[Research Report] The continuous renal replacement therapy market size is projected to grow from US$ 1.42 billion in 2022 to US$ 2.75 billion by 2030. The market is estimated to register a CAGR of 8.7% from 2022 to 2030.
Market Insights and Analyst View:
This report includes growth prospects owing to the current continuous renal replacement therapy market trends and their foreseeable impact during the forecast period.
Continuous renal replacement therapy (CRRT) is a life-saving intervention for patients suffering severe acute kidney injury (AKI), fluid overload, and uremia with potentially fatal metabolic abnormalities. Factors such as the increased demand for pediatric CRRT devices and the high prevalence of chronic diseases leading to kidney diseases propel the continuous renal replacement therapy market growth. However, a significant chance of a major adverse kidney event (MAKE) limits the market growth.
Market Drivers:
High Incidence of Chronic Diseases Leading to Kidney Diseases
1 in 10 people globally is affected by chronic kidney disease (CKD), which is a common and life-threatening condition. From 2015 to 2019, diabetes and high blood pressure were the two major causes of kidney failure in 75% of the total failure cases. According to estimates released by the National Kidney Foundation in 2020, in the US ~30% of the diabetic population above 20 years of age is at risk of developing CKD in their lifetime. Moreover, this disease caused more deaths than prostate cancer or breast cancer in 2020, and it is an under-recognized emergency health disorder. 1 in 3 American adults (i.e., ~80 million people) is at risk of CKD, which is now identified as a clear risk factor for AKI. Decreased glomerular filtration rate (GFR) and increased proteinuria are strongly associated with an AKI.
According to the National Institute of Health, the occurrence of AKI is rising in developed countries. Its prevalence in hospital inpatients is predicted to reach 15%, and it is higher in critically ill patients i.e., 60%. An AKI incidence in inpatients across the world ranges from 0.7% to 31%; patients in intensive care units (ICUs) experience an incidence of more than 50%. A range from 3% to 13% of patients having AKI need RRT and 40% of these patients are estimated to need CRRT for more than 90 days. Thus, the high prevalence of chronic diseases leading to kidney diseases boosts the continuous renal replacement therapy market growth.
Major ill effects associated with CRRT include hypotension, tachycardia, and other arrhythmias, which may adversely affect the patient's condition or impede their recovery. Furthermore, the CRRT circuit might facilitate the faster clearance of micronutrients, trace elements, and/or therapeutic medicines, which can lead to low or irregular concentrations in blood and tissues, thereby causing adverse effects and/or loss of therapeutic effect. Thus, the adverse effects restrict the continuous renal replacement therapy market.
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Continuous Renal Replacement Therapy Market: Strategic Insights
Market Size Value in US$ 1.42 billion in 2022 Market Size Value by US$ 2.75 billion by 2030 Growth rate CAGR of 8.7% from 2022 to 2030 Forecast Period 2022-2030 Base Year 2022
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Continuous Renal Replacement Therapy Market: Strategic Insights
Market Size Value in | US$ 1.42 billion in 2022 |
Market Size Value by | US$ 2.75 billion by 2030 |
Growth rate | CAGR of 8.7% from 2022 to 2030 |
Forecast Period | 2022-2030 |
Base Year | 2022 |
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Speak to AnalystReport Segmentation and Scope:
The continuous renal replacement therapy market analysis has been carried out by considering the following segments: product, modality, and end user.
Segmental Analysis:
The continuous renal replacement therapy market, by product, is segmented into dialysates and replacement fluids, disposables, bloodline sets and tubes, CRRT systems, and hemofilters. The CRRT systems segment accounted for the largest share of the market in 2022. The hemofilters segment is anticipated to register the highest CAGR in the market during 2022–2030.
By modality, the continuous renal replacement therapy market is segmented into continuous venovenous hemofiltration (CVVH), continuous venovenous hemodiafiltration (CVVHDF), continuous venovenous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF). The continuous venovenous hemofiltration (CVVH) segment held the largest share of the market in 2022. The market for the continuous venovenous hemodiafiltration (CVVHDF) segment is expected to register the highest CAGR during 2022–2030.
By end user, the continuous renal replacement therapy market is segmented into hospitals, ambulatory care centers, home care, and others. In 2022, the hospitals segment dominated the continuous renal replacement therapy market share. However, the home monitoring segment is expected to register the highest CAGR during 2022–2030.
Regional Analysis:
The scope of the continuous renal replacement therapy market report encompasses North America (US, Canada, and Mexico), Europe (Spain, UK, Germany, France, Italy, and Rest of Europe), Asia Pacific (South Korea, China, India, Japan, Australia, and Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, UAE, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).
In terms of revenue, in 2022, North America dominated the continuous renal replacement therapy market share. The market in Asia Pacific is anticipated to register the highest CAGR during 2022–2030. The continuous renal replacement therapy market in Asia Pacific is growing with the improving healthcare infrastructure and the adoption of innovative CRRT technologies, both of which can be associated with rising healthcare expenditure. Additionally, strategic initiatives by the market players to expand their presence in Asia Pacific, such as collaborations with local healthcare providers, favor the market growth in the region.
Continuous Renal Replacement Therapy Market Report Scope
Competitive Landscape and Key Companies:
The continuous renal replacement therapy market report is focused on prominent players in the market such as Baxter International Inc, Asahi Kasei, Fresenius Medical Care, Medica S.p.A., Medtronic Plc, B. Braun, Nikkiso Co Ltd, Toray Medical Co Ltd, Infomed SA, and Quanta Dialysis Technologies Inc. The continuous renal replacement therapy market forecast can help stakeholders plan their growth strategies. These companies focus on launching new technologies, upgrading existing products, and expanding their businesses to meet the growing consumer demand worldwide.
- In April 2022, the US Food and Drug Administration (FDA) provided 510(k) clearance for the ST Set by Baxter International Inc. for its use in continuous renal replacement therapy (CRRT). The ST Set is a pre-connected, disposable, extracorporeal (outside the body) circuit that provides blood purification through a semipermeable membrane to be used with the PrisMax or Prismaflex control units (monitors).
- In March 2022, Nipro Medical Corporation (Nipro), a leading manufacturer and supplier of renal, vascular, and medical-surgical products, announced the commercial launch of the SURDIAL DX Hemodialysis System in the US. SURDIAL DX is a state-of-the-art hemodialysis system designed to create an optimal dialysis treatment experience for patients and clinicians. Manufactured in Japan, the product is based is based on over 35 years of expertise in renal device innovation at Nipro’s parent company, Nipro Corporation.
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Product, Modality, and End User
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
Continuous renal replacement therapy is an available renal replacement method that includes intermittent hemodialysis and peritoneal dialysis to provide renal support for critically ill patients with acute kidney injury, mainly patients who are hemodynamically unstable. It is intended to be applied for 24 hours or longer through continuous, slower dialysis. CRRT is performed through pump-driven venovenous extracorporeal circuits and acts as renal support through blood purification to allow solute and fluid homeostasis.
The continuous renal replacement therapy market majorly consists of players such as Baxter International Inc, Asahi Kasei, Fresenius Medical Care, Medica S.p.A., Medtronic Plc, B. Braun, Nikkiso Co Ltd, Toray Medical Co Ltd, Infomed SA, and Quanta Dialysis Technologies Inc.
US holds the largest market share in continuous renal replacement therapy market According to the Centers for Disease Control and Prevention in 2021, ~785,000 people in the US were living with end-stage kidney disease also known as end-stage renal disease; 71% out of these were undergoing dialysis while 29% had undergone kidney transplant procedures. As of 2020, there were nearly 7,500 dialysis clinics in the US. The increasing adoption of unhealthy food habits is one of the most prominent risk factor for numerous lifestyle-related disorders such as hypertension, diabetes, and kidney dysfunction.
The factors that are driving the growth of the market are the increased demand for pediatric CRRT devices and the high prevalence of chronic diseases leading to kidney diseases.
The continuous renal replacement therapy market, based on product, is segmented into dialysates and replacement fluids, disposables, bloodline sets and tubes, CRRT systems, and hemofilters. The CRRT systems segment held the largest share of the market in 2022.
The continuous renal replacement therapy market, based on modality, is continuous venovenous hemofiltration (CVVH), continuous venovenous hemodiafiltration (CVVHDF), continuous venovenous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF). The continuous venovenous hemofiltration (CVVH) segment held the largest share of the market in 2022; however, the continuous venovenous hemodiafiltration (CVVHDF) segment is likely to register the highest CAGR.
Asia Pacific is expected to be the fastest-growing region in the continuous renal replacement therapy market. Improving healthcare infrastructure with rising expenditure and the adoption of innovative CRRT technologies bolster the continuous renal replacement therapy market size in Asia Pacific. Additionally, strategic initiatives by the market players to expand their presence in this region, including collaborations with local healthcare providers, favor the market growth in the region.
The continuous renal replacement therapy market, based on end user, is segmented into hospitals, ambulatory care centers, home care, and others. In 2022, the hospitals segment dominated the continuous renal replacement therapy market share. The home monitoring segment is expected to register the highest CAGR during 2022–2030.
1. Introduction
1.1 Scope of the Study
1.2 Market Definition, Assumptions and Limitations
1.3 Market Segmentation
2. Executive Summary
2.1 Key Insights
2.2 Market Attractiveness Analysis
3. Research Methodology
4. Continuous Renal Replacement Therapy Market Landscape
4.1 Overview
4.2 PEST Analysis
4.3 Ecosystem Analysis
4.3.1 List of Vendors in the Value Chain
5. Continuous Renal Replacement Therapy Market - Key Market Dynamics
5.1 Key Market Drivers
5.2 Key Market Restraints
5.3 Key Market Opportunities
5.4 Future Trends
5.5 Impact Analysis of Drivers and Restraints
6. Continuous Renal Replacement Therapy Market - Global Market Analysis
6.1 Continuous Renal Replacement Therapy - Global Market Overview
6.2 Continuous Renal Replacement Therapy - Global Market and Forecast to 2030
7. Continuous Renal Replacement Therapy Market – Revenue Analysis (USD Million) – By Product, 2020-2030
7.1 Overview
7.2 Dialysates and Replacement Fluids
7.3 Disposables
7.4 Bloodline Sets and Tubes
7.5 Hemofilters
7.6 CRRT Systems
8. Continuous Renal Replacement Therapy Market – Revenue Analysis (USD Million) – By Modality, 2020-2030
8.1 Overview
8.2 Continuous venovenous hemofiltration (CVVH)
8.3 Continuous venovenous hemodiafiltration (CVVHDF)
8.4 Continuous venovenous hemodialysis (CVVHD)
8.5 Slow continuous ultrafiltration (SCUF)
9. Continuous Renal Replacement Therapy Market – Revenue Analysis (USD Million) – By End User, 2020-2030
9.1 Overview
9.2 Hospital
9.3 Ambulatory care
9.4 Homecare
9.5 Others
10. Continuous Renal Replacement Therapy Market - Revenue Analysis (USD Million), 2020-2030 – Geographical Analysis
10.1 North America
10.1.1 North America Continuous Renal Replacement Therapy Market Overview
10.1.2 North America Continuous Renal Replacement Therapy Market Revenue and Forecasts to 2030
10.1.3 North America Continuous Renal Replacement Therapy Market Revenue and Forecasts and Analysis - By Product
10.1.4 North America Continuous Renal Replacement Therapy Market Revenue and Forecasts and Analysis - By Modality
10.1.5 North America Continuous Renal Replacement Therapy Market Revenue and Forecasts and Analysis - By End User
10.1.6 North America Continuous Renal Replacement Therapy Market Revenue and Forecasts and Analysis - By Countries
10.1.6.1 United States Continuous Renal Replacement Therapy Market
10.1.6.1.1 United States Continuous Renal Replacement Therapy Market, by Product
10.1.6.1.2 United States Continuous Renal Replacement Therapy Market, by Modality
10.1.6.1.3 United States Continuous Renal Replacement Therapy Market, by End User
10.1.6.2 Canada Continuous Renal Replacement Therapy Market
10.1.6.2.1 Canada Continuous Renal Replacement Therapy Market, by Product
10.1.6.2.2 Canada Continuous Renal Replacement Therapy Market, by Modality
10.1.6.2.3 Canada Continuous Renal Replacement Therapy Market, by End User
10.1.6.3 Mexico Continuous Renal Replacement Therapy Market
10.1.6.3.1 Mexico Continuous Renal Replacement Therapy Market, by Product
10.1.6.3.2 Mexico Continuous Renal Replacement Therapy Market, by Modality
10.1.6.3.3 Mexico Continuous Renal Replacement Therapy Market, by End User
Note - Similar analysis would be provided for below mentioned regions/countries
10.2 Europe
10.2.1 Germany
10.2.2 France
10.2.3 Italy
10.2.4 Spain
10.2.5 United Kingdom
10.2.6 Rest of Europe
10.3 Asia-Pacific
10.3.1 Australia
10.3.2 China
10.3.3 India
10.3.4 Japan
10.3.5 South Korea
10.3.6 Rest of SouthEast Asia
10.4 Middle East and Africa
10.4.1 South Africa
10.4.2 U.A.E
10.4.3 Rest of Middle East and Africa
10.5 South and Central America
10.5.1 Brazil
10.5.2 Argentina
10.5.3 Rest of South and Central America
11. Industry Landscape
11.1 Mergers and Acquisitions
11.2 Agreements, Collaborations, Joint Ventures
11.3 New Product Launches
11.4 Expansions and Other Strategic Developments
12. Competitive Landscape
12.1 Heat Map Analysis by Key Players
12.2 Company Positioning and Concentration
13. Continuous Renal Replacement Therapy Market - Key Company Profiles
13.1 Baxter International Inc
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
Note - Similar information would be provided for below list of companies
13.2 Asahi Kasei
13.3 Fresenius Medical Care
13.4 Medica S.p.A.
13.5 Medtronic Plc
13.6 B. Braun
13.7 Nikkiso Co Ltd
13.8 Toray Medical Co Ltd
13.9 Infomed SA
13.10 Quanta Dialysis Technologies Inc
14. Appendix
14.1 Glossary
14.2 About The Insight Partners
14.3 Market Intelligence Cloud
The List of Companies - Continuous Renal Replacement Therapy Market
- Baxter International Inc
- Asahi Kasei
- Fresenius Medical Care
- Medica S.p.A.
- Medtronic Plc
- B. Braun
- Nikkiso Co Ltd
- Toray Medical Co Ltd
- Infomed SA
- Quanta Dialysis Technologies Inc
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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