The small molecule drug discovery market size is projected to reach US$ 106.77 billion by 2031 from US$ 50.93 billion in 2023. The market is expected to register a CAGR of 9.7% during 2023–2031. The growing adoption of artificial intelligence in drug discovery is likely to act as a future trend in the market.
Small Molecule Drug Discovery Market Analysis
The small molecule drug discovery market is mainly driven by increasing R&D by pharmaceutical and biotechnology companies in discovering novel drugs, government initiatives, and the prevalence of cancer. Other factors contributing to the market expansion include the globalization of clinical trials, rapid advancements in associated technologies, and an increase in demand for CROs for conducting clinical trials. In addition, increasing small molecule-based pipeline acts as an opportunity for the growth of the small molecule drug discovery market.
Small Molecule Drug Discovery Market Overview
Asia Pacific is expected to register the highest CAGR during the forecast period. An upsurge in technological advancements, a surge in collaborations (for the development of genomic research) among Asian and Western countries, a decrease in prices of DNA sequencing, and a rising prevalence of genetic and other target diseases are propelling the Asia Pacific small molecule drug discovery market. The market in Asia Pacific is expected to propel owing to the rising GDP resulting in the growth of the pharmaceutical industry. Additionally, the increasing disposable income is boosting the adoption of advanced healthcare techniques. Thus, there is a huge potential for the small molecule drug discovery market owing to the aforementioned factors.
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Small Molecule Drug Discovery Market: Strategic Insights
Market Size Value in US$ 24,976.14 Million in 2019 Market Size Value by US$ 50,823.06 Million by 2027 Growth rate CAGR of 9.5% from 2020-2027 Forecast Period 2020-2027 Base Year 2020
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Small Molecule Drug Discovery Market: Strategic Insights
| Market Size Value in | US$ 24,976.14 Million in 2019 |
| Market Size Value by | US$ 50,823.06 Million by 2027 |
| Growth rate | CAGR of 9.5% from 2020-2027 |
| Forecast Period | 2020-2027 |
| Base Year | 2020 |
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Small Molecule Drug Discovery Market Drivers and Opportunities
Flourishing Pharmaceutical Industry with Surge in R&D Activities
The pharmaceutical industry is one of the most R&D-intensive industries in the world. Efforts are being made to achieve greater effectiveness and efficiency in fulfilling patients' needs. The cost of medicines has been a prime concern for pharmaceutical companies as they bank on their R&D activities to achieve intended cost targets. Over the last decade, the number of new small molecule drugs approved yearly has drastically increased. The Food and Drug Administration (FDA) approved 55 new drugs in 2023. The small molecules dominated new drug approvals in 2023, accounting for 62% of all new molecular entities (NME) approved. Globally, the US is a leading country in terms of R&D investments, and the country produced over 50% of the world's new molecules in the past decade. An increase in approval has led to growing investments by companies for the development of small molecule drugs due to their potential in treating several severe diseases.
R&D Investments by Major Pharmaceutical Companies
Company | 2022 (US$ Billion) | 2023 (US$ Billion) |
Takeda Pharmaceutical Co Ltd | 4.2 | 5.08 |
Pfizer Inc | 11.4 | 10.6 |
Grifols SA | 427.05 | 432.71 |
Note: The current conversion rate is considered for presenting the currencies.
Source: Annual Reports and The Insight Partners Analysis
The R&D expenditure is instrumental in companies' efforts to discover, examine, and produce new products; make upfront payments; improve existing outcomes; and demonstrate product efficacy and regulatory compliance before launch. These investments differ as per the need and demand for drug discovery. The cost includes materials, supplies used, and employee salaries, along with the cost of developing quality control. According to PhRMA Member Companies 2021 report, the top 15 largest pharmaceutical companies by revenue invested US$ 133 billion in R&D cumulatively, and ~44% of the total R&D investment was allocated to drug discovery. Thus, the increasing R&D investments by companies are fueling the small molecule drug discovery market growth.
Increasing Small Molecule-Based Pipeline to Offer Opportunity for Market Growth
The pharmaceutical industry is continually evolving and there is always a need for new, innovative therapeutic approaches in the treatment of various chronic indications. Small molecule-based drug approvals have increased over the past five years owing to their effectiveness against a wide range of indications. Small molecule drug candidate-based pipelines are growing for a wide range of therapeutic applications, including oncology, hypertension, diabetes, and inflammatory disorders. Many big and small pharmaceutical companies are engaged in the development of several small-molecule drugs.
The growing pipeline of small molecule-based drugs for various indications is, in turn, boosting drug discovery activities across the industry.
Compound Name | Compound Type | Company Name | Clinical Phase | Indication |
PF-06821497 | Small Molecule | Pfizer Inc. | Phase 1 | Cancer |
PF-06873600 | Small Molecule | Pfizer Inc. | Phase 1 | Breast Cancer Metastatic |
PF-06939999 | Small Molecule | Pfizer Inc. | Phase 1 | Solid Tumors |
PF-06952229 | Small Molecule | Pfizer Inc. | Phase 1 | Cancer |
PF-06826647 | Small Molecule | Pfizer Inc. | Phase 1 | Ulcerative Colitis |
PF-07038124 | Small Molecule | Pfizer Inc. | Phase 1 | Atopic Dermatitis |
PF-06842874 | Small Molecule | Pfizer Inc. | Phase 1 | Pulmonary Arterial Hypertension |
PF-06865571 | Small Molecule | Pfizer Inc. | Phase 1 | Non-alcoholic Steatohepatitis (NASH) with Liver Fibrosis |
PF-06882961 | Small Molecule | Pfizer Inc. | Phase 1 | Diabetes Mellitus-Type 2, Obesity |
PF-07081532 | Small Molecule | Pfizer Inc. | Phase 1 | Diabetes Mellitus-Type 2, Obesity |
R835 | Small Molecule | Rigel Pharmaceuticals, Inc. | Phase 1 | Inflammatory Disorders |
R552 | Small Molecule | Rigel Pharmaceuticals, Inc. | Phase 1 | Inflammatory Disorders |
SY-1425 | Small Molecule | Syros Pharmaceuticals, Inc. | Phase 2 | AML |
Source: Company News and The Insight Partner Analysis
Small Molecule Drug Discovery Market Report Segmentation Analysis
Key segments that contributed to the derivation of the small molecule drug discovery market analysis are therapeutic area and process/phase.
- Based on therapeutic area, the small molecule drug discovery market is segmented into oncology, central nervous system, cardiovascular, respiratory, orthopedics, immunology, rare diseases, and other therapeutic areas. The oncology segment held the largest share of the market in 2023.
- By process/phase, the market is segmented into target discovery, target validation, lead generation and refinement, and preclinical development. The lead generation and refinement segment dominated the market in 2023.
Small Molecule Drug Discovery Market Share Analysis by Geography
The geographic scope of the small molecule drug discovery market report is mainly divided into five regions: North America, Asia Pacific, Europe, South & Central America, and the Middle East & Africa. In terms of revenue, North America dominated the market in 2023. Increasing research and development by pharmaceutical and biotechnology companies in discovering novel drugs, growing investments in pharmaceuticals, and prevalence of cancer are among the factors that are projected to accelerate the growth of the North America small molecule drug discovery market. The US is the largest and fastest-growing market for small molecule drug discovery. The increasing prevalence of chronic diseases such as cardiovascular diseases and cancer primarily drives the market growth in the country. As per the American Cancer Society, in 2024, ~2 million people are projected to suffer from new cancer cases, and ~611,000 death cases are expected to be registered in the US. Owing to this scenario, the US health system witnesses massive investments in research and developments for novel drug molecules. Further, a strong drug pipeline, along with therapeutic area approvals for small molecule drugs, is expected to drive the regional market. Apart from the rising number of approved drugs, increasing awareness of advanced therapeutics is likely to be responsible for the growth of the small molecule drug discovery market during the forecast period.
Small Molecule Drug Discovery Market Report Scope
Small Molecule Drug Discovery Market News and Recent Developments
The small molecule drug discovery market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. A few of the developments in the market are listed below:
- Oncodesign Services (ODS) acquired ZoBio, a Dutch CRO expert in biophysics-based small molecule drug discovery. This acquisition allows ODS to strengthen and extend its expertise and capabilities in the field of small molecule discovery to a fully integrated offering to support its customers' innovative programs from target validation to candidate selection. (Source: Oncodesign Services, Company Website, January 2024)
- Merck entered into new strategic drug discovery collaborations aimed at harnessing powerful artificial intelligence (AI)-driven design and discovery capabilities, further advancing the company’s research efforts. The partnership of BenevolentAI (London, UK) and Exscientia (Oxford, UK) is expected to generate several novel clinical development drug candidates with first-in-class and best-in-class potential in key therapeutic areas of oncology, neurology, and immunology. (Source: Merck, Company Website, September 2023)
Small Molecule Drug Discovery Market Report Coverage and Deliverables
The "Small Molecule Drug Discovery Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:
- Small molecule drug discovery market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Small molecule drug discovery market trends, as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST and SWOT analysis
- Small molecule drug discovery market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the small molecule drug discovery market
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Therapeutic Area ; Process/Phase ; and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
The market is expected to register a CAGR of 9.7% during 2023–2031.
The small molecule drug discovery market value is expected to reach US$ 106.77 billion by 2031.
Bristol-Myers Squibb Co, Merck KGaA, GSK Plc, Boehringer Ingelheim International GmbH, Thermo Fisher Scientific Inc, ICON Plc, Danaher Corp, Charles River Laboratories International Inc, Oncodesign Services, and Revvity Inc are among the key players in the market.
The growing adoption of artificial intelligence in drug discovery is expected to be a prime trend in the market in the coming years.
The flourishing pharmaceutical industry with a surge in R&D activities and the growing inclination toward outsourcing are among the most significant factors fueling the market growth.
North America dominated the market in 2023.
1. Introduction 19
1.1 The Insight Partners Research Report Guidance. 19
1.2 Market Segmentation. 20
2. Executive Summary 21
2.1 Key Insights. 21
3. Research Methodology 22
3.1 Secondary Research. 23
3.2 Primary Research. 23
3.2.1 Hypothesis formulation: 23
3.2.2 Macro-economic factor analysis: 24
3.2.1 Developing base number: 24
3.2.2 Data Triangulation: 24
3.2.3 Country level data: 24
4. Small Molecule Drug Discovery Market Landscape 25
4.1 Overview. 25
4.2 PEST Analysis. 25
5. Small Molecule Drug Discovery Market – Key Market Dynamics 26
5.1 Small Molecule Drug Discovery Market – Key Market Dynamics. 26
5.2 Market Drivers. 26
5.2.1 Flourishing Pharmaceutical Industry with Surge in R&D Activities. 26
5.2.2 Growing Inclination Toward Outsourcing. 27
5.3 Market Restraints. 28
5.3.1 High Drug Development Cost 28
5.4 Market Opportunities. 28
5.4.1 Increasing Small Molecule-Based Pipeline. 28
5.5 Future Trends. 29
5.5.1 Growing Adoption of Artificial Intelligence in Drug Discovery. 29
5.6 Impact of Drivers and Restraints: 30
6. Small Molecule Drug Discovery Market – Global Market Analysis 31
6.1 Small Molecule Drug Discovery Market Revenue (US$ Million), 2021–2031. 31
6.2 Small Molecule Drug Discovery Market Forecast Analysis. 31
7. Small Molecule Drug Discovery Market Analysis – by Therapeutic Area 32
7.1 Oncology. 33
7.1.1 Overview. 33
7.1.2 Oncology: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 33
7.2 Central Nervous System.. 34
7.2.1 Overview. 34
7.2.2 Central Nervous System: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 35
7.3 Cardiovascular 36
7.3.1 Overview. 36
7.3.2 Cardiovascular: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 36
7.4 Respiratory. 37
7.4.1 Overview. 37
7.4.2 Respiratory: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 37
7.5 Orthopedics. 38
7.5.1 Overview. 38
7.5.2 Orthopedics: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 39
7.6 Immunology. 40
7.6.1 Overview. 40
7.6.2 Immunology: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 40
7.7 Rare Diseases. 41
7.7.1 Overview. 41
7.7.2 Rare Diseases: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 41
7.8 Other Therapeutic Areas. 42
7.8.1 Overview. 42
7.8.2 Other Therapeutic Areas: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 42
8. Small Molecule Drug Discovery Market Analysis – by Process or Phase 43
8.1 Target Discovery. 43
8.1.1 Overview. 43
8.1.2 Target Discovery: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 44
8.2 Target Validation. 45
8.2.1 Overview. 45
8.2.2 Target Validation: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 45
8.3 Lead Generation and Refinement 46
8.3.1 Overview. 46
8.3.2 Lead Generation and Refinement: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 46
8.4 Preclinical Development 47
8.4.1 Overview. 47
8.4.2 Preclinical Development: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 47
9. Small Molecule Drug Discovery Market – Geographical Analysis 49
9.1 North America. 49
9.1.1 North America Small Molecule Drug Discovery Market Overview. 49
9.1.2 North America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 49
9.1.3 North America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Therapeutic Area. 50
9.1.4 North America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Process or Phase. 50
9.1.5 North America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Country. 51
9.1.5.1 United States: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 51
9.1.5.1.1 United States: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 52
9.1.5.1.2 United States: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 53
9.1.5.2 Canada: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 53
9.1.5.2.1 Canada: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 54
9.1.5.2.2 Canada: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 55
9.1.5.3 Mexico: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 55
9.1.5.3.1 Mexico: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 56
9.1.5.3.2 Mexico: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 56
9.2 Europe. 58
9.2.1 Europe Small Molecule Drug Discovery Market Overview. 58
9.2.2 Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 58
9.2.3 Europe: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Therapeutic Area. 59
9.2.4 Europe: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Process or Phase. 59
9.2.5 Europe: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Country. 60
9.2.5.1 Germany: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 60
9.2.5.1.1 Germany: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 61
9.2.5.1.2 Germany: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 61
9.2.5.2 France: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 62
9.2.5.2.1 France: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 63
9.2.5.2.2 France: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 63
9.2.5.3 United Kingdom: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 64
9.2.5.3.1 United Kingdom: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 65
9.2.5.3.2 United Kingdom: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 65
9.2.5.4 Italy: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 66
9.2.5.4.1 Italy: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 67
9.2.5.4.2 Italy: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 67
9.2.5.5 Spain: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 68
9.2.5.5.1 Spain: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 69
9.2.5.5.2 Spain: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 69
9.2.5.6 Rest of Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 70
9.2.5.6.1 Rest of Europe: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 70
9.2.5.6.2 Rest of Europe: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 71
9.3 Asia Pacific. 72
9.3.1 Asia Pacific Small Molecule Drug Discovery Market Overview. 72
9.3.2 Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 72
9.3.3 Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Therapeutic Area. 73
9.3.4 Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Process or Phase. 73
9.3.5 Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Country. 74
9.3.5.1 Japan: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 74
9.3.5.1.1 Japan: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 75
9.3.5.1.2 Japan: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 76
9.3.5.2 China: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 76
9.3.5.2.1 China: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 77
9.3.5.2.2 China: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 78
9.3.5.3 India: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 78
9.3.5.3.1 India: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 79
9.3.5.3.2 India: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 80
9.3.5.4 South Korea: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 80
9.3.5.4.1 South Korea: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 81
9.3.5.4.2 South Korea: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 81
9.3.5.5 Australia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 82
9.3.5.5.1 Australia: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 83
9.3.5.5.2 Australia: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 83
9.3.5.6 Rest of APAC: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 84
9.3.5.6.1 Rest of APAC: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 85
9.3.5.6.2 Rest of APAC: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 85
9.4 Middle East & Africa. 86
9.4.1 Middle East & Africa Small Molecule Drug Discovery Market Overview. 86
9.4.2 Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 86
9.4.3 Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Therapeutic Area. 87
9.4.4 Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Process or Phase. 87
9.4.5 Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Country. 88
9.4.5.1 Saudi Arabia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 88
9.4.5.1.1 Saudi Arabia: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 89
9.4.5.1.2 Saudi Arabia: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 90
9.4.5.2 United Arab Emirates: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 90
9.4.5.2.1 United Arab Emirates: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 91
9.4.5.2.2 United Arab Emirates: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 92
9.4.5.3 South Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 92
9.4.5.3.1 South Africa: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 93
9.4.5.3.2 South Africa: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 94
9.4.5.4 Rest of Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 94
9.4.5.4.1 Rest of Middle East & Africa: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 95
9.4.5.4.2 Rest of Middle East & Africa: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 96
9.5 South & Central America. 97
9.5.1 South & Central America Small Molecule Drug Discovery Market Overview. 97
9.5.2 South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 97
9.5.3 South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Therapeutic Area. 98
9.5.4 South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Process or Phase. 98
9.5.5 South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast Analysis – by Country. 99
9.5.5.1 Brazil: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 99
9.5.5.1.1 Brazil: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 100
9.5.5.1.2 Brazil: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 100
9.5.5.2 Argentina: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 101
9.5.5.2.1 Argentina: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 102
9.5.5.2.2 Argentina: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 102
9.5.5.3 Rest of South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 103
9.5.5.3.1 Rest of South & Central America: Small Molecule Drug Discovery Market Breakdown, by Therapeutic Area. 104
9.5.5.3.2 Rest of South & Central America: Small Molecule Drug Discovery Market Breakdown, by Process or Phase. 104
10. Industry Landscape 105
10.1 Overview. 105
11. Company Profiles 106
11.1 Bristol-Myers Squibb Co. 106
11.1.1 Key Facts. 106
11.1.2 Business Description. 106
11.1.3 Products and Services. 106
11.1.4 Financial Overview. 107
11.1.5 SWOT Analysis. 108
11.1.6 Key Developments. 108
11.2 Merck KGaA. 109
11.2.1 Key Facts. 109
11.2.2 Business Description. 109
11.2.3 Products and Services. 109
11.2.4 Financial Overview. 110
11.2.5 SWOT Analysis. 111
11.2.6 Key Developments. 111
11.3 GSK Plc. 112
11.3.1 Key Facts. 112
11.3.2 Business Description. 112
11.3.3 Products and Services. 112
11.3.4 Financial Overview. 113
11.3.5 SWOT Analysis. 114
11.3.6 Key Developments. 115
11.4 Thermo Fisher Scientific Inc. 116
11.4.1 Key Facts. 116
11.4.2 Business Description. 116
11.4.3 Products and Services. 116
11.4.4 Financial Overview. 117
11.4.5 SWOT Analysis. 118
11.4.6 Key Developments. 119
11.5 ICON Plc. 120
11.5.1 Key Facts. 120
11.5.2 Business Description. 120
11.5.3 Products and Services. 120
11.5.4 Financial Overview. 121
11.5.5 SWOT Analysis. 122
11.5.6 Key Developments. 122
11.6 Danaher Corp. 123
11.6.1 Key Facts. 123
11.6.2 Business Description. 123
11.6.3 Products and Services. 123
11.6.4 Financial Overview. 124
11.6.5 SWOT Analysis. 125
11.6.6 Key Developments. 125
11.7 Charles River Laboratories InternationalInc. 126
11.7.1 Key Facts. 126
11.7.2 Business Description. 126
11.7.3 Products and Services. 126
11.7.4 Financial Overview. 127
11.7.5 SWOT Analysis. 128
11.7.6 Key Developments. 129
11.8 Oncodesign Services. 130
11.8.1 Key Facts. 130
11.8.2 Business Description. 130
11.8.3 Products and Services. 130
11.8.4 Financial Overview. 130
11.8.5 SWOT Analysis. 131
11.8.6 Key Developments. 131
11.9 Revvity Inc. 132
11.9.1 Key Facts. 132
11.9.2 Business Description. 132
11.9.3 Products and Services. 132
11.9.4 Financial Overview. 132
11.9.5 SWOT Analysis. 134
11.9.6 Key Developments. 134
11.10 Boehringer Ingelheim International GmbH. 135
11.10.1 Key Facts. 135
11.10.2 Business Description. 135
11.10.3 Products and Services. 135
11.10.4 Financial Overview. 136
11.10.5 SWOT Analysis. 137
11.10.6 Key Developments. 137
12. Appendix 138
12.1 About The Insight Partners. 138
12.2 Glossary of Terms. 139
List of Tables
Table 1. Small Molecule Drug Discovery Market Segmentation. 20
Table 2. R&D Investments by Major Pharmaceutical Companies. 27
Table 3. Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 31
Table 4. North America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 50
Table 5. North America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 50
Table 6. United States: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 52
Table 7. United States: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 53
Table 8. Canada: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 54
Table 9. Canada: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 55
Table 10. Mexico: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 56
Table 11. Mexico: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 56
Table 12. Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 59
Table 13. Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 59
Table 14. Germany: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 61
Table 15. Germany: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 61
Table 16. France: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 63
Table 17. France: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 63
Table 18. United Kingdom: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 65
Table 19. United Kingdom: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 65
Table 20. Italy: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 67
Table 21. Italy: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 67
Table 22. Spain: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 69
Table 23. Spain: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 69
Table 24. Rest of Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 70
Table 25. Rest of Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 71
Table 26. Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 73
Table 27. Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 73
Table 28. Japan: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 75
Table 29. Japan: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 76
Table 30. China: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 77
Table 31. China: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 78
Table 32. India: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 79
Table 33. India: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 80
Table 34. South Korea: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 81
Table 35. South Korea: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 81
Table 36. Australia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 83
Table 37. Australia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 83
Table 38. Rest of APAC: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 85
Table 39. Rest of APAC: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 85
Table 40. Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 87
Table 41. Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 87
Table 42. Saudi Arabia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 89
Table 43. Saudi Arabia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 90
Table 44. United Arab Emirates: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 91
Table 45. United Arab Emirates: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 92
Table 46. South Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 93
Table 47. South Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 94
Table 48. Rest of Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) – by Therapeutic Area. 95
Table 49. Rest of Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 96
Table 50. South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 98
Table 51. South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 98
Table 52. Brazil: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 100
Table 53. Brazil: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 100
Table 54. Argentina: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 102
Table 55. Argentina: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Process or Phase. 102
Table 56. Rest of South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) – by Therapeutic Area. 104
Table 57. Rest of South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) – by Process or Phase. 104
Table 58. Recent Inorganic Growth Strategies in the Small Molecule Drug Discovery Market 105
Table 59. Glossary of Terms, Small Molecule Drug Discovery Market 139
List of Figures
Figure 1. Small Molecule Drug Discovery Market Segmentation, by Geography. 20
Figure 2. PEST Analysis. 25
Figure 3. Impact Analysis of Drivers and Restraints. 30
Figure 4. Small Molecule Drug Discovery Market Revenue (US$ Million), 2021–2031. 31
Figure 5. Small Molecule Drug Discovery Market Share (%) – by Therapeutic Area (2023 and 2031) 32
Figure 6. Oncology: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 33
Figure 7. Central Nervous System: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 35
Figure 8. Cardiovascular: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 36
Figure 9. Respiratory: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 37
Figure 10. Orthopedics: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 39
Figure 11. Immunology: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 40
Figure 12. Rare Diseases: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 41
Figure 13. Other Therapeutic Areas: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 42
Figure 14. Small Molecule Drug Discovery Market Share (%) – by Process or Phase (2023 and 2031) 43
Figure 15. Target Discovery: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 44
Figure 16. Target Validation: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 45
Figure 17. Lead Generation and Refinement: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 46
Figure 18. Preclinical Development: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 47
Figure 19. North America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 49
Figure 20. North America: Small Molecule Drug Discovery Market Breakdown, by Key Countries, 2023 and 2031 (%) 51
Figure 21. United States: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 51
Figure 22. Canada: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 53
Figure 23. Mexico: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 55
Figure 24. Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 58
Figure 25. Europe: Small Molecule Drug Discovery Market Breakdown, by Key Countries, 2023 and 2031 (%) 60
Figure 26. Germany: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 60
Figure 27. France: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 62
Figure 28. United Kingdom: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 64
Figure 29. Italy: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 66
Figure 30. Spain: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 68
Figure 31. Rest of Europe: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 70
Figure 32. Asia Pacific: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 72
Figure 33. Asia Pacific: Small Molecule Drug Discovery Market Breakdown, by Key Countries, 2023 and 2031 (%) 74
Figure 34. Japan: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 74
Figure 35. China: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 76
Figure 36. India: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 78
Figure 37. South Korea: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 80
Figure 38. Australia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 82
Figure 39. Rest of APAC: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 84
Figure 40. Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 86
Figure 41. Middle East & Africa: Small Molecule Drug Discovery Market Breakdown, by Key Countries, 2023 and 2031 (%) 88
Figure 42. Saudi Arabia: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 88
Figure 43. United Arab Emirates: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 90
Figure 44. South Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 92
Figure 45. Rest of Middle East & Africa: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 94
Figure 46. South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 97
Figure 47. South & Central America: Small Molecule Drug Discovery Market Breakdown, by Key Countries, 2023 and 2031 (%) 99
Figure 48. Brazil: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 99
Figure 49. Argentina: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031(US$ Million) 101
Figure 50. Rest of South & Central America: Small Molecule Drug Discovery Market – Revenue and Forecast to 2031 (US$ Million) 103
The List of Companies - Small Molecule Drug Discovery Market
- Bristol-Myers Squibb Co
- Merck KGaA
- GSK Plc
- Boehringer Ingelheim International GmbH
- Thermo Fisher Scientific Inc
- ICON Plc
- Danaher Corp
- Charles River Laboratories International Inc
- Oncodesign Services
- Revvity Inc
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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