高内容放映市场展望报告| 2031 年规模、份额和趋势

  • Report Code : TIPRE00004161
  • Category : Biotechnology
  • No. of Pages : 150
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High Content Screening Market Key Findings by 2031

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[研究报告]高内容放映市场价值从2022年的16.7096亿美元增至2030年的28.6156亿美元;预计 2022 年至 2030 年复合年增长率为 7.2%。

市场洞察和分析师观点:

高内涵筛选 (HCS) 是一种用于细胞生物学应用的高通量格式,它结合了大规模应用的定量数据分析和自动成像,包括系统生物学和药物发现。目前,HCS主要用作荧光成像技术,通常同时测量少量荧光染料。近年来,由于自动筛选技术和荧光显微镜的进步,药物发现行业中 HCS 的使用大幅增加。 HCS 使用自动荧光显微镜对单个细胞的亚细胞和分子活动进行成像,使快速筛选化学或 siRNA 文库成为可能。 HCS 最明显的用途是初步筛选可能的先导化合物、可进一步细化为候选治疗药物的化合物,或测量难以用单一终点测量的细胞形态或其他细胞活性,包括空间定位的蛋白质。< /span>

增长动力和挑战:

研究的增加开发活动正在推动市场的增长。高内涵筛选为学术和药物问题提供生物学答案。肝毒性、心脏毒性、肾毒性、发育毒性、遗传毒性和神经毒性是采用 HCS 方法的体外毒理学应用。这使得最近创建的几种细胞分析模型成为可能,例如芯片组织方法、三维 (3D) 细胞模型和诱导多能干细胞 (iPSC)。 HCS 还通过图像数据分析工具与高内涵分析和基因组编辑方法(例如 CRISPR/Cas9)结合使用。这些方法极大地促进了对生物过程的理解、创造药物和简化毒理学研究。

由于药物发现的研究和开发,HCS 市场正在全球范围内扩张。例如,公立赠地研究型大学普渡大学于 2021 年 2 月发表了一份报告,评估了 IL-27 的影响,IL-27 是一种由亚基 IL-27p28 和 EBI3(EB 病毒诱导基因 3)组成的异二聚体细胞因子。 ,关于 TC2R 前列腺癌细胞基因表达的变化。使用高通量测序 (HCS) 发现,TC2R 前列腺癌细胞的基因表达因 RNAi(RNA 干扰)而改变。 RNAi 的目标是编码这些特定蛋白质的信使 RNA。

尽管现代计算机具有巨大的处理能力、快速的连接性和价格合理的数据存储,但仍然有一些应用 HCS 时必须面临的重要技术挑战。 HCS 从业者经常发现需要第三方分析软件来提高不频繁测试的效率,尽管许多仪器都配备了功能强大、用户友好的图像分析软件。此外,由于缺乏图像和数据格式的标准,许多数据存储、数据传输和数据注释的解决方案无法在平台之间很好地过渡。

战略见解

报告细分和范围:

高内涵筛选市场分为产品、应用和最终用户。按产品划分,市场分为仪器、消耗品、软件、服务和配件。根据应用,高内涵筛选市场分为初级筛选和二级筛选、目标识别和验证、毒性研究、化合物等。就最终用户而言,高内涵筛选市场分为制药和生物技术公司、合同研究组织(CRO)以及学术和政府机构。高内容放映市场根据地理位置分为北美(美国、加拿大和墨西哥)、欧洲(法国、德国、意大利、英国、西班牙、比荷卢经济联盟、奥地利和欧洲其他地区)、亚太地区(澳大利亚) 、中国、日本、印度、韩国、马来西亚、印度尼西亚和亚太地区其他地区)、中东和非洲非洲(沙特阿拉伯、阿联酋、南非以及中东和非洲其他地区)以及南美和非洲中美洲(巴西、阿根廷、南美洲和中美洲其他地区)

分段分析:

根据产品,全球高内涵筛查市场分为仪器、耗材、软件、服务和配件。到 2022 年,仪器细分市场将占据最大的市场份额。由于高内涵筛选技术用于可视化和解释细胞图像,因此它们对于毒理学、药物开发和基础细胞生物学研究至关重要。这些最先进的设备具有许多功能,例如高通量能力、自动成像和分析以及进行困难实验的能力。

高内涵筛选软件用于图片分析、数据管理和测定设计。得益于人工智能和机器学习的突破,使用可以自动化某些高内容筛选过程的复杂软件可以减少手动分析的时间和成本。预计对高内涵筛查软件的强劲需求的另一个因素是人们对精准和个性化医疗的兴趣日益浓厚,这有助于开发专门针对个体患者需求的药物。

按照应用,高内涵筛选市场分为目标识别和验证、初级筛选和二级筛选、毒性研究、化合物等。预计到 2022 年,毒性研究部分将以最高复合年增长率增长。由于高内涵筛选可以识别损害细胞的化合物,因此对于毒性研究至关重要。可以进行一系列测试来评估物质对细胞活力、增殖和凋亡的影响。高内涵筛选的软件和技术可用于这些测定。此外,高内涵筛选可帮助研究人员通过检查化学品的毒性过程,在药物开发过程的早期发现任何安全问题。

对于最终用户来说,高内涵筛选市场是分为学术和政府机构、制药和生物技术公司以及合同研究组织 (CRO)。到 2022 年,制药和生物技术公司领域占据最大的市场份额。高内涵筛选在该市场占据主导地位,因为生物技术和制药行业在临床前和临床研究中广泛使用它。它在学术界和制药行业的使用已经发展到现在成为药物研究和发现的重要工具。由于细胞分析技术已经发展到三维 (3D) 培养、基因组编辑工具(例如 CRISPR/Cas9)和诱导多能干细胞 (iPSC) 的水平,高内涵分析在帮助药物开发方面具有更大的潜力。 )。

高内容放映市场(按产品) 2022年和2030年

区域分析:

根据地理位置,高内容放映市场分为五个关键区域——北美、欧洲、亚太地区、南美洲和南美洲。中美洲、中东和非洲非洲。预计亚太地区在预测期内的复合年增长率最高。由于中国、印度等新兴国家药物研发需求不断增长,亚太地区高内涵筛选产品市场预计将快速增长。

< span>高内涵筛选市场趋势:

基于自动显微镜的高内涵筛选

基于自动显微镜的高内涵筛选最近获得了巨大的发展动力,因为它能够同时研究复杂生物系统中的许多特征。 HCS 应用于整个临床前药物发现流程。它可以识别和验证新的药物靶点或先导化合物,预测体内毒性,并建议化合物的途径或分子靶点。 HCS 还用于支持临床试验,例如伴随诊断。制药公司正在实施用于测试化学品和复杂物质的可能毒性的后续高内涵筛查(HCS)解决方案,以通过降低成本和时间来改进体外毒性测试。越来越多的CRO提供HCS外包服务并将HCS应用于个性化医疗,这是市场的一个重要趋势。高内涵筛选显微镜是一项快速发展的技术,可用于提取有关细胞形态和功能的丰富定量信息。

竞争格局和主要公司:

全球高内容筛查市场的一些知名参与者包括 GE Healthcare、Danaher Corporation、Thermo Fisher Scientific Inc.、 PerkinElmer、Tecan Group、Bio Tek Instruments Inc.、Becton、Dickinson、Bio-Rad Laboratories、横河电机公司和 Merk Millipore。这些公司专注于开发新技术、改进现有产品、扩大其地理覆盖范围以满足全球不断增长的消费者需求,并扩大其专业产品组合的产品范围。在全球高内涵筛选市场运营的公司实施各种无机和有机策略。下面提到其中一些:

  • 2022 年 9 月,BD(Becton、Dickinson 和 Company)推出了 BD Research Cloud,这是一种基于云的软件解决方案,旨在简化流式细胞术工作流程,为跨学科(包括病毒学、免疫学、肿瘤学和传染病监测)工作的科学家提供更高质量的实验,让他们更快地获得见解。
  • 3 月2022 年,贝克曼库尔特生命科学公司推出了一款强大的解决方案,解决临床流式细胞术中的手动样品制备和数据管理瓶颈:CellMek SPS。这种全自动样品制备系统 (SPS) 可为多种样品类型提供按需处理,以帮助实验室扩展其能力。    
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

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to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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to country scope.

The List of Companies

1. GENERAL ELECTRIC
2. Danaher
3. Perkinelmer, Inc.
4. Thermo Fisher Scientific Inc.
5. BD
6. BioTek Instruments, Inc.
7. Bio-Rad Laboratories, Inc.
8. Tecan Trading AG
9. Merck KGaA
10. Yokogawa Electric Corporation

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

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  • Validates and strengthens in-house secondary research findings
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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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