The enzyme replacement therapy market is expected to grow from US$ 9,673.39 million in 2021 to US$ 15,184.70 million by 2028; it is estimated to grow at a CAGR of 6.8% from 2022 to 2028.
Enzyme replacement therapy (ERT) is performed to treat congenital enzyme deficiencies by using enzyme or protein having enzymatic activity. Animal, human, and recombinant engineered enzymes are a few sources of enzyme required for treatment. The therapy is generally applied in rare and lysosomal storage diseases, including Pompe disease, Fabry disease, Gaucher disease, Tay-Sachs disease, and Hurler syndrome. The most common ERT method is IV infusions, in which the replacement enzyme is administered directly into the bloodstream through a controlled drip of fluids. The growth of the global enzyme replacement therapy market is attributed to the rising prevalence of lysosomal storage diseases (LSDs) and rapid regulatory approval with other marketing benefits for drug with orphan drug designation. However, the cutthroat competition among market players hinders the market growth.
The report offers insights and in-depth analysis of the global enzyme replacement therapy market, emphasizing various parameters including market trends, technological advancements, market dynamics, and competitive landscape analysis of global leading market players. It also includes the impact of the COVID-19 pandemic on the market across all regions. Due to the COVID-19 pandemic, many health authorities focused on pandemic-related care. Moreover, many patients requiring enzyme replacement therapy missed their infusions in March 2020 due to the inadequacy of hospital services dealing with the burden of COVID-19 patients. Patients requiring ERT claimed to feel anxious during hospital admissions or regarding drug supply. Also, studies revealed that some patients had depression and an increased amount of anxiety. Thus, scheduled enzyme replacement therapy (ERT) sessions were disrupted during COVID-19 pandemic leading to a negative impact on the market.
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Enzyme Replacement Therapy Market: Strategic Insights
Market Size Value in US$ 9,673.39 Million in 2021 Market Size Value by US$ 15,184.70 Million by 2028 Growth rate CAGR of 6.8% from 2022 to 2028 Forecast Period 2022-2028 Base Year 2021
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Enzyme Replacement Therapy Market: Strategic Insights
| Market Size Value in | US$ 9,673.39 Million in 2021 |
| Market Size Value by | US$ 15,184.70 Million by 2028 |
| Growth rate | CAGR of 6.8% from 2022 to 2028 |
| Forecast Period | 2022-2028 |
| Base Year | 2021 |
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Geography-Based Insights
By geography, the global enzyme replacement therapy market is segmented into North America (the US, Canada, and Mexico), Europe (France, Germany, the UK, Spain, Italy, and the Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, and the Rest of APAC), the Middle East & Africa (Saudi Arabia, the UAE, South Africa, and the Rest of the MEA), and South & Central America (Brazil, Argentina, and the Rest of South & Central America).
Market Insights
Rising Prevalence of Lysosomal Storage Diseases (LSDs)
A lysosome is a membrane-bound cell organelle that contains digestive enzymes. A lysosome is the key cellular hub for macromolecule catabolism, recycling, and signaling. Any defect in these functions leads to the accumulation or storage of macromolecules in lysosomes, resulting in cellular damage. The leading cause of lysosomal storage diseases (LSDs) is mutations in the genes responsible for encoding a lysosomal enzyme. Additionally, LSDs are characterized as an inborn metabolism error that results in an enzyme's absence or deficiency. Infants and children suffer more severely compared to adults as children can inherit the defective gene from one or both parents. However, since the last decade, the pattern has been changing, and LSDs are more common in adults
Moreover, LSDs are approximately 70 diseases, including Gaucher disease, Niemann-Pick disease, Fabry disease, Tay-Sachs disease, Mucopolysaccharidoses (MPS) diseases, and Pompe disease. These disorders are individually rare, but collectively they are significantly prevalent and affect 1 in 5,000 live births. Many countries conducted surveys to understand the prevalence pattern, and the overall prevalence was rising. For instance, a study published in The Lancet Regional Health entitled "Prevalence of lysosomal storage disorders in Australia from 2009 to 2020". The study revealed the following outcomes:
- The prevalence in the Australian population is 1.6 times (1 per 4,800 live births), higher than the reported prevalence in 1996 (1 per 7,700 live births).
- Fabry disease was most prevalent, representing 34% of all diagnoses (up to 2020).
- LSDs are more common in adulthood than in childhood
Thus, the rising prevalence of LSDs and limited therapies to cure the disease are driving the growth of the global enzyme replacement therapy market
Enzyme Type-Based Insights
Based on enzyme type, the global enzyme replacement therapy market is segmented into alglucosidase alfa, agalsidase beta, imiglucerase, idursulfase, galsulfase, velaglucerase alfa, and other enzymes. In 2021, the other enzymes segment accounted for the largest market share. The same segment is expected to register the highest CAGR in the market from 2022 to 2028.
Therapeutic Conditions-Based Insights
Based on therapeutic conditions, the global enzyme replacement therapy market is segmented into Gaucher's disease, Fabry's Disease, Pompe's Disease, SCID, MPS, and other therapeutic conditions. The Gaucher’s disease segment held the largest market share in 2021 and is expected to register the highest CAGR during the forecast period.
Route of Administration-Based Insights
Based on route of administration, the global enzyme replacement therapy market is bifurcated into parenteral and oral. The parenteral segment held a larger market share in 2021 and is anticipated to register a higher CAGR during the forecast period.
Enzyme Replacement Therapy Market Report Scope
End User-Based Insights
Based on end user, the global enzyme replacement therapy market is segmented into hospitals, infusion centers, and others. The hospitals segment held the largest market share in 2021. However, the infusion centers segment is expected to register the highest CAGR during the forecast period.
The global enzyme replacement therapy market players adopt organic strategies, including product launch and expansion, to expand their footprint and product portfolio worldwide and meet the growing demand. A few major players contributing to the market are Takeda Pharmaceutical Company Limited; Sanofi S.A.; AbbVie Inc.; BioMarin Pharmaceutical Inc.; Amicus Therapeutics; Alexion Pharmaceuticals, Inc. (AstraZeneca); Janssen Pharmaceuticals (Johnson & Johnson Services, Inc.); Recordati S.p.A.; Pfizer Inc.; and CHIESI Farmaceutici S.p.A.
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Enzyme Type, Therapeutic Conditions, Route of Administration, and End-User
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
Global enzyme replacement therapy market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America. In North America, the U.S. is the largest market for enzyme replacement therapy market. A rise in the prevalence of lysosomal storage diseases such as Gaucher’s, Pompe’s, and Fabry’s diseases, increasing regulatory approval, favorable regulatory support by the government, and the availability of various ERT products will drive enzyme replacement therapy market growth in North America. However, the growing government funding for rare disease treatment, increasing clinical trials, an increasing number of product approvals, and expanding partnerships among key players are the key factors responsible for the Asia-Pacific regional growth of the enzyme replacement therapy market accounting fastest growth in the region during the coming years.
The hospitals segment dominated the global enzyme replacement therapy market and accounted for the largest market share of 49.00% in 2021.
Takeda Pharmaceutical Company Limited, Sanofi, AbbVie Inc., BioMarin Pharmaceutical Inc., Amicus Therapeutics, Alexion Pharmaceuticals, Inc.(AstraZeneca), Janssen Pharmaceuticals (Johnson & Johnson Services, Inc.), Recordati S.p.A., Pfizer Inc., and CHIESI Farmaceutici S.p.A. are among the leading companies operating in the enzyme replacement therapy market
Based on route of administration, parenteral route of administration segment took the forefront lead in the worldwide market by accounting largest share in 2021 and is expected to continue to do so till the forecast period.
Based on therapeutic conditions, Gaucher's disease segment took the forefront lead in the worldwide market by accounting largest share in 2021 and is expected to continue to do so till the forecast period.
Based on enzyme type, other enzymes segment took the forefront lead in the worldwide market by accounting largest share in 2021 and is expected to continue to do so till the forecast period. Other enzymes include taliglucerase, laronidase, agalsidase alfa, eliglustat, cipaglucosidase alfa, miglustat, elosulfase alfa, elapegademase, velmanase alfa, pancreatic enzymes, pegademase, sebelipase alfa, cerliponase alfa, among others.
Enzyme replacement therapy (ERT) is a treatment that replaces enzymes that are not present or are deficient in the body. This is usually done by giving the patient an intravenous (IV) infusion or oral solution in which the enzyme is present. ERT is available for various lysosomal storage diseases which include Fabry’s disease, Gaucher’s disease, Pompe’s disease, MPS, and others. The ERT only increases the concentration of the enzymes which is lacking in the patient body and it does not correct any underlying genetic defect. ERT has also been used to treat patients with severe combined immunodeficiency (SCID) resulting from an adenosine deaminase deficiency (ADA-SCID).
Rising prevalence of lysosomal storage diseases (LSDS) and rapid regulatory approval with other benefits for drug with orphan drug designation are the most significant factors responsible for the overall market growth.
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 Global Enzyme Replacement Therapy Market – By Enzyme Type
1.3.2 Global Enzyme Replacement Therapy Market – By Therapeutic Conditions
1.3.3 Global Enzyme Replacement Therapy Market – By Route of Administration
1.3.4 Global Enzyme Replacement Therapy Market – By End User
1.3.5 Global Enzyme Replacement Therapy Market – By Geography
2. Enzyme Replacement Therapy Market– Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Global Enzyme Replacement Therapy Market – Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 North America – PEST Analysis
4.2.2 Europe – PEST Analysis
4.2.3 Asia Pacific – PEST Analysis
4.2.4 Middle East & Africa – PEST Analysis
4.2.5 South & Central America – PEST Analysis
4.3 Expert Opinion
5. Enzyme Replacement Therapy Market – Key Market Dynamics
5.1 Market Drivers
5.1.1 Rising Prevalence of Lysosomal Storage Diseases (LSDs)
5.1.2 Rapid Regulatory Approval with Other Benefits for Drug with Orphan Drug Designation
5.2 Market Restraints
5.2.1 Cutthroat Competition among Market Players
5.3 Market Opportunities
5.3.1 Increasing Partnerships and Collaborations to Synergize the Business
5.4 Future Trends
5.4.1 Innovative Developments in ERT
5.5 Impact Analysis
6. Enzyme Replacement Therapy Market– Global Analysis
6.1 Global Enzyme Replacement Therapy Market Revenue Forecast and Analysis
6.1.1 Global Enzyme Replacement Therapy Market Revenue Forecast and Analysis
6.1.2 Global Enzyme Replacement Therapy Market – Market Potential Analysis, By Region
6.2 Market Share Analysis of Key Players in Enzyme Replacement Therapy Market
6.2.1 Company Analysis
6.2.2 Growth Strategy Analysis
6.2.3 Performance of Key Players
6.2.3.1 Sanofi S.A.
6.2.3.2 BioMarin Pharmaceutical Inc.
7. Global Enzyme Replacement Therapy Market Revenue and Forecasts To 2028– by Enzyme Type
7.1 Overview
7.2 Global Enzyme Replacement Therapy Market, By Enzyme Type 2021 & 2028 (%)
7.3 Alglucosidase Alfa
7.3.1 Overview
7.3.2 Alglucosidase Alfa Revenue and Forecast to 2028 (US$ Million)
7.4 Agalsidase Beta
7.4.1 Overview
7.4.2 Agalsidase Beta - Revenue and Forecast to 2028 (US$ Million)
7.5 Imiglucerase
7.5.1 Overview
7.5.2 Imigluceras - Revenue and Forecast to 2028 (US$ Million)
7.6 Idursulfase
7.6.1 Overview
7.6.2 Idursulfase - Revenue and Forecast to 2028 (US$ Million)
7.7 Galsulfase
7.7.1 Overview
7.7.2 Galsulfase - Revenue and Forecast to 2028 (US$ Million)
7.8 Velaglucerase Alfa
7.8.1 Overview
7.8.2 Velaglucerase Alfa - Revenue and Forecast to 2028 (US$ Million)
7.9 Other Enzymes
7.9.1 Overview
7.9.2 Other Enzymes - Revenue and Forecast to 2028 (US$ Million)
8. Enzyme Replacement Therapy Market Analysis And Forecasts To 2028 – By Therapeutic Conditions
8.1 Overview
8.2 Global Enzyme Replacement Therapy Market, By Therapeutic Conditions 2021 & 2028 (%)
8.3 Gaucher's Disease
8.3.1 Overview
8.3.2 Gaucher's Disease - Market Revenue and Forecast to 2028 (US$ Million)
8.4 Fabry's Disease
8.4.1 Overview
8.4.2 Fabry's Disease - Market Revenue and Forecast to 2028 (US$ Million)
8.5 Mucopolysaccharidosis (MPS)
8.5.1 Overview
8.5.2 MPS - Market Revenue and Forecast to 2028 (US$ Million)
8.6 Pompe's Disease
8.6.1 Overview
8.6.2 Pompe's Disease - Market Revenue and Forecast to 2028 (US$ Million)
8.7 SCID
8.7.1 Overview
8.7.2 SCID - Market Revenue and Forecast to 2028 (US$ Million)
8.8 Other Therapeutic Conditions
8.8.1 Overview
8.8.2 Other Therapeutic Conditions - Market Revenue and Forecast to 2028 (US$ Million)
9. Enzyme Replacement Therapy Market Analysis And Forecasts To 2028 – By Route of Administration
9.1 Overview
9.2 Global Enzyme Replacement Therapy Market, By Route of Administration 2021 & 2028 (%)
9.3 Parenteral
9.3.1 Overview
9.3.2 Parenteral - Market Revenue and Forecast to 2028 (US$ Million)
9.4 Oral
9.4.1 Overview
9.4.2 Oral - Market Revenue and Forecast to 2028 (US$ Million)
10. Global Enzyme Replacement Therapy Market Analysis– By End User
10.1 Overview
10.2 Global Enzyme Replacement Therapy Market, By End User 2021 & 2028 (%)
10.3 Hospitals
10.3.1 Overview
10.3.2 Hospitals - Market Revenue And Forecasts To 2028 (US$ Million)
10.4 Infusion Centers
10.4.1 Overview
10.4.2 Infusion Centers - Market Revenue And Forecasts To 2028 (US$ Million)
10.5 Others
10.5.1 Overview
10.5.2 Others - Market Revenue And Forecasts To 2028 (US$ Million)
11. Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 – Geographical Analysis
11.1 North America: Enzyme Replacement Therapy Market
11.1.1 Overview
11.1.2 North America: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.3 North America: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.1.4 North America: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.1.5 North America: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.6 North America: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.1.7 North America: Enzyme Replacement Therapy Market, by Country, 2021 & 2028 (%)
11.1.7.1 US: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.1.1 Overview
11.1.7.1.2 US: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.1.3 US: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.1.7.1.4 US: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.1.7.1.5 US: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.7.1.6 US: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.1.7.2 Canada: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.2.1 Overview
11.1.7.2.2 Canada: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.2.3 Canada: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.1.7.2.4 Canada: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.1.7.2.5 Canada: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.7.2.6 Canada: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.1.7.3 Mexico: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.3.1 Overview
11.1.7.3.2 Mexico: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.1.7.3.3 Mexico: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.1.7.3.4 Mexico: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.1.7.3.5 Mexico: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.7.3.6 Mexico: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2 Europe: Enzyme Replacement Therapy Market
11.2.1 Overview
11.2.2 Europe: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.3 Europe: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.4 Europe: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.5 Europe: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.6 Europe: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7 Europe: Enzyme Replacement Therapy Market, by Country, 2021 & 2028 (%)
11.2.7.1 Germany: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.1.1 Overview
11.2.7.1.2 Germany: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.1.3 Germany: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.1.4 Germany: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.1.5 Germany: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.1.6 Germany: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7.2 UK: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.2.1 Overview
11.2.7.2.2 UK: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.2.3 UK: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.2.4 UK: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.2.5 UK: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.2.6 UK: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7.3 France: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.3.1 Overview
11.2.7.3.2 France: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.3.3 France: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.3.4 France: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.3.5 France: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.3.6 France: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7.4 Italy: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.4.1 Overview
11.2.7.4.2 Italy: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.4.3 Italy: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.4.4 Italy: Enzyme Replacem4ent Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.4.5 Italy: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.4.6 Italy: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7.5 Spain: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.5.1 Overview
11.2.7.5.2 Spain: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.5.3 Spain: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.5.4 Spain: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.5.5 Spain: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.5.6 Spain: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.2.7.6 Rest of Europe: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.6.1 Overview
11.2.7.6.2 Rest of Europe: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.2.7.6.3 Rest of Europe: Enzyme Replacement Therapy Market, by Enzyme Type, 2019-2028 (US$ Million)
11.2.7.6.4 Rest of Europe: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019-2028 (US$ Million)
11.2.7.6.5 Rest of Europe: Enzyme Replacement Therapy Market, by Route of Administration, 2019-2028 (US$ Million)
11.2.7.6.6 Rest of Europe: Enzyme Replacement Therapy Market, by End User, 2019-2028 (US$ Million)
11.3 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts To 2028
11.3.1 Overview
11.3.2 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.3 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.4 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.5 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.6 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7 Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Country (%)
11.3.7.1 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.1.1 Overview
11.3.7.1.2 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.1.3 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.1.4 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.1.5 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.1.6 Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7.2 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.2.1 Overview
11.3.7.2.2 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.2.3 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.2.4 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.2.5 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.2.6 China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7.3 India Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.3.1 Overview
11.3.7.3.2 India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.3.3 India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.3.4 India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.3.5 India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.3.6 India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7.4 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.4.1 Overview
11.3.7.4.2 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.4.3 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.4.4 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.4.5 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.4.6 Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7.5 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.5.1 Overview
11.3.7.5.2 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
11.3.7.5.3 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.5.4 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.5.5 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.5.6 South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.3.7.6 Rest of Asia Pacific: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.3.7.6.1 Overview
11.3.7.6.2 Rest of Asia Pacific: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
11.3.7.6.3 Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
11.3.7.6.4 Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
11.3.7.6.5 Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
11.3.7.6.6 Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
11.4 South & Central America: Enzyme Replacement Therapy Market
11.4.1 Overview
11.4.2 South and Central America: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.3 South and Central America: Enzyme Replacement Therapy Market, by Enzyme Type, 2019–2028 (USD Million)
11.4.4 South and Central America: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019–2028 (USD Million)
11.4.5 South and Central America: Enzyme Replacement Therapy Market, by Route of Administration, 2019–2028 (USD Million)
11.4.6 South and Central America: Enzyme Replacement Therapy Market, by End User, 2019–2028 (USD Million)
11.4.7 South and Central America: Enzyme Replacement Therapy Market, by country, 2021 & 2028 (%)
11.4.7.1 Brazil: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.1.1 Brazil: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.1.2 Brazil: Enzyme Replacement Therapy Market, by Enzyme Type, 2019–2028 (USD Million)
11.4.7.1.3 Brazil: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019–2028 (USD Million)
11.4.7.1.4 Brazil: Enzyme Replacement Therapy Market, by Route of Administration, 2019–2028 (USD Million)
11.4.7.1.5 Brazil: Enzyme Replacement Therapy Market, by End User, 2019–2028 (USD Million)
11.4.7.2 Argentina: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.2.1 Argentina: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.2.2 Argentina: Enzyme Replacement Therapy Market, by Enzyme Type, 2019–2028 (USD Million)
11.4.7.2.3 Argentina: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019–2028 (USD Million)
11.4.7.2.4 Argentina: Enzyme Replacement Therapy Market, by Route of Administration, 2019–2028 (USD Million)
11.4.7.2.5 Argentina: Enzyme Replacement Therapy Market, by End User, 2019–2028 (USD Million)
11.4.7.3 Rest of South and Central America: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.3.1 Rest of South and Central America: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.4.7.3.2 Rest of South and Central America: Enzyme Replacement Therapy Market, by Enzyme Type, 2019–2028 (USD Million)
11.4.7.3.3 Rest of South and Central America: Enzyme Replacement Therapy Market, by Therapeutic Conditions, 2019–2028 (USD Million)
11.4.7.3.4 Rest of South and Central America: Enzyme Replacement Therapy Market, by Route of Administration, 2019–2028 (USD Million)
11.4.7.3.5 Rest of South and Central America: Enzyme Replacement Therapy Market, by End User, 2019–2028 (USD Million)
11.5 Middle East & Africa Enzyme Replacement Therapy Market
11.5.1 Overview
11.5.2 Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
11.5.3 Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Enzyme Type (US$ Million)
11.5.4 Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Therapeutic Conditions (US$ Million)
11.5.5 Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Route of Administration (US$ Million)
11.5.6 Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by End User (US$ Million)
11.5.7 Middle East & Africa Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Country (%)
11.5.7.1 Saudi Arabia: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.5.7.1.1 Overview
11.5.7.1.2 Saudi Arabia Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
11.5.7.1.3 Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
11.5.7.1.4 Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Therapeutic Conditions (US$ Million)
11.5.7.1.5 Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Route of Administration (US$ Million)
11.5.7.1.6 Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By End User (US$ Million)
11.5.7.2 South Africa: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.5.7.2.1 Overview
11.5.7.2.2 South Africa Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
11.5.7.2.3 South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
11.5.7.2.4 South Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Therapeutic Conditions (US$ Million)
11.5.7.2.5 South Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Route of Administration (US$ Million)
11.5.7.2.6 South Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By End User (US$ Million)
11.5.7.3 UAE: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.5.7.3.1 Overview
11.5.7.3.2 UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
11.5.7.3.3 UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
11.5.7.3.4 UAE: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Therapeutic Conditions (US$ Million)
11.5.7.3.5 UAE: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Route of Administration (US$ Million)
11.5.7.3.6 UAE: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By End User (US$ Million)
11.5.7.4 Rest of the Middle East and Africa: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
11.5.7.4.1 Overview
11.5.7.4.2 Rest of the Middle East and Africa Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
11.5.7.4.3 Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
11.5.7.4.4 Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Therapeutic Conditions (US$ Million)
11.5.7.4.5 Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By Route of Administration (US$ Million)
11.5.7.4.6 Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast To 2028, By End User (US$ Million)
12. Impact Of COVID-19 Pandemic on Enzyme Replacement Therapy Market
12.1 North America: Impact Assessment of COVID-19 Pandemic
12.2 Europe: Impact Assessment of COVID-19 Pandemic
12.3 Asia-Pacific: Impact Assessment of COVID-19 Pandemic
12.4 South and Central America: Impact Assessment of COVID-19 Pandemic
12.5 Middle East and Africa: Impact Assessment of COVID-19 Pandemic
13. Enzyme Replacement Therapy Market–Industry Landscape
13.1 Overview
13.2 Growth Strategies in the Enzyme Replacement Therapy Market
13.3 Inorganic Growth Strategies
13.3.1 Overview
13.4 Organic Growth Strategies
13.4.1 Overview
14. Company Profiles
14.1 Takeda Pharmaceutical Company Limited
14.1.1 Key Facts
14.1.2 Business Description
14.1.3 Products and Services
14.1.4 inancial Overview
14.1.5 SWOT Analysis
14.1.6 Key Developments
14.2 Sanofi
14.2.1 Key Facts
14.2.2 Business Description
14.2.3 Products and Services
14.2.4 Financial Overview
14.2.5 SWOT Analysis
14.2.6 Key Developments
14.3 AbbVie Inc.
14.3.1 Key Facts
14.3.2 Business Description
14.3.3 Products and Services
14.3.4 Financial Overview
14.3.5 SWOT Analysis
14.3.6 Key Developments
14.4 BioMarin Pharmaceutical Inc.
14.4.1 Key Facts
14.4.2 Business Description
14.4.3 Products and Services
14.4.4 Financial Overview
14.4.5 SWOT Analysis
14.4.6 Key Developments
14.5 Amicus Therapeutics
14.5.1 Key Facts
14.5.2 Business Description
14.5.3 Products and Services
14.5.4 Financial Overview
14.5.5 SWOT Analysis
14.5.6 Key Developments
14.6 Alexion Pharmaceuticals, Inc.(AstraZeneca)
14.6.1 Key Facts
14.6.2 Business Description
14.6.3 Products and Services
14.6.4 Financial Overview
14.6.5 WOT Analysis
14.6.6 Key Developments
14.7 Janssen Pharmaceuticals (Johnson & Johnson Services, Inc.)
14.7.1 Key Facts
14.7.2 Business Description
14.7.3 Products and Services
14.7.4 Financial Overview
14.7.5 SWOT Analysis
14.7.6 Key Developments
14.8 Recordati S.p.A.
14.8.1 Key Facts
14.8.2 Business Description
14.8.3 Products and Services
14.8.4 Financial Overview
14.8.5 SWOT Analysis
14.8.6 Key Developments
14.9 Pfizer Inc.
14.9.1 Key Facts
14.9.2 Business Description
14.9.3 Products and Services
14.9.4 Financial Overview
14.9.5 SWOT Analysis
14.9.6 Key Developments
14.10 CHIESI Farmaceutici S.p.A.
14.10.1 Key Facts
14.10.2 Business Description
14.10.3 Products and Services
14.10.4 Financial Overview
14.10.5 SWOT Analysis
14.10.6 Key Developments
15. Appendix
15.1 About The Insight Partners
15.2 Glossary of Terms
LIST OF TABLES
Table 1. North America Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 2. North America Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 3. North America Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 4. North America Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 5. US: Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 6. US Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 7. US Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 8. US Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 9. Canada Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 10. Canada Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 11. Canada Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 12. Canada Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 13. Mexico Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 14. Mexico Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 15. Mexico Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 16. Mexico Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (US$ Million)
Table 17. Europe Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 18. Europe Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 19. Europe Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 20. Europe Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 21. Germany Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 22. Germany Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 23. Germany Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 24. Germany Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 25. UK Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 26. UK Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 27. UK Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 28. UK Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 29. France Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 30. France Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 31. France Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 32. France Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 33. Italy Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 34. Italy Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 35. Italy Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 36. Italy Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 37. Spain Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 38. Spain Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 39. Spain Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 40. Spain Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 41. Rest of Europe Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (US$ Million)
Table 42. Rest of Europe Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 43. Rest of Europe Enzyme Replacement Therapy Market, by Route of Administration – Revenue and Forecast to 2028 (USD Million)
Table 44. Rest of Europe Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 45. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million).
Table 46. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 47. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 48. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 49. Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 50. Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 51. Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 52. Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 53. China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 54. China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 55. China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 56. China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 57. India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 58. India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 59. India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 60. India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 61. Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 62. Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 63. Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 64. Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 65. South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 66. South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 67. South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 68. South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 69. Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Enzyme Type (US$ Million)
Table 70. Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Therapeutic Conditions (US$ Million)
Table 71. Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Route of Administration (US$ Million)
Table 72. Rest of Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By End User (US$ Million)
Table 73. South and Central America: Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (USD Million)
Table 74. South and Central America: Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 75. South and Central America: Enzyme Replacement Therapy Market, by Route of Administration– Revenue and Forecast to 2028 (USD Million)
Table 76. South and Central America: Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 77. Brazil: Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (USD Million)
Table 78. Brazil: Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 79. Brazil: Enzyme Replacement Therapy Market, by Route of Administration– Revenue and Forecast to 2028 (USD Million)
Table 80. Brazil: Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 81. Argentina: Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (USD Million)
Table 82. Argentina: Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 83. Argentina: Enzyme Replacement Therapy Market, by Route of Administration– Revenue and Forecast to 2028 (USD Million)
Table 84. Argentina: Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 85. Rest of South and Central America: Enzyme Replacement Therapy Market, by Enzyme Type – Revenue and Forecast to 2028 (USD Million)
Table 86. Rest of South and Central America: Enzyme Replacement Therapy Market, by Therapeutic Conditions – Revenue and Forecast to 2028 (USD Million)
Table 87. Rest of South and Central America: Enzyme Replacement Therapy Market, by Route of Administration– Revenue and Forecast to 2028 (USD Million)
Table 88. Rest of South and Central America: Enzyme Replacement Therapy Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 89. Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Enzyme Type (US$ Million)
Table 90. Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Therapeutic Conditions (US$ Million)
Table 91. Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Route of Administration (US$ Million)
Table 92. Middle East & Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by End User (US$ Million)
Table 93. Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
Table 94. Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Therapeutic Conditions (US$ Million)
Table 95. Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Route of Administration (US$ Million)
Table 96. Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By End User (US$ Million)
Table 97. South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
Table 98. South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Therapeutic Conditions (US$ Million)
Table 99. South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Route of Administration (US$ Million)
Table 100. South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By End User (US$ Million)
Table 101. UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
Table 102. UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Therapeutic Conditions (US$ Million)
Table 103. UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Route of Administration (US$ Million)
Table 104. UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By End User (US$ Million)
Table 105. Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Enzyme Type (US$ Million)
Table 106. Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Therapeutic Conditions (US$ Million)
Table 107. Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By Route of Administration (US$ Million)
Table 108. Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028, By End User (US$ Million)
Table 109. Recent Inorganic Growth Strategies in the Enzyme Replacement Therapy Market
Table 110. Recent Organic Growth Strategies in the Enzyme Replacement Therapy Market
Table 111. Glossary of Terms
LIST OF FIGURES
Figure 1. Enzyme Replacement Therapy Market Segmentation
Figure 2. Enzyme Replacement Therapy Market Segmentation, By Region
Figure 3. Global Enzyme Replacement Therapy Market Overview
Figure 4. Others Enzyme Segment Held Largest Share by Enzyme Type in Enzyme Replacement Therapy Market
Figure 5. Asia-Pacific Region Is Expected to Show Remarkable Growth During the Forecast Period
Figure 6. Global Enzyme Replacement Therapy Market, By Geography (US$ Million)
Figure 7. Global Enzyme Replacement Therapy Market - Leading Country Markets (US$ Million)
Figure 8. Global Enzyme Replacement Therapy Market, Industry Landscape
Figure 9. North America: PEST Analysis
Figure 10. Europe: PEST Analysis
Figure 11. Asia Pacific: PEST Analysis
Figure 12. Middle East & Africa: PEST Analysis
Figure 13. South & Central America: PEST Analysis
Figure 14. Impact Analysis
Figure 15. Global Enzyme Replacement Therapy Market– Revenue Forecast and Analysis – 2020- 2028
Figure 16. Global Enzyme Replacement Therapy Market– Revenue Forecast And Analysis – 2021 - 2028
Figure 17. Global Enzyme Replacement Therapy Market – Market Potential Analysis, By Region
Figure 18. Market Share Analysis of Key Players in Global Enzyme Replacement Therapy Market
Figure 19. Global Enzyme Replacement Therapy Market – Comparative Company Analysis
Figure 20. Global Enzyme Replacement Therapy Market – Growth Strategy Analysis
Figure 21. Market positioning of Key Players in Enzyme Replacement Therapy Market
Figure 22. Global Enzyme Replacement Therapy Market, by Enzyme Type 2021 & 2028 (%)
Figure 23. Alglucosidase Alfa Revenue and Forecasts to 2028 (US$ Million)
Figure 24. Agalsidase Beta - Revenue and Forecasts to 2028 (US$ Million)
Figure 25. Imiglucerase - Revenue and Forecasts to 2028 (US$ Million)
Figure 26. Idursulfase - Revenue and Forecasts to 2028 (US$ Million)
Figure 27. Galsulfase - Revenue and Forecasts to 2028 (US$ Million)
Figure 28. Velaglucerase Alfa - Revenue and Forecasts to 2028 (US$ Million)
Figure 29. Other Enzymes - Revenue and Forecasts to 2028 (US$ Million)
Figure 30. Global Enzyme Replacement Therapy Market, by Therapeutic Conditions 2021 & 2028 (%)
Figure 31. Gaucher's Disease - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 32. Fabry's Disease - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 33. MPS - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 34. Pompe's Disease - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 35. SCID - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 36. Other Therapeutic Conditions - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 37. Global Enzyme Replacement Therapy Market, by Route of Administration 2021 & 2028 (%)
Figure 38. Parenteral - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 39. Oral - Market Revenue and Forecasts to 2028 (US$ Million)
Figure 40. Global Enzyme Replacement Therapy Market, by End User 2021 & 2028 (%)
Figure 41. Hospitals - Market Revenue And Forecasts To 2028 (US$ Million)
Figure 42. Infusion Centers - Market Revenue And Forecasts To 2028 (US$ Million)
Figure 43. Others- Market Revenue And Forecasts To 2028 (US$ Million)
Figure 44. North America: Enzyme Replacement Therapy Market, by Key Country – Revenue (2021) (US$ Million)
Figure 45. North America Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 46. North America: Enzyme Replacement Therapy Market, by Country, 2021 & 2028 (%)
Figure 47. US: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 48. Canada: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 49. Mexico: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 50. Europe: Enzyme Replacement Therapy Market, by Key Country – Revenue (2021) (US$ Million)
Figure 51. Europe: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 52. Europe: Enzyme Replacement Therapy Market, by Country, 2021 & 2028 (%)
Figure 53. Germany: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 54. UK: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 55. France: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 56. Italy: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 57. Spain: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 58. Rest of Europe: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 59. Asia Pacific: Enzyme Replacement Therapy Market Overview, by Country (2021)
Figure 60. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 61. Asia Pacific: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028, By Country (%)
Figure 62. Japan: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 63. China: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 64. India: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 65. Australia: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 66. South Korea: Enzyme Replacement Therapy Market Revenue and Forecasts to 2028 (US$ Million)
Figure 67. Rest of Asia Pacific: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (US$ Million)
Figure 68. South and Central America: Enzyme Replacement Therapy Market, by Key Country – Revenue (2021) (US$' Million)
Figure 69. South and Central America Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (USD Million)
Figure 70. South and Central America: Enzyme Replacement Therapy Market, by country, 2021 & 2028 (%)
Figure 71. Brazil: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
Figure 72. Argentina: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
Figure 73. Rest of South and Central America: Enzyme Replacement Therapy Market – Revenue and Forecast to 2028 (USD Million)
Figure 74. Middle East & Africa Enzyme Replacement Therapy Market Revenue Overview, by Country, 2021 (US$ Million)
Figure 75. Middle East & Africa Enzyme: Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 76. Middle East & Africa Enzyme Replacement Therapy Market Revenue and Forecast to 2028, by Country (%)
Figure 77. Saudi Arabia: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 78. South Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 79. UAE: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 80. Rest of the Middle East and Africa: Enzyme Replacement Therapy Market Revenue and Forecast to 2028 (US$ Million)
Figure 81. Impact of COVID-19 Pandemic in North American Country Markets
Figure 82. Impact of COVID-19 Pandemic in European Country Markets
Figure 83. Impact of COVID-19 Pandemic in Asia Pacific Country Markets
Figure 84. Impact of COVID-19 Pandemic in South and Central American Countries
Figure 85. Impact of COVID-19 Pandemic in Middle East and Africa Country Markets
Figure 86. Growth Strategies in the Enzyme Replacement Therapy Market
The List of Companies - Enzyme Replacement Therapy Market
- Sanofi
- BioMarin Pharmaceutical Inc.
- Takeda Pharmaceutical Company Limited
- AbbVie Inc.
- Janssen Pharmaceuticals (Johnson & Johnson Services, Inc.)
- Alexion Pharmaceuticals, Inc (AstraZeneca)
- Amicus Therapeutics
- Recordati S.p.A.
- CHIESI Farmaceutici S.p.A.
- Pfizer Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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