CRISPR and Cas Gene Market Forecast to 2030 - Size & Share
市场洞察和分析师观点：
该报告包括由于当前 CRISPR 和 Cas 基因市场趋势及其在预测期间的可预见影响而产生的增长前景时期。癌症和遗传疾病患病率不断上升，以及越来越多地采用基于 CRISPR 的筛选和改进的基因组目标等因素推动了市场的增长。然而，与 CRISPR 技术相关的脱靶效应和伦理问题阻碍了市场的增长。未来几年，基因组研究经费的增加以及为证明 CRISPR 在基因组学中的有效性所做的努力可能会给市场带来新的趋势。
CRISPR 技术可用于识别许多肿瘤的突变。它们识别人类肿瘤特有的修饰蛋白。因此，CRISPR技术对癌症等慢性病的个性化治疗推动了市场的扩张。此外，生物技术公司对新疗法的投资等因素；加强基因组研究和开发；癌症、血源性疾病等负担的增加正在促进CRISPR和Cas基因市场的增长。然而，CRISPR 在药物开发和治疗过程中的使用因其脱靶的可能性而受到限制，从而限制了市场的进步。
增长动力：
癌症和遗传性疾病患病率的增加推动市场增长
据美国癌症协会估计，到 2022 年，美国被诊断患有癌症的人数预计为 190 万人。此外，《自然》杂志 2022 年 11 月发表的一篇论文指出，研究人员可以使用 CRISPR 基因编辑来改变免疫细胞识别癌症。改变了人体肿瘤特有的蛋白质。然后，这些细胞可以安全地输送到体内，以找到消除的目标，从而有助于针对癌症和其他慢性疾病的个性化治疗选择。
遗传性疾病的患病率日益增加，进一步推动了对基因编辑技术的需求，例如CRISPR 和 Cas 基因。据世界卫生组织 (WHO) 称，全世界有数百万人受到遗传性疾病的影响，几乎每 20 名活产婴儿中就有 1 人患有遗传性疾病。 CRISPR/Cas系统可用作开发各种遗传疾病治疗方法的潜在工具，包括镰状细胞性贫血、囊性纤维化和亨廷顿病。许多临床试验正在进行中，以测试基于 CRISPR 的遗传性疾病疗法的安全性和有效性。因此，在治疗癌症和其他慢性遗传疾病的各个治疗领域对 CRISPR 和 Cas 基因技术的需求不断增长，推动了 CRISPR 和 Cas 基因市场的增长。
报告细分和范围：
CRISPR 和 Cas 基因市场分析是通过考虑以下细分市场进行的：产品和服务、应用程序和最终用户。
细分分析：
根据应用，CRISPR 和 Cas 基因市场分为生物医学和农业。生物医学领域到 2022 年将占据更大的市场份额。预计该领域在预测期内的复合年增长率将达到 23.8%。 CRISPR基因编辑技术正在应用于生命科学的不同领域。完善的递送方法和纳米载体的使用进一步提高了该技术的有效性和特异性。已经进行了各种研究来解释使用这种方法来修饰人类体细胞和多能干细胞基因组。一些公司还提供商业试剂盒和服务，通过使用 CRISPR 基因编辑技术来协助研究人员。
通过创新育种技术改善农业生产，让全世界能够更好地获取营养丰富的食品。 2019年6月，冷泉港实验室的研究人员实施了CRISPR/Cas9技术，用于诱导番茄开花抑制基因突变，从而导致番茄快速开花并改善紧凑生长，最终实现提早增产。
CRISPR和Cas基因按产品和服务划分的市场 – 2022 年和 2030 年
CRISPR 和 Cas 基因市场按产品和服务划分，分为产品和服务。该产品细分市场将在 2022 年占据更大的市场份额。预计该细分市场在预测期内的复合年增长率将达到 23.9%。为了满足不断增长的需求，已经开发和引进了许多尖端技术，例如CRISPR和Cas基因编辑试剂盒。这些试剂盒在整个市场中份额的激增归因于改进的单一产品的可用性，这些产品可以实现不同的目标，包括简单的基因敲除、减少脱靶切割、选择性基因组切割、基因组工程和更高的特异性。在预测期内，增加与基因编辑相关的研发投资将进一步有利于整个 CRISPR 和 Cas Gene 市场。
按最终用户划分，市场分为生物技术和制药公司、学术界和政府研究机构，以及合同研究组织 (CRO) 和 CDMO。到2022年，生物技术和制药公司领域占据了最大的CRISPR和Cas基因市场份额。预计在预测期内复合年增长率最高为24.2%。生物技术和制药公司利用这些技术快速识别和验证新的治疗靶点，并在更短的时间内创建更好的人类疾病生物模型。他们还将基因修饰技术用于商业目的。
区域分析：
CRISPR 和 Cas 基因市场报告的范围涉及北美、欧洲、亚太地区、南美洲和中美洲以及中东和非洲。 2022年，北美拥有最大的CRISPR和Cas基因市场份额。该地区的市场增长是由生物制药行业蓬勃发展的研发业务以及多家制药公司参与新型疗法的开发推动的。 2020年5月，默克获得美国食品和药物管理局（FDA）批准两项CRISPR Cas9驱动的基因编辑专利。此外，美国和加拿大的各种联邦举措支持农业生物技术研究和基于 CRISPR 的植物产品的商业发布。许多制药和种子公司已投资于合作、收购和合作等增长战略，分别推动制药市场和作物生长，这将进一步提振这些行业对 CRISPR 技术的需求。
欧洲预计将占据主导地位全球CRISPR和Cas基因市场份额第二大。欧洲当局对基因治疗和转基因生物等新技术实行了更严格的监管。尽管有严格的监管，该地区仍在生物医学、医疗、农业和治疗应用中迅速采用 CRISPR 技术。
预计亚太地区在预测期内将实现市场上最快的复合年增长率 24.3%。该地区的市场增长归因于政府增加对研发的投资以开发新的治疗方法。中国的公司和研究机构正在开展用于药物开发的基因组编辑研究，最近宣布了几项临床试验，以寻求批准将 CRISPR 用于癌症治疗。 2021年3月，日本生物技术公司Setsuro Tech获得了总部位于都柏林的ERS Genomics开发的CRISPR-Cas9技术的专利。此类举措预计将推动未来 CRISPR 技术在亚太地区的采用。
行业发展和未来机遇：
CRISPR 和 Cas 基因市场预测可以帮助该市场的利益相关者规划其增长战略。下面列出了领先市场参与者的一些战略发展：
2023 年 2 月，Ensoma 收购了 Twelve Bio ApS，以进一步开发其体内工程细胞药物组合。 Twelve Bio 是一家致力于探索下一代 CRISPR-Cas 药物治疗应用的公司。 2022 年 12 月，加州大学的一名研究人员开始了一项名为“Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified”的临床试验严重镰状细胞病患者的造血祖干细胞 (CRISPR_SCD001)”，以评估使用 CRISPR/Cas9 编辑的红细胞（称为 CRISPR_SCD001 药品）的造血干细胞移植 (HSCT)。 2022 年 11 月，研究人员麻省理工学院开发了一种基于 CRISPR 的 PASTE 工具，可将大 DNA 序列插入所需的细胞位置。该技术可潜在用于治疗各种遗传疾病。 2021 年 11 月，加拿大卫生部批准了 CRISPR Therapeutics 和 ViaCyte 提交的 VCTX210 临床试验申请，这是一种用于治疗 1 型糖尿病的 CRISPR 工程干细胞疗法。竞争格局和主要公司：
CRISPR Therapeutics；赛默飞世尔科技；默克；金斯瑞；凯杰；宝生物公司；大脑生物技术股份公司； Intellia 治疗公司；新英格兰生物实验室；和 Editas Medicine, Inc. 是 CRISPR 和 Cas 基因市场报告中介绍的知名公司之一。这些公司专注于开发新技术、升级现有产品并扩大其地域分布，以满足全球不断增长的消费者需求。
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
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North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
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Frequently Asked Questions
The factors driving the growth of the CRISPR and Cas gene market include the increasing prevalence of cancer and genetic diseases, and the burgeoning adoption of CRISPR-based screens with improved genomic targets.
The CRISPR technology is useful in identifying mutations in many tumors. They recognize modified proteins that are specific to human tumors. The technology can safely be utilized to find their targets for elimination. Therefore, personalized treatments enabled by CRISPR technology for chronic diseases such as cancer drive the CRISPR and Cas gene market growth. In addition, factors such as investments by biotech companies in new treatments; increased genomic research and development; and the rising burden of cancer, bloodborne diseases, and so on are facilitating the expansion of the market.
The CRISPR and Cas gene market is expected to be valued at US$ 15.10 billion in 2030.
The CRISPR and Cas gene market majorly consists of the players such as CRISPR Therapeutics; Thermo Fisher Scientific; Merck; GenScript; Qiagen; Takara Bio Inc.; Brain Biotech AG; Intellia Therapeutics, Inc.; New England Biolabs; and Editas Medicine, Inc.
The CRISPR and Cas gene market was valued at US$ 2.78 billion in 2022.
The global CRISPR and Cas gene market, based on product & service is segmented into products and services. The products segment held a larger market share in 2022. The same segment is expected to register a higher CAGR of 23.9% during the forecast period. Based on application, the CRISPR and Cas gene market is segmented into biomedical and agriculture. The biomedical segment held a larger market share in 2022. The same segment is anticipated to register a higher CAGR of 23.8% during 2022–2030. In terms of end user, the CRISPR and Cas gene market is segmented into biotechnology and pharmaceutical companies, academics and government research institutes, and contract research organizations (CROs) and CDMOs. The biotechnology and pharmaceutical companies segment held the largest CRISPR and Cas gene market share in 2022. It is anticipated to register the highest CAGR of 24.2% during the forecast period.
The List of Companies - CRISPR and Cas Gene Market
- CRISPR Therapeutics
- BRAIN Biotech AG
- Thermo Fisher Scientific
- Merck KGaA
- Editas Medicine
- Takara Bio
- Genscript
- Qiagen
- New England Biolabs
- Intellia Therapeutics
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