Osteoporosis Treatment Market Size and Share Outlook 2031

The osteoporosis treatment market size is projected to surge from US$ 16.83 billion in 2023 to US$ 22.72 billion by 2031; the market is estimated to record a CAGR of 3.8% during 2023–2031.

Analyst Perspective:

The report includes growth prospects owing to the current osteoporosis treatment market trends and their foreseeable impact during the forecast period. Osteoporosis can cause bones to become brittle to an extent that a minor fall can result in fractures, thereby affecting the quality of life. Early detection and treatment help in slowing or even stopping the progression of osteoporosis, in turn, reducing the risk of fractures. Thus, the prevalence of osteoporosis increases the need for diagnosis, which subsequently boosts the growth of the osteoporosis treatment market. Osteoporosis is mainly observed in women due to hormonal changes at menopause that affect the bone density. Apart from hormonal changes, other factors that increase the risk of osteoporosis in aging individuals are rheumatoid arthritis, a family history of osteoporosis, and long-term use of medications that affect bone strength. According to the International Osteoporosis Foundation, of the majority of people who have osteoporosis, 25% are women and 5% are men aged over 65.

Market Overview:

Osteoporosis is a progressive disease associated with high-risk fractures in men, postmenopausal women, and the geriatric population. Osteoporosis patients are particularly prone to bone, hip, forearm, spine, and wrist fractures. Therefore, it is described as a metabolic disease that lowers bone mineral density and leads to bone fractures. The therapeutic arsenal often includes bisphosphonates, hormone therapy, denosumab, and a range of nutritional supplements recommended along with lifestyle adjustments such as increased physical activity and a calcium-rich diet. Key factors driving the osteoporosis treatment market growth include an increase in healthcare spending on discovery and drug development and increasing awareness about available drugs for the treatment of osteoporosis.

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Osteoporosis Treatment Market: Strategic Insights

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Market Driver:

Increasing Cases of Osteoporosis and Modifications in Lifestyle Propel Market Growth

The prevalence of osteoporosis is increasing worldwide, largely due to improper lifestyle, poor diet, lack of exercise, inadequate calcium and vitamin D intake, and hormonal imbalance. As per the International Osteoporosis Foundation, more than 8.9 million fractures are caused because of osteoporosis annually, resulting in one osteoporotic fracture every three seconds, and it is estimated that it affects 200 million women worldwide. The increasing geriatric population is also an important factor driving the osteoporosis treatment market growth. According to a study published in Labiotech, "Advancements in Osteoporosis Research," about 10 million Americans have osteoporosis. ~44 million people have low bone density, putting them at an increased risk of osteoporosis. The risk of developing osteoporosis significantly increases with age; it is estimated that adults aged 50 and above are at high risk of fracture. Three-quarters of adults aged 65 and older suffering from hip fractures annually in the US are women, and it is estimated that around 15–36% of hip fracture patients die within a year. A broader emphasis on holistic health and wellness encourages the adoption of regular health screenings, including bone density scans. As individuals proactively monitor their bone health, early diagnosis and interventions are becoming increasingly important, further stimulating the expansion of the market. The osteoporosis treatment market is receiving significant impetus from increasing awareness about bone health, which drives the demand for preventive and therapeutic solutions.

Segmental Analysis:

The osteoporosis treatment market analysis has been carried out by considering the following segments: drug class, type, route of administration, and distribution channel.

Based on drug class, the osteoporosis treatment market is segmented into RANKL, bisphosphonates, selective estrogen receptor modulators (SERM), hormone therapies, and others. The RANKL segment held the largest market share in 2023. However, the hormone therapies segment is estimated to register the highest CAGR during 2023–2031. The bisphosphonates segment also holds a considerable share in the osteoporosis treatment market. Bisphosphonates, which include compounds such as alendronate and zoledronic acid, have proven to be effective in inhibiting bone resorption, increasing bone density, and minimizing the risk of fractures. Their extensive clinical history, regulatory approvals, and availability of oral and intravenous formulations make them the preferred choice by healthcare professionals. Furthermore, their cost-effectiveness and comprehensive insurance coverage contribute to their wide adoption in the osteoporosis treatment market.

The market, based on type, is bifurcated into primary osteoporosis and secondary osteoporosis. The primary osteoporosis segment held a larger osteoporosis treatment market share in 2023. Primary osteoporosis occurs with aging, which results in slow bone renewal. According to a study published in the National Library of Medicine titled “Prevalence of Primary Osteoporosis and Low Bone Mass in Postmenopausal Women and Associated Risk Factors,” 30% of women aged over 50 have osteoporosis worldwide. 8–9% of bone fractures per year are known to be caused by osteoporosis. In addition, men and women aged 70 years and above experience an imbalance between bone formation and loss, leading to back pain, reduced quality of life, and impairment of daily activities.

Based on the route of administration, the osteoporosis treatment market is bifurcated into oral and injectable. The injectable segment held the largest osteoporosis treatment market share in 2023. The injectable segment is anticipated to register the highest CAGR during 2023–2031. The dominant presence of the injectable segment in the market can be attributed to its effectiveness and reliability as a drug delivery method. Administering treatment through injections ensures direct entry of the drug into the bloodstream, resulting in rapid and predictable absorption, which is a key advantage in the treatment of osteoporosis. Additionally, certain osteoporosis medications are available only in injectable form, further promoting its market share. With improving patient compliance for self-administered injections and the continued development of innovative drug delivery solutions, the injectable segment is poised to maintain its strong market position.

Regional Analysis:

The scope of the osteoporosis treatment market report includes North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. The market in North America was valued at US$ 8.26 billion in 2023 and is projected to reach US$ 11.26 billion by 2031; it is expected to register a CAGR of 3.9% during 2023–2031. One of the key factors driving the market growth in this region is the significant aging population in the region, with greater awareness of osteoporosis. Second, advanced healthcare infrastructure and comprehensive access to medical services enable timely diagnosis and treatment. In addition, the presence of large pharmaceutical companies and ongoing research and development initiatives are encouraging the introduction of innovative therapies. Finally, favorable reimbursement policies and insurance coverage support patients seeking osteoporosis treatment, promoting the osteoporosis treatment market in North America.

The Asia Pacific osteoporosis treatment market is expected to record the highest CAGR of 4.7%. The region, especially with countries such as India and China, is home to a sizable pharmaceutical industry. China is a pharmaceutical manufacturing hub. The projected market growth in this region is attributed to the growing middle class and increased accessibility to healthcare. Additionally, improvements in healthcare infrastructure and the emerging pharmaceutical sector make the Asia Pacific a hub for the significant growth and development of the osteoporosis treatment market.

Osteoporosis Treatment Market Report Scope

Key Player Analysis:

Pfizer Inc.; Amgen Inc.; Cadila Pharmaceuticals; Eli Lilly and Company; Daiichi Sankyo Company, Limited; Teva Pharmaceuticals Inc.; Asahi Kasei Corporation; Novartis AG; Chugai Pharmaceutical Co., Ltd.; and Teijin Pharma Limited are among the key players profiled in the osteoporosis treatment market report.

Recent Developments:

Companies operating in the osteoporosis treatment market adopt mergers and acquisitions as key growth strategies. As per company press releases, a few recent market developments are listed below:

• In October 2021, Entera Bio, a leading biotechnology company, released key data for its mid-stage oral osteoporosis drug formulation study. The company has advanced Phase 3 registration of this study.
• In August 2021, the Drug Controller General of India (DCGI) gave Marketing Authorization (MA) to Enzene Biosciences Ltd, for its biosimilar drug Denosumab, which is indicated for treating osteoporosis in adults.
• In January 2021, Theramex, a pharmaceutical company headquartered in London, launched the osteoporosis drug Livogiva in Europe.