[研究报告] 荧光原位杂交(FISH)成像系统市场预计将从 2022 年的 10.84 亿美元增长,到 2030 年预计将达到 19.014 亿美元;预计 2022 年至 2030 年的复合年增长率为 7.3%。
市场洞察和分析师观点:
荧光原位杂交 (FISH) 是一种用于细胞遗传学分析的分子技术。该技术使用荧光探针,这些探针仅与具有高度序列互补性的核酸序列的特定部分结合。FISH 检测染色体上特定 DNA 序列的存在与否。FISH 通常用于查找 DNA/RNA 靶标中的特定特征,以用于医学、遗传咨询和物种识别。推动荧光原位杂交 (FISH) 成像系统市场增长的关键因素包括靶标疾病患病率的上升和体外诊断研发投资的增加。然而,FISH 成像系统和程序的高成本阻碍了市场的增长。
增长动力和限制因素:
FISH 是一种强大的分子细胞遗传学技术,可以对细胞或组织内的特定 DNA 序列进行可视化和定位。该技术彻底改变了遗传学和诊断学领域,为研究人员和临床医生提供了有关遗传异常、染色体重排和各种疾病的宝贵见解。遗传综合征、癌症和其他遗传异常等目标疾病的患病率不断上升,推动了对 FISH 成像系统的需求。根据美国国家医学图书馆的数据,预计 2023 年美国将新增 1.96 例癌症病例和 609,820 例癌症死亡病例。随着这些目标疾病患病率的持续上升,对准确可靠的诊断工具的需求激增。FISH 成像系统提供高分辨率图像,以帮助检测细微的遗传变化,从而实现早期疾病诊断和个性化治疗方法。这些疾病通常涉及基因突变或变异,可以使用 FISH 成像系统准确识别和表征。事实证明,精确绘制细胞内特定基因或 DNA 序列的位置的能力对于理解疾病机制、开发靶向治疗方法和做出明智的临床决策至关重要。
FISH 的一个显著优势在于它能够处理各种样本类型,包括福尔马林固定石蜡包埋组织、细胞学制剂和新鲜组织。这种多功能性使 FISH 成为研究和临床环境中必不可少的工具,可用于识别与白血病、淋巴瘤、实体瘤和先天性疾病等疾病相关的遗传标记。
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荧光原位杂交 (FISH) 成像系统市场受到体外诊断 (IVD) 相关研发 (R&D) 活动持续投资的进一步推动。凭借其在细胞环境中可视化特定 DNA 序列的独特能力,FISH 技术已成为现代诊断的关键程序,特别是在检测遗传疾病和罕见疾病方面。IVD 研发资金的激增催化了 FISH 成像系统的变革性进步,使研究人员能够创建尖端平台,提供增强的图像质量和支持简化自动化的功能,最终实现更准确、更快速的诊断过程。PNA FISH 是一种使用 FISH 和肽核酸 (PNA) 探针的新型诊断方法,它将传统染色程序的简便性与 PNA 探针的卓越性能相结合,提供对传染病的快速准确诊断,这使得 PNA FISH 适合常规应用,并使临床微生物学实验室能够在使用传统生化方法无法实现的时间范围内报告患者治疗的重要信息。
然而,由于 FISH 成像分析的成本相对较高,因此在癌症检测中不太常用。除了设备成本外,与试剂、其他消耗品和专业人员任命相关的费用也会增加基于 FISH 成像的评估总成本。例如,在美国,通过 IHC 检测 ALK 基因非小细胞肺癌每次测试的成本为 90.07 美元,在欧洲为 68.69 美元,这低于通过 FISH 和 IHC 进行独立或并行测试(在美国每次测试的成本约为 441.85 美元,在欧洲为 279.46 美元)。因此,程序和系统的高成本限制了荧光原位杂交 (FISH) 成像系统市场的增长。
报告细分和范围:
“全球荧光原位杂交 (FISH) 成像系统市场”根据产品、应用和最终用户进行细分。根据产品,市场细分为仪器、耗材、配件和软件。在应用方面,荧光原位杂交 (FISH) 成像系统市场细分为癌症诊断、遗传病诊断、传染病诊断等。根据最终用户,市场细分为诊断实验室、合同研究组织、制药和生物技术公司等。根据地理区域,荧光原位杂交 (FISH) 成像系统市场分为北美(美国、加拿大和墨西哥)、欧洲(德国、法国、意大利、英国、俄罗斯和欧洲其他地区)、亚太地区(澳大利亚、中国、日本、印度、韩国和亚太其他地区)、中东和非洲(南非、沙特阿拉伯、阿联酋和中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷和南美洲和中美洲其他地区)。
节段分析:
荧光原位杂交 (FISH) 成像系统市场按产品细分为仪器、耗材、配件和软件。耗材部分在 2022 年占据最大市场份额,预计在 2022-2030 年期间将实现最高复合年增长率。耗材是荧光原位杂交 (FISH) 成像系统市场中最有前景的部分,将在未来几年带来巨大增长。FISH 耗材包括杂交缓冲液、探针、标签检测试剂盒、信号放大检测试剂盒等。Abbott、F. Abnova 和 Thermo Fisher Scientific 等制造商的存在增强了耗材部分的市场。这些产品经常用于各种研究诊断过程,预计将推动消费。因此,各种市场参与者提供探针和试剂盒以及市场参与者的技术进步可能会在未来几年推动该细分市场的发展。
根据应用,荧光原位杂交 (FISH) 成像系统市场细分为癌症诊断、遗传病诊断、传染病诊断等。癌症诊断部分在 2022 年占据了最大的市场份额,预计在 2022-2030 年期间将实现最高复合年增长率。FISH 技术极大地促进了癌症诊断。FISH 成像系统可以寻找基因变化并帮助检测异常。根据英国癌症研究中心的数据,FISH 检测用于诊断多种癌症,包括乳腺癌、淋巴瘤、肺癌、前列腺癌、慢性淋巴细胞白血病 (CLL)、急性淋巴细胞白血病 (ALL)、急性髓细胞白血病 (AML)、慢性髓细胞白血病 (CML)、骨髓瘤、尤文氏肉瘤和黑色素瘤皮肤癌。
根据最终用户,荧光原位杂交 (FISH) 成像系统市场细分为诊断实验室、合同研究组织、制药和生物技术公司等。诊断实验室部门在 2022 年占据最大市场份额,预计在 2022-2030 年期间将实现最高复合年增长率。诊断实验室参与各种研究项目,以开发用于荧光原位杂交 (FISH) 成像过程的多种技术和产品。研究和技术的前所未有的发展为医疗保健和生命科学领域的转型创造了潜力。荧光原位杂交 (FISH) 成像系统的临床应用非常广泛,为增强慢性病的诊断和治疗能力提供了机会。它们在基因发现和罕见遗传疾病的诊断方面具有巨大潜力。这些技术越来越多地用于分析影响常见疾病(如癌症、高血压、糖尿病和肾脏疾病)发展的罕见和常见遗传因素。
区域分析:
根据地域划分,全球荧光原位杂交 (FISH) 成像系统市场分为五个主要区域:北美、欧洲、亚太、南美和中美以及中东和非洲。2022 年,北美在全球荧光原位杂交 (FISH) 成像系统市场规模中所占份额最大。预计亚太地区在 2022-2030 年期间的复合年增长率最高。
据估计,在预测期内,美国将占据最大的荧光原位杂交 (FISH) 成像系统市场份额。美国在北美的荧光原位杂交 (FISH) 成像系统市场中占有相当大的份额。对分子遗传学和细胞遗传学先进诊断工具的需求不断增长,以及遗传疾病和癌症患病率的上升,推动了美国采用荧光原位杂交 (FISH) 成像系统。根据美国癌症协会 2022 年发布的数据,美国诊断出近 190 万例癌症病例,报告了 609,360 例癌症死亡病例。这些系统提供遗传物质的高分辨率成像,使研究人员和临床医生能够更准确地检测染色体异常和基因突变。此外,对个性化医疗和靶向治疗的日益关注导致涉及基因分析的研究活动激增,从而增加了对 FISH 成像系统的需求。这些系统能够直接在细胞内提供有关基因序列的详细空间信息,这在研究和临床应用中都已被证明是无价的。 FISH 成像系统最近因其技术进步而广受欢迎,例如自动化程度提高、吞吐量提高和图像分析软件增强。因此,实验室和医疗机构能够更好地处理大量样本并高效地生成精确结果。因此,对分子遗传学和细胞遗传学先进诊断工具的需求不断增长,以及遗传疾病和癌症患病率不断上升,推动了美国荧光原位杂交 (FISH) 成像系统市场的发展。
行业发展和未来机遇:
以下列出了全球荧光原位杂交 (FISH) 成像系统市场的主要参与者采取的各种举措:
- 2023 年 5 月,辉瑞与赛默飞世尔科技公司合作,帮助拉丁美洲、非洲、中东和亚洲 30 多个国家/地区的肺癌和乳腺癌患者提高当地获得新一代测序 (NGS) 检测的机会,这些国家/地区的高级基因组检测此前受到限制或无法获得。获得当地 NGS 检测的机会有助于更快地分析相关基因,让医疗保健提供者能够为特定患者选择最佳药物。
- 2023 年 4 月,安捷伦科技公司与韩国 Theragen Bio 签署了谅解备忘录。作为合作协议的一部分,安捷伦和 Theragen Bio 结合各自在癌症基因组分析设计、工程知识和软件专业知识方面的优势,推动本地化分析能力并加速治疗决策。
- 2023 年 4 月,MetaSystems Probes GmbH 推出了四款新型 XCyting New MetaSystems 探测器——XL t(11;14) CCND1/IGH DF、XL CCND3/IGH DF、XL CUX1/EZH2/7cen 和 XL DiGeorge TBX1。
- 2022 年 5 月,MetaSystems Probes GmbH 在其血液学和肿瘤学产品组合中推出了三种新的 XCyting 基因座特异性分离探针——XL TCL1 BA、XL SPI1 BA 和 XL CSF1R BA。XL TCL1 BA 旨在检测涉及几种 T 细胞幼淋巴细胞白血病 (T-PLL) 病例中描述的重排的 TCL1 基因簇位点。XL SPI1 BA 适用于检测儿童 T 细胞急性淋巴细胞白血病 (T-ALL) 病例中涉及重排的 SPI1 基因位点。XL CSF1R BA 是 ALL 疾病高风险子集中描述的涉及多种重排的主要基因之一,这些疾病占 B 细胞前体 ALL。
- 2021 年 12 月,BioGenex Laboratories Inc 推出了三种用于癌症诊断的新型主要免疫组织化学 (IHC) 抗体——CD8A、CD56 和 CD163。
荧光原位杂交 (FISH) 成像系统市场区域洞察
Insight Partners 的分析师已详尽解释了预测期内影响荧光原位杂交 (FISH) 成像系统市场的区域趋势和因素。本节还讨论了北美、欧洲、亚太地区、中东和非洲以及南美和中美洲的荧光原位杂交 (FISH) 成像系统市场细分和地理位置。
- 获取荧光原位杂交 (FISH) 成像系统市场的区域特定数据
荧光原位杂交 (FISH) 成像系统市场报告范围
报告属性 | 细节 |
---|---|
2022 年市场规模 | 10.8亿美元 |
2030 年的市场规模 | 19亿美元 |
全球复合年增长率(2022 - 2030 年) | 7.3% |
史料 | 2020-2021 |
预测期 | 2023-2030 |
涵盖的领域 | 按产品
|
覆盖地区和国家 | 北美
|
市场领导者和主要公司简介 |
|
荧光原位杂交 (FISH) 成像系统市场参与者密度:了解其对业务动态的影响
荧光原位杂交 (FISH) 成像系统市场正在快速增长,这得益于终端用户需求的不断增长,而这些需求又源于消费者偏好的不断变化、技术进步以及对产品优势的认识不断提高等因素。随着需求的增加,企业正在扩大其产品范围,进行创新以满足消费者的需求,并利用新兴趋势,从而进一步推动市场增长。
市场参与者密度是指在特定市场或行业内运营的企业或公司的分布情况。它表明在给定市场空间中,相对于其规模或总市场价值,有多少竞争对手(市场参与者)存在。
荧光原位杂交 (FISH) 成像系统市场的主要公司有:
- 欧洲克隆公司
- TissueGnostics GmbH
- 安捷伦科技公司
- 台湾上元科技有限公司
- BioGenex 实验室公司
免责声明:上面列出的公司没有按照任何特定顺序排列。
- 获取荧光原位杂交 (FISH) 成像系统市场顶级关键参与者概览
竞争格局和重点公司:
Euroclone SpA、TissueGnostics GmbH、安捷伦科技公司、Abnova Taiwan Corp、BioGenex Laboratories Inc、Leica Biosystems Nussloch GmbH、MetaSystems Probes GmbH、Bio-View Ltd、Thermo Fisher Scientific Inc、Applied Spectral Imaging 和 PerkinElmer Inc 是荧光原位杂交 (FISH) 成像系统市场上的知名企业。这些公司专注于新技术、现有产品的改进和地域扩张,以满足全球日益增长的消费者需求,并增加其专业产品组合的产品范围。
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Segment Covered
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Frequently Asked Questions
Fluorescence in situ hybridization (FISH) is a molecular technique for cytogenetic analysis. This technique uses fluorescent probes that bind to only particular parts of a nucleic acid sequence with a high degree of sequence complementarity. FISH detects the presence or absence of specific DNA sequences on chromosomes. FISH is often used to find specific features in DNA/RNA targets for medicine, genetic counseling, and species identification.
The fluorescence in-situ hybridization (FISH) imaging systems market majorly consists of the players, including Euroclone SpA, TissueGnostics GmbH, Agilent Technologies Inc, Abnova Taiwan Corp, BioGenex Laboratories Inc, Leica Biosystems Nussloch GmbH, MetaSystems Probes GmbH, Bio-View Ltd, Thermo Fisher Scientific Inc, Applied Spectral Imaging, and PerkinElmer Inc.
Factors such as the rising prevalence of target disorders and the increasing R&D investments in in-vitro diagnostics propel market growth.
The fluorescence in-situ hybridization (FISH) imaging systems market was valued at US$ 1,084.02 million in 2022.
The fluorescence in-situ hybridization (FISH) imaging systems market, by end user, is segmented into diagnostic laboratories, contract research organizations, pharmaceutical and biotechnological companies, and others. The diagnostic laboratories segment held a larger market share in 2022, and the same segment is anticipated to register a higher CAGR.
The fluorescence in-situ hybridization (FISH) imaging systems market is expected to be valued at US$ 1,901.38 million in 2030.
The global fluorescence in-situ hybridization (FISH) imaging systems market, by application, is segmented into cancer diagnosis, genetic disease diagnosis, infectious disease diagnosis, and others. The cancer diagnosis segment held a larger market share in 2022, and the same segment is anticipated to register a higher CAGR.
The fluorescence in-situ hybridization (FISH) imaging systems market, by services, is segmented into pharmacokinetics, biomarkers, immunogenicity, virology testing, cell-based assays, and others. The cell-based assays segment held a larger market share in 2022. Also, the same segment is anticipated to register a higher CAGR.
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The List of Companies - Fluorescence In-Situ Hybridization (FISH) Imaging Systems Market
- Euroclone SpA
- TissueGnostics GmbH
- Agilent Technologies Inc
- Abnova Taiwan Corp
- BioGenex Laboratories Inc
- Leica Biosystems Nussloch GmbH
- MetaSystems Probes GmbH
- Bio-View Ltd
- Thermo Fisher Scientific Inc
- Applied Spectral Imaging
- PerkinElmer Inc
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.