血脑屏障技术市场规模预计将从 2021 年的 10.4105 亿美元增至 2028 年的 51.0194 亿美元;预计 2021 年至 2028 年的复合年增长率为 25.5%。
大脑被一种称为脑脊液的保护性液体和一种称为脑膜的保护膜包围。血脑屏障是大脑血管与构成脑组织的细胞和其他成分之间的另一种保护元素。血脑屏障保护大脑免受血液中可能存在的致病病原体/毒素的侵害。它阻止外来物质进入脑组织。它还阻止用于治疗神经退行性疾病和神经炎症事件的救命药物通过。因此,用于通过血脑屏障输送药物的技术与用于将药物输送到其他身体部位的技术不同。
血脑屏障技术市场根据技术、应用和地域进行细分。按地域划分,市场进一步细分为北美、欧洲、亚太地区、中东和非洲以及南美和中美。该报告提供了对市场的见解和深入分析,强调了市场趋势、技术进步和市场动态等参数,以及对全球领先市场参与者的竞争格局的分析。
定制研究以满足您的需求
我们可以优化和定制标准产品无法满足的分析和范围。这种灵活性将帮助您获得业务规划和决策所需的准确信息。
血脑屏障技术市场:
复合年增长率(2021 - 2028 年)25.5%- 2021 年市场规模
10.4 亿美元 - 2028 年市场规模
51 亿美元
市场动态
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
关键人物;主力;重要一员
- 梯瓦制药工业有限公司
- F.霍夫曼-罗氏有限公司
- 礼来公司
- 百时美施贵宝公司
- 辉瑞公司
- 强生服务公司
- Fabre-Kramer 制药公司
- Bioasis 技术公司
- 阿布利瓦公司
区域概况
- 北美
- 欧洲
- 亚太
- 南美洲和中美洲
- 中东和非洲
市场细分
- 双特异性抗体 RMT 方法
- 特洛伊木马方法
- 提高渗透率
- 被动扩散
- 其他非侵入性 BBB 技术
- 阿尔茨海默氏病
- 癫痫
- 帕金森氏症
- 多发性硬化症
- 亨特氏综合症
- 脑癌
- 其他的
- 北美
- 欧洲
- 亚太地区
- 中东和非洲
- 南美洲和中美洲
- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
市场洞察
神经系统疾病患病率不断上升推动血脑屏障技术市场增长
癫痫和癫痫发作、帕金森病、痴呆、自闭症、阿尔茨海默病、脑瘤和脑瘫等神经系统疾病会影响人体的大脑和神经。在美国,神经系统疾病的患病率正在上升。根据美国疾病控制和预防中心 (CDC) 的数据,阿尔茨海默病是美国十大死亡原因之一。2020 年,阿尔茨海默病影响了美国 580 万人。同样,根据帕金森病基金会患病率项目的估计,美国在 2020 年记录了 930,000 例帕金森病病例。此外,根据阿尔茨海默病协会的估计,超过 600 万美国人患有阿尔茨海默病,预计到 2050 年这一数字将达到约 1300 万。此外,自 COVID-19 大流行以来,美国因阿尔茨海默病和痴呆症死亡的人数增加了 16%。另一方面,2000-2019 年间,因阿尔茨海默病死亡的人数增加了 145%。
癫痫是一种非传染性慢性脑部疾病,影响所有年龄段的人。根据世界卫生组织 (WHO) 称,全世界约有 5000 万人患有癫痫,癫痫是世界上最常见的神经系统疾病之一。约 80% 的癫痫患者生活在中低收入国家。同一消息来源估计,如果接受正确的诊断和治疗,多达 70% 的癫痫患者可以摆脱癫痫发作。痴呆症目前是所有疾病中第七大致死原因,也是全球老年人残疾和成瘾的主要原因之一。据世界卫生组织称,全世界有超过 5500 万人患有痴呆症,每年新增约 1000 万例痴呆症病例。这种疾病是由多种主要或次要影响大脑的疾病和损伤引起的。阿尔茨海默病是最常见的痴呆症,可能导致 60-70% 的病例。因此,神经系统疾病的日益流行需要先进的血脑屏障技术进行治疗,这正在推动市场增长。
老年人口的增加和与年龄相关的神经系统疾病患病率的上升促进了血脑屏障技术市场的增长
一些神经系统疾病,如中风、神经病、阿尔茨海默病和帕金森病在老年人中更为常见,随着预期寿命的提高,这些疾病的患病率也在上升。根据世界卫生组织的数据,全球人口正在迅速老龄化。2015-2050年期间,全球60岁以上人口将几乎翻一番,其比例将从12%增至22%。老年人的精神和神经系统疾病可能占该年龄组总伤残调整生命年(DALY)的6.6%。此外,根据同一来源,约15%的60岁以上成年人患有精神疾病。
据美国疾病控制与预防中心称,阿尔茨海默病是 65 岁以上人群第五大死亡原因。此外,阿尔茨海默病患者数量每五年翻一番。2020 年,阿尔茨海默病影响了约 580 万属于该年龄段的美国人,到 2060 年,这一数字预计将增长近三倍,达到 1400 万。神经系统疾病导致的死亡率也在上升。据阿尔茨海默病协会称,美国每年有三分之一的老年人死于阿尔茨海默病或痴呆症。
因此,与年龄相关的神经系统疾病患病率的上升推动了对血脑屏障技术的需求,以实现更好的药物输送。
技术洞察
根据技术,全球血脑屏障技术市场细分为双特异性抗体 RMT 方法、特洛伊木马方法、增加渗透性、被动扩散和其他非侵入性 BBB 技术。2020 年,增加渗透性细分市场占据了最大的市场份额。然而,试剂细分市场预计将在 2021-2028 年期间实现市场上最高的复合年增长率。血脑屏障 (BBB) 渗透性的增加与内皮间连接复合体的重塑和脑内皮细胞之间的间隙形成 (旁细胞途径) 以及脑内皮细胞顶端和基底侧之间的密集胞饮囊泡运输 (跨细胞途径) 有关。增加渗透性细分市场市场的增长可以归因于对治疗许多神经和中枢神经系统疾病的研究活动的日益关注。
应用程序洞察
根据应用,血脑屏障技术市场细分为阿尔茨海默病、癫痫、帕金森病、多发性硬化症、亨特氏综合征、脑癌等。帕金森病领域预计将在 2021 年占据最大的市场份额。
产品发布和并购是全球血脑屏障技术市场参与者广泛采用的策略。以下列出了一些近期的关键市场发展:
2021 年 12 月,礼来公司收购了生物技术公司 Prevail Therapeutics。交易完成后,礼来公司计划为患有帕金森症等神经退行性疾病的人创建基因治疗项目。
2020年10月,百时美施贵宝宣布加拿大卫生部批准ZEPOSIA(ozanimod)用于治疗复发缓解型多发性硬化症(RRMS)患者,以减少临床发作的频率。
根据四位伦敦帝国理工学院学者的初步研究(尚未经过同行评审)以及其他基于研究的证据,COVID-19 感染可能会导致神经系统问题。这一观点是在大流行的第一波期间发展起来的。血脑屏障是内皮细胞的半透膜,可将大脑与身体其他部分的成分和机制隔离开来。单核细胞是一种白细胞,当 SARS-CoV-2 进入血液时,它会作为人体防御机制的一部分被激活。为了让单核细胞穿过血脑屏障,需要激活一种复杂的机制。根据同一项研究,“血脑屏障有助于受感染和激活的单核细胞进入中枢神经系统,从而使 SARS-CoV-2 病毒穿过松弛的血脑屏障。因此,对用于检测 COVID-19 患者神经系统问题的血脑屏障技术的需求不断增长,对市场增长产生了积极影响。
血脑屏障技术——市场细分
全球血脑屏障技术市场细分为技术、应用和地域。在技术方面,市场细分为双特异性抗体 RMT 方法、特洛伊木马方法、增加渗透性、被动扩散和其他非侵入性 BBB 技术。根据应用,血脑屏障技术市场细分为阿尔茨海默病、癫痫、帕金森病、多发性硬化症、亨特氏综合征、脑癌等。
血脑屏障技术市场报告范围
报告属性 | 细节 |
---|---|
2021 年市场规模 | 10.4亿美元 |
2028 年市场规模 | 51亿美元 |
全球复合年增长率(2021 - 2028) | 25.5% |
历史数据 | 2019-2020 |
预测期 | 2022-2028 |
涵盖的领域 | 按技术分类
|
覆盖地区和国家 | 北美
|
市场领导者和主要公司简介 |
|
- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
公司简介
- 梯瓦制药工业有限公司
- F.霍夫曼-罗氏有限公司
- 礼来公司。
- 百时美施贵宝公司
- 辉瑞公司
- 强生服务公司
- Fabre-Kramer 制药公司
- Bioasis 技术公司
- 阿布利瓦公司
- JCR制药有限公司
- Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
- PEST and SWOT Analysis
- Market Size Value / Volume - Global, Regional, Country
- Industry and Competitive Landscape
- Excel Dataset
- Automotive Fabric Market
- Transdermal Drug Delivery System Market
- Online Recruitment Market
- Joint Pain Injection Market
- Energy Recovery Ventilator Market
- GMP Cytokines Market
- Industrial Inkjet Printers Market
- Non-Emergency Medical Transportation Market
- Unit Heater Market
- Aesthetic Medical Devices Market
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
Nanoparticles for brain drug delivery is likely to act as trend the market growth in the comping years.
Increasing permeability is the most influencing segment growing in the blood brain barrier technologies market.
Large number of product approvals and launches are likely to fuel the market growth in the comping years.
Key players in the market are Teva Pharmaceutical Industries Ltd., F. Hoffmann-La Roche Ltd., Eli Lilly and Company., Bristol-Myers Squibb Company, Pfizer, Inc., Johnson and Johnson Services, Inc., Fabre-Kramer Pharmaceuticals, Inc., Bioasis Technologies Inc., Abliva AB, and JCR Pharmaceuticals Co., Ltd. among others.
Key factors driving the growth of the market are growing prevalence of neurological disorders and increasing geriatric population and neurological disorders associated with age are among the key factors driving the market.
The brain is surrounded by protective fluid known as cerebrospinal fluid and a protective membrane called the meninges. Similar another protective element is the blood brain barrier. this is a barrier between the brain's blood vessels and the cells and other components that together make up brain tissue. The blood brain barrier protects against disease-causing pathogens/toxins that may be present in the blood. It blocks the passage of foreign substances entering the brain tissue. It also blocks the passage of life-saving drugs used to treat neurodegeneration and neuroinflammation events. Thus, different technologies are used to deliver drugs across blood brain barrier.
Asia-Pacific is the lucrative for the blood brain barrier technologies market.
Trends and growth analysis reports related to Life Sciences : READ MORE..
The List of Companies - Blood Brain Barrier Technologies Market
- Teva Pharmaceutical Industries Ltd.
- F. Hoffmann-La Roche Ltd.
- Eli Lilly and Company
- Bristol-Myers Squibb Company
- Pfizer, Inc.
- Johnson and Johnson Services, Inc.
- Fabre-Kramer Pharmaceuticals, Inc.
- Bioasis Technologies Inc.
- Abliva AB
- JCR Pharmaceuticals Co., Ltd.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.