14.6 PerkinElmer Inc.

14.7 Agilent Technologies

14.8 Precision BioSciences

14.9 Sangamo Therapeutics Inc.

14.10 New England Biolabs

14.11 Novartis

15. Appendix

15.1 Glossary

15.2 About The Insight Partners

15.3 Market Intelligence Cloud

The List of Companies - Gene Editing Market

  1. Thermo Fisher Scientific
  2. GenScript
  3. Lonza
  4. Merck KGaA
  5. CRISPR Therapeutics
  6. PerkinElmer Inc.
  7. Agilent Technologies Inc.
  8. Precision Biosciences
  9. Sangamo Therapeutics Inc.
  10. New England Biolabs
  11. Novartis

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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