mRNA Sequencing Market Growth, Size, Share, Trends by 2030
市场洞察和分析师观点:
mRNA 测序等因素加快了罕见疾病的诊断速度,创新产品的推出推动了 mRNA 测序市场的增长。< br>增长动力:
mRNA 测序加快罕见疾病的诊断率
瑞典 Orphan Biovitrum AB 出版物统计显示,目前全球已发现超过 7,000 种估计罕见/孤儿疾病。其中,只有5%的药物在全球获得批准。因此,罕见疾病的治疗带来了巨大的医疗费用负担。医疗费用约为。比其他疾病高10倍。例如,在美国,373种罕见疾病每年造成的费用达2.2万亿美元。据估计,所有已知罕见疾病的医疗费用每年可能在 7.2-8.6 万亿美元之间。因此,与诊断困难和延误、缺乏治疗方法、新疗法的开发以及有利的监管和可及性相关的罕见疾病将导致创新技术的发展。 Illumina 的“全基因组测序(WGS)”就是这样一个例子,它可以改善罕见遗传疾病的诊断。与其他基因检测方法相比,全基因组测序具有三个关键优势,即操作效率提高、制造成本低和诊断成本低。此外,WGS 是在单次检测中检测多种变异类型的最全面的测试,这对罕见疾病非常重要。
因此,对 mRNA 测序识别罕见疾病的需求不断增长,导致 mRNA 测序市场规模不断增长。< br>
报告细分和范围:
“mRNA 测序市场分析”是通过考虑以下细分进行的:类型、方法和最终用户。
细分分析:
按类型中,mRNA 测序市场分为产品和服务。类型细分进一步分为产品和服务。耗材细分市场在 2022 年占据最大的 mRNA 测序市场份额。预计服务细分市场在预测期内的复合年增长率最高,为 13.9%。
高通量 mRNA 测序是生命科学实验室转录组发现和识别差异基因表达分析的标准技术。因此,制造商推出的创新产品将促进消耗品领域的增长。 PacBio 的“SMRTbell 制备试剂盒 3.0 和结合试剂盒 3.1 和 3.2”是用于 mRNA 测序的创新耗材的示例。此外,PacBio 于 2023 年 10 月宣布推出新产品,用于开发高质量和准确的测序解决方案“Kinnex RNA 试剂盒”。 Kinnex RNA 试剂盒提高了全长 RNA、单细胞 RNA 和 16S rRNA 测序的通量。这些 Kinnex 试剂盒基于“MAS-seq 方法”,客户可以将长链文库转录为短链,提高通量,并使测序过程更具成本效益。
按方法划分的 mRNA 测序市场 – 2022 年和 2030 年< br>技术进步:mRNA测序市场的新趋势
随着技术的涌入,mRNA疫苗和治疗方法对满足未满足的医疗需求具有重要影响。例如,新兴的mRNA测序技术将有助于癌症研究。 Illumina 的癌症转录组 mRNA 测序就是这样的一个例子,它提供了有关癌症基因表达和基因融合的功能信息,帮助科学家了解肿瘤的分类和进展。因此,癌症 mRNA 序列可以帮助科学家:
· 确定癌症样本中的变异表达
· 识别与肿瘤类型、个体肿瘤和单细胞相关的基因表达特征和突变谱
· 寻找新的调节基因表达的小RNA
·识别染色体易位产生的基因融合
同样,SARS-CoV-2疫苗的开发也涉及mRNA技术。因此,序列确认是 mRNA 治疗和疫苗制造过程中的关键活动。因此,赛默飞世尔科技的“Sanger Sequencing”就是一种用于开发mRNA疫苗的技术。对于 mRNA 疫苗的制造,在操作 DNA 和 RNA 中间体的许多生产阶段都需要准确性,其中桑格测序提供了关键属性。这些属性包括简单的工作流程、短的临床时间和可扩展的工作流程。此外,赛默飞世尔科技利用桑格测序技术开发了一种简化的 mRNA 测序方案,无需在循环测序前进行 PCR 扩增,从而缩短了临床结果时间并最大限度地减少了错误。因此,mRNA 测序的技术进步最终将为市场增长开辟新的途径。
区域分析:
报告的范围集中在北美、欧洲、亚太地区、南美洲和中美洲以及中东&非洲。 2022年,北美占据最大的mRNA测序市场份额。该地区的市场是由主要市场参与者的存在推动的。此外,各制药和生物技术公司以及学术和研究机构的广泛研发预计将刺激北美 mRNA 测序市场的增长。美国是北美市场的最大贡献者。它主要是由不断增长的生物技术行业推动的,其特点是技术进步。此外,美国制药和生物技术公司增加研发投资以改善临床试验结果并确保患者安全刺激市场增长。
行业发展和未来机遇:
mRNA 测序市场预测可以帮助利益相关者市场规划他们的增长战略。以下列出了 mRNA 测序市场领先企业的一些战略发展:
· 2023 年 11 月,Lexogen 宣布推出“LUTHOR 高清晰度单细胞 3 mRNA-Seq 试剂盒”产品。 LUTHOR HD 可以检测细胞内的单个基因拷贝,使研究人员能够直观地看到每个细胞的完整转录组,以高倍率捕获 95% 的表达基因。
· 2023 年 11 月,PacBio 宣布扩展“多重阵列测序” (MAS-Seq) 用于新的检测。这项开发是在成功的“MAS-Seq”级联技术的基础上开发的,该技术能够实现经济有效的单细胞亚型测序。该技术最终拥有批量 RNA 测序和 16 S rRNA 等关键应用为客户提供经济高效的试剂盒解决方案和端到端软件。
竞争格局和主要公司:
Takara Bio Inc.、Illumina, Inc.、QIAGEN、F. Hoffmann-La Roche Ltd、Quantabio 和 QIAGEN。 Zymo Research Corporation、baseclick GmbH、Paragon Genomics, Inc.、Yasen Biotechnology (上海) Co., Ltd.、Novogene Co., Ltd 和 Norgen Biotek Corp 都是 mRNA 测序市场报告中介绍的知名公司。开发新技术、升级现有产品并扩大地域影响力,以满足全球不断增长的消费者需求。
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Frequently Asked Questions
The CAGR value of the mRNA sequencing market during the forecasted period of 2022-2030 is 13.2%.
Key factors that are driving the growth of this market are identification of mRNA sequencing for diagnosis of rare diseases and innovative product launches is expected to boost the market growth for the mRNA sequencing over the years.
The product segment held the largest share of the market in the global mRNA sequencing market and held the largest market share in 2022.
Illumina, Inc. and F. Hoffmann-La Roche Ltd are the top two companies that hold huge market shares in the mRNA sequencing market.
The next-generation sequencing segment dominated the global mRNA sequencing market and held the largest market share in 2022.
mRNA sequencing is a powerful technique that is used to investigate the transcriptome status of a gene including transcription level and splicing variants. Currently, several mRNA sequencing methods have been developed and three are commercially available RNA-seq library preparation kits, traditional "TruSeq", and a full-length double-stranded cDNA methods for transcriptome analysis.
The mRNA sequencing market majorly consists of the players such Takara Bio Inc., Illumina, Inc., QIAGEN, F. Hoffmann-La Roche Ltd, Quantabio, Zymo Research Corporation, baseclick GmbH, Paragon Genomics, Inc., Yeasen Biotechnology (Shanghai) Co.,Ltd. Novogene Co, Ltd and Norgen Biotek Corp, and amongst others.
Global mRNA sequencing market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa and South & Central America. North America held the largest market share of the mRNA sequencing market in 2022.
The List of Companies - mRNA Sequencing Market
- 1. Takara Bio Inc.
- 2. Illumina, Inc.
- 3. QIAGEN
- 4. F. Hoffmann-La Roche Ltd
- 5. Quantabio, Zymo Research Corporation
- 6. baseclick GmbH
- 7. Paragon Genomics, Inc.
- 8. Yeasen Biotechnology (Shanghai) Co.,Ltd.
- 9. Novogene Co, Ltd
- 10. Norgen Biotek Corp
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