Dental Bone Graft Substitutes and Barrier Membrane Market Report to 2030
[研究报告] 2022年牙科骨移植替代品和屏障膜市场价值为7.2204亿美元,预计到2030年将达到13.7992亿美元;预计2022年至2030年的复合年增长率为8.4%。
市场洞察和分析师观点:
牙科膜用于引导组织再生 (GTR) 和引导骨再生 (GBR)。市面上有各种牙科膜,创新膜也得到了广泛开发。牙科屏障膜通常需要提供屏障功能、生物安全性、生物相容性和适当的机械性能。此外,膜应该具有生物活性,促进组织再生。另一方面,牙科骨移植替代品是一种天然或合成材料,通常只含有矿化骨基质而不含活细胞。在不久的将来,具有安全性和标准化质量的异体骨替代品可能成为自体骨的首选;它们可以提供新的骨传导和骨诱导产品,具有更易于处理的形式和足够的吸收率,可与生长因子和/或细胞移植一起使用。根据每种临床情况,必须仔细选择异体骨移植产品才能获得良好的结果。牙科骨移植材料通常与生长因子和/或屏障膜一起使用,用于牙周再生疗法和植入前引导骨再生程序等情况。近年来,这些材料也被应用于治疗种植体周围炎引起的骨缺损。
增长动力和挑战:
据《英国牙科杂志》报道,大约 10% 到 12% 的炎症性上颌窦疾病是由牙齿引起的。这些疾病大多不仅与牙髓坏死和根尖周病有关,还与晚期牙周病以及牙槽手术后的口腔上颌窦交通有关。挤压出的牙髓腔填充材料在进入上颌窦时会起到局部刺激物的作用,并且容易引起曲霉病等真菌感染。近几十年来,人们一直在研究自体骨和各种骨替代物作为上颌窦底提升术的移植材料。最近,凝胶形式的异种和异体骨替代物已被提议作为经牙顶上颌窦底提升术的移植材料。这些生物材料由悬浮在水溶液中并嵌入胶原基质中的微粒(通常最大 300 μm)组成。这些生物材料通过鼻窦底部皮质进入鼻窦腔后,很容易注射到鼻窦下腔中。微粒化颗粒光滑,没有锋利或切割边缘,这是移植过程中鼻窦膜撕裂的风险因素。此外,由于凝胶状骨替代物具有糊状稠度和极小的尺寸,因此意外分散到鼻窦腔中的凝胶状骨替代物更容易通过纤毛活动通过 OMC 清除。这些因素促进了全球牙科骨移植替代品和屏障膜市场的增长,预计在预测期内将继续呈现类似的趋势。牙周病的范围从简单的牙龈炎到严重疾病,这些疾病会对支撑牙齿的软组织和骨骼造成严重损害;在最坏的情况下,牙齿会脱落。牙周病是美国的一个主要公共卫生问题,目前美国许多成年人都患有某种形式的牙周病。美国癌症研究协会(AACR)旗下期刊《癌症流行病学、生物标志物与预防》刊登的一项研究显示,牙周病与绝经后女性罹患多种癌症的风险增加有关。多学科数字出版研究所(MDPI)发表的《牙周病与口腔癌之间的联系——确定还是永无止境的困境》一文显示,美国超过50%的人口(包括18岁的成年人)患有牙周炎,35岁以上的人口中75%患有某种形式的牙周炎。牙周炎的严重程度也各不相同。根据不同的研究,这些疾病中有30–50%是轻微的,5–15%是严重的和全身性的。
在美国,一项全国性健康访谈调查显示,根据口腔健康评估,牙周炎的患病率很高;30 岁以上成年人的牙周炎患病率估计约为 47%,65 岁以上的人群则高达 70%。中度和重度牙周炎与全身炎症和免疫反应的关系更为密切,65 岁以上的成年人中中度和重度牙周炎的患病率明显较高。
癌症是美国主要公共卫生问题之一,也是美国第二大死亡原因。据美国卫生与公众服务部统计,口腔癌占美国每年确诊癌症病例的~3%,每年约有4.8万人被诊断患有口腔癌,约有9600人死于口腔癌。据美国疾病控制与预防中心统计,2020年美国每年确诊的癌症病例中,口腔和咽喉癌占3%。口腔癌的危险因素包括吸烟、过量饮酒和HPV感染。牙周病可导致牙槽骨吸收和破坏、牙周附着丧失、牙齿松动脱落。因此,牙周病的治疗重在消除感染源、刺激因素,注重修复牙周组织缺损,恢复正常形态和功能。骨移植是通过移植材料(骨或骨替代物)来修复牙周缺损,以恢复牙槽骨的解剖形态和牙周组织的功能。因此,牙周病和口腔癌病例的增加促进了牙科骨移植替代物和屏障膜市场的增长。
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牙科骨移植替代品和屏障膜市场:
Dental Bone Graft Substitutes and Barrier Membrane Market: Strategic Insights
Dental Bone Graft Substitutes and Barrier Membrane Market
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CAGR (2022 - 2030)
8.4%
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Market Size 2022
US$ 722.04 Million
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Market Size 2030
US$ 1,379.92 Million
Market Dynamics
GROWTH DRIVERS
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FUTURE TRENDS
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OPPORTUNITIES
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Key Players
- Geistlich Pharma AG
- Medtronic Plc
- Dentsply Sirona Inc
- Matricel GmbH
- ZimVie Inc
- Regenity Biosciences Inc
- Neoss UK Ireland Ltd
- Institut Straumann AG
- CAMLOG Biotechnologies GmbH
Regional Overview
- 北美(美国、加拿大、墨西哥)
- 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
- 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
- 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
- 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
Market Segmentation
产品(牙科骨移植替代品(同种异体移植、异种移植、合成骨移植、自体移植、异种移植、脱矿骨基质(DBM-同种异体移植等)和牙科屏障膜(可吸收膜和不可吸收膜))
手术(引导骨再生手术
- GBR、引导组织再生手术
最终用户(医院、牙科诊所等)
地理(北美洲、欧洲、亚太地区、中东和非洲、南美洲和中美洲)
Dental Bone Graft Substitutes and Barrier Membrane Market: Strategic Insights
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CAGR (2022 - 2030)8.4% -
Market Size 2022
US$ 722.04 Million -
Market Size 2030
US$ 1,379.92 Million
Market Dynamics
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
- XXXXXXX
Key Players
- Geistlich Pharma AG
- Medtronic Plc
- Dentsply Sirona Inc
- Matricel GmbH
- ZimVie Inc
- Regenity Biosciences Inc
- Neoss UK Ireland Ltd
- Institut Straumann AG
- CAMLOG Biotechnologies GmbH
Regional Overview
- 北美(美国、加拿大、墨西哥)
- 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
- 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
- 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
- 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
Market Segmentation
- GBR、引导组织再生手术
复合年增长率(2022 - 2030 年)8.4%- 2022 年市场规模
7.2204 亿美元 - 2030年市场规模
13.7992亿美元
市场动态
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
- 財政部
关键人物;主力;重要一员
- 盖氏制药公司
- 美敦力公司
- 登士柏西诺德公司
- 母公司马特里塞尔有限公司
- ZimVie 公司
- Regenity Biosciences Inc.
- Neoss 英国及爱尔兰有限公司
- 施特劳曼研究所
- CAMLOG 生物技术有限公司
区域概况
- 北美
- 欧洲
- 亚太
- 南美洲和中美洲
- 中东和非洲
市场细分
- 牙科骨移植替代品
- 引导骨再生程序
- 医院
- 牙科诊所
- 其他的
- 北美
- 欧洲
- 亚太地区
- 中东和非洲
- 南美洲和中美洲
- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
报告细分和范围:
根据产品,全球牙科骨移植替代品和屏障膜市场分为牙科骨移植替代品和牙科屏障膜。牙科骨移植替代品分为同种异体移植、异种移植、合成骨移植、牙科骨移植替代品分为同种异体移植、异种移植、合成骨移植和其他。另一方面,牙科屏障膜分为可吸收膜和不可吸收膜。根据程序,牙科骨移植替代品和屏障膜市场分为引导骨再生程序 (GBR)、引导组织再生程序 (GTR)、上颌窦提升程序和牙槽嵴劈开程序、牙槽嵴保存 (ARP)、块移植程序、牙周再生程序、牙槽窝保存和其他。根据最终用户,牙科骨移植替代品和屏障膜市场分为医院、牙科诊所和其他。根据地域划分,牙科骨移植替代品和屏障膜市场细分为北美(美国、加拿大和墨西哥)、欧洲(英国、德国、法国、意大利、西班牙和欧洲其他地区)、亚太地区(中国、日本、印度、澳大利亚、韩国和亚太其他地区)、中东和非洲(阿联酋、沙特阿拉伯、南非和中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷和南美洲和中美洲其他地区)。
节段分析:
根据最终用户,全球牙科骨移植替代品和屏障膜市场细分为医院、牙科诊所和其他。2022 年,牙科诊所部分占据最大的市场份额,预计在预测期内将实现最高的复合年增长率。在美国,牙科诊所的渗透率高于医院。从人口统计学上看,这在新兴国家和发展中国家可能略有不同,但与世界各地的医院相比,牙科诊所的渗透率或份额更高。根据 Express Dentist 的数据,2021 年,美国有 159,246 名牙医获得全科执业许可,10,921 名牙医获得正畸和牙颌矫形许可。美国老年人口的增加和美容牙科手术数量的增加也促进了整体市场的增长,预计将在预测期内继续催化整个牙科骨移植替代品和屏障膜市场。
区域分析:
北美是牙科骨移植替代品和屏障膜市场的主导地区。2022 年北美牙科骨移植替代品和屏障膜市场价值为 2.9365 亿美元,预计到 2030 年将达到 5.5238 亿美元;预计在预测期内的复合年增长率为 8.2%。北美牙科骨移植替代品和屏障膜市场分为美国、加拿大和墨西哥。美国在 2022 年占据最大份额,预计在预测期内将继续保持类似的趋势。根据美国牙科协会的数据,老年人口(即 65 岁及以上)正在增长,并且很可能在未来几年成为牙科实践中越来越重要的一部分。与衰老相关的牙科疾病包括口干症(口干症)、根龋和冠龋以及牙周炎。根据美国国家牙科和颅面研究所的数据,美国 30% 的成年人(即 65 岁或以上)患有全牙周炎,7.8% 患有严重牙周炎,34.4% 患有非严重牙周炎。这一因素促进了牙科骨移植替代品和屏障膜市场的区域增长,预计在预测期内将继续保持类似的趋势。
竞争格局和重点公司:
Dentsply Sirona、强生、丹纳赫集团、美敦力、Strauman、Zimmer Dental、Smith & Nephew、Geistlich Pharm、ZimVie Inc.、RTI Surgical 和 Osteogenics Biomedical 是全球牙科骨移植替代品和屏障膜市场的领先公司。
在这些公司中,美敦力和盖氏制药凭借其多样化的产品组合成为排名前两位的公司。
Krey 发展:
牙科骨移植替代品和屏障膜市场中的公司高度采用并购等无机和有机战略。以下列出了一些近期的关键市场发展:
- 2023 年 3 月,ZimVie Inc. 宣布发布其出版物《组织处理对骨异体移植物理化学性质的影响比较》。该文章发表在《国际口腔颌面植入杂志》上。文章展示了其产品的不同组织处理方法的影响,例如 Puros 松质颗粒异体移植骨替代品、Creos、OraGraft 和 MinerOss。
- 2021 年 1 月,登士柏西诺德宣布收购 Datum Dental, Ltd。此次收购使登士柏西诺德能够获得 Datum Dental, Ltd 强大的 OSSIX 生物材料产品组合。这也使得登士柏西诺德能够收购 Datum Dental Ltd 的专利技术 GLYMATRIX。
牙科骨移植替代品和屏障膜市场报告范围
报告属性 | 细节 |
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2022 年市场规模 | 7.2204亿美元 |
2030 年的市场规模 | 13.7992亿美元 |
全球复合年增长率(2022 - 2030 年) | 8.4% |
历史数据 | 2020-2021 |
预测期 | 2023-2030 |
涵盖的领域 | 按产品
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覆盖地区和国家 | 北美
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市场领导者和主要公司简介 |
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- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
Covid-19的影响:
由于牙科诊所和医院的患者数量较少,COVID-19 危机显著降低了牙科骨移植替代品和屏障膜的采用率。在 COVID-19 危机期间,知名市场参与者的收入和利润率大幅下降。牙科就诊人数的减少和选择性手术的推迟直接影响了骨移植替代品和牙科屏障膜产品市场。简而言之,由于主要地区和国家实施了社交距离规则和封锁以限制病毒传播,最终用户的需求大幅下降。因此,疫情对牙科骨移植替代品和屏障膜的市场增长产生了负面影响。然而,2022 年监管的放宽导致牙科医院和专科诊所的入院人数增加。
Dental Bone Graft Substitutes and Barrier Membrane Market Report Scope
Report Attribute | Details |
---|---|
Market size in | US$ 722.04 Million |
Market Size by | US$ 1,379.92 Million |
Global CAGR | 8.4% |
Historical Data | 2020-2021 |
Forecast period | 2023-2030 |
Segments Covered |
By 产品(牙科骨移植替代品(同种异体移植、异种移植、合成骨移植、自体移植、异种移植、脱矿骨基质(DBM-同种异体移植等)和牙科屏障膜(可吸收膜和不可吸收膜))
|
Regions and Countries Covered |
北美(美国、加拿大、墨西哥)
|
Market leaders and key company profiles |
|
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The factors that are driving the growth of market are increasing burden of periodontal diseases and oral cancer and increased market development activities in dental bone graft substitute and barrier membrane market. However, the high cost of products and delays in dental check-ups hinders the market growth.
Dental bone graft substitute and barrier membrane are used for periodontal disease and oral cancer patients in dental bone regeneration procedures. Dental membranes are used in combination with dental bone grafts to promote cell proliferation during the regeneration process. A bone graft is a material that can be implanted and used to promote bone formation, bone healing, skeletal reconstruction, and other procedures. These bone graft materials are used in bone grafting surgical procedures to replace damaged or missing bone (bone graft).
The dental bone graft substitute and barrier membrane market majorly consists of the players such as Geistlich Pharma AG, Medtronic Plc, Dentsply Sirona Inc, Matricel GmbH, ZimVie Inc, Regenity Biosciences Inc, Neoss UK & Ireland Ltd, Institut Straumann AG, CAMLOG Biotechnologies GmbH, and Resorba Medical GmbH.
The List of Companies - Dental Bone Graft Substitute and Barrier Membrane Market
- Geistlich Pharma AG
- Medtronic Plc
- Dentsply Sirona Inc.
- Matricel GmbH
- ZimVie Inc.
- Regenity Biosciences Inc.
- Neoss UK & Ireland Ltd
- Institut Straumann AG
- CAMLOG Biotechnologies GmbH
- Resorba Medical GmbH
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.