RNAi Therapeutics Market Research Report 2021-2031
The RNAi TherapeuticsMarket was valued at US$ 1.5 billion in 2021 and is expected to reach US$ 3.2 billion by 2031. The market is expected to register a CAGR of 16.5% from 2023–2031. Rising Research & Development (R&D) activity is likely to remain key RNAi Therapeutics Market trends.
RNAi TherapeuticsMarket Analysis
RNAi Therapeutics in Cancer Therapy
RNAi technique is a new modality for cancer therapy, with several candidates being tested clinically. The significant advantage of RNAi for cancer therapy is its high specificity, with an infinite choice of genes that can be applied to cancer therapy. For example, RNAi therapeutics could interfere with angiogenesis, metastasis, chemoresistance of tumors, and proliferation of cancer cells. Additionally, 10 types of RNAi-based cancer therapeutics have entered the early stage clinical trials, demonstrating the potential capability of RNAi with specific gene-silencing efficacy for cancer treatment. Therefore, the aforementioned factors are responsible for influential RNAi therapeutics market growth during 2021-2031.
RNAi TherapeuticsMarket Overview
Technology, innovation, and smart technological solutions such as continue to influence RNAi therapeutics significantly. RNAi therapeutics in cancer therapy and rising clinical trials for developing of innovative RNAi therapeuticsare the most influential factors responsible for RNAi Therapeutics Market growth. Rising Research & Development (R&D) activity is a key trend for RNAi Therapeutics Market growth. Imaging modalities for RNAi therapeuticswill provide lucrative market opportunity.
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RNAi Therapeutics Market: Strategic Insights
Market Size Value in US$ 618.79 Million in 2019 Market Size Value by US$ 1,209.29 Million by 2027 Growth rate CAGR of 8.8% from 2020-2027 Forecast Period 2020-2027 Base Year 2020
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Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
RNAi Therapeutics Market: Strategic Insights
| Market Size Value in | US$ 618.79 Million in 2019 |
| Market Size Value by | US$ 1,209.29 Million by 2027 |
| Growth rate | CAGR of 8.8% from 2020-2027 |
| Forecast Period | 2020-2027 |
| Base Year | 2020 |
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RNAi TherapeuticsMarket Drivers and Opportunities
Rising Clinical Trials for Developing of Innovative RNAi Therapeutics to Favor Market
- In August 2023, Sirnaomics announced "STP707" RNAi therapeutics Clinical Phase 1, which demonstrated promising clinical potential for metastasized tumors. The clinical study was conducted in the US with the participation of multiple leading cancer centers, including Mayo Clinic Oncology, Emory Cancer Center, University of Southern California/Hoag, and Yale Cancer Center.
- Additionally, Alnylam company's has a robust pipeline of investigational RNAi therapeutics to address the needs of patients having limited or inadequate treatment options for disease that include: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases. The products include "ONPATTRO", "AMVUTTRA", "GLVLAARI", "OXLUMO", "Leqvio", "Vutrisiran", "Fitusiran", "Cemdisiran", "Zilebrsiran", "ALN-HSD", "Elebsiran", "Belcesiran", "ALN-APP", "ALN-TTRsc04", "ALN-APP", "ALN-KHK", "ALN-BCAT", "ALN-PNP”.
Therefore, rising clinical trials for RNAi therapeutics will contribute significantly in the coming years.
Imaging Modalities for RNAi Therapeutics for RNAi Therapeutics Market– An Opportunity
Currently, multiple molecular imaging modalities have been applied in RNAi-related research, such as optical imaging (fluorescence and bioluminescence), Magnetic Resonance Imaging (MRI), Magnetic Resonance Spectroscopy (MRS), SPECT, and Positron Emission Tomography (PET). Also, molecular imaging of the therapeutic effects of RNAi is still at the preclinical stage, focussing on the visualization of marker gene expression levels among living animals. These imaging markers are mostly bioluminescent enzymes, where pharmacological activity can be accurately measured. Additionally, MRS also proves useful in evaluating the efficacy of RNAi-based therapies due to its potential to directly detect biological outcomes. Further, the MRS functions better than optical imaging in measuring the chemical shifts to certain compounds (e.g. choline) whose concentration in tissues or tumors can be altered by certain therapeutic interventions. Therefore, R&D activities provide lucrative market opportunities accounting considerable market share in the coming years for RNAi Therapeuticsmarket.
RNAi Therapeutics
Market Report Segmentation Analysis
Key segments that contributed to the derivation of the RNAi Therapeutics Market analysis are candidature and services.
- Based on Molecule Type, the RNAi Therapeutics Market is segmented into Small Interfering RNAs (siRNA) and MicroRNA (miRNA). The Small Interfering RNAs (siRNA) may hold a larger market share in 2023.
- Based on Application, the RNAi Therapeutics Market is segmented into genetic disorders, oncology, neurodegenerative disorders, cardiovascular, respiratory disorders, infectious diseases, renal diseases, and others. The oncology may hold a larger market share in 2023.
- Based on Route of Administration, the RNAi Therapeutics Market is segmented into intradermal injections, pulmonary delivery, intravenous injections, intraperitoneal injections, and others. The pulmonary delivery may hold a larger market share in 2023.
- Based on End User, the RNAi Therapeutics Market is segmented into diagnostic laboratories, research & academic laboratories, and hospitals. The research & academic laboratories may hold a larger market share in 2023.
RNAi Therapeutics Market Share Analysis by Geography
The geographic scope of the RNAi TherapeuticsMarket report is mainly divided into five regions: North America, Asia Pacific, Europe, Middle East & Africa, and South America/South & Central America.
North America has dominated the RNAi Therapeutics Market. In North America, US accounts considerable share for RNAi therapeutics. Presence of top medical biotechnology and pharmaceutical players in the US. Additionally, presence of Contract Research Organizations (CROs) enhancing Research & Development (R&D) activities are one of the most influential factors responsible for market growth. Asia Pacific is anticipated to grow with the highest CAGR in the coming years.
RNAi Therapeutics
Market Report Scope
RNAi TherapeuticsMarket News and Recent Developments
The RNAi TherapeuticsMarket is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. The following is a list of developments in them market for RNAi Therapeutics and strategies:
- In April 2024, Novartis, announced launching of "Leqvio" to maximally tolerated statin therapy, prior to guideline-recommended ezetimibe, in a real-world setting thereby reducing the low-density lipoprotein cholesterol (LDL-C) for patients with atherosclerotic cardiovascular disease (ASCVD).
RNAi TherapeuticsMarket Report Coverage and Deliverables
The “RNAi TherapeuticsMarket Size and Forecast (2021–2031)” report provides a detailed analysis of the market covering below areas:
- Market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Market dynamics such as drivers, restraints, and key opportunities
- Key future trends
- Detailed PEST/Porter’s Five Forces and SWOT analysis
- Global and regional market analysis covering key market trends, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Molecule Type ; Application ; Route of Administration ; End User , and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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