类器官市场基于(主要地区、市场参与者、规模和份额)- 预测至 2030 年

  • Report Code : TIPRE00017616
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 190
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Organoids Market Size Report | Analysis and Forecast 2030

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[研究报告] 2022 年类器官市场价值为 25.0728 亿美元,预计到 2030 年将达到 122.0615 亿美元。预计2022-2030 年期间的复合年增长率为 21.9%。

 

市场洞察和分析师观点:

由于对肿瘤建模和生物库的需求不断增长、个性化药物的采用日益增加以及对开发动物测试模型替代品的关注度不断提高,类器官市场规模正在迅速增长。然而,将类器官纳入现有工作流程的问题以及熟练专业人员的短缺阻碍了市场的增长。

类器官是由体外干细胞生长而成的微观自组织 3D 结构。它们反映了其体内对应器官的各种结构和功能特征。这种多用途技术已产生了几种新型人类癌症模型。现在可以从患有各种癌症的个体的肿瘤组织开始创建无限扩增的类器官。或者,基于 CRISPR 的基因改造允许通过将多种癌症基因改变引入正常类器官来设计癌症的类器官模型。肿瘤类器官与免疫细胞和成纤维细胞相结合,成为癌症微环境的模型,从而实现免疫肿瘤学应用。此外,最近的研究证明类器官在个性化医疗方法中占有一席之地。这项研究将促进预防、进展和治疗策略的制定。新技术的商业化将在未来几年提升市场价值。

 

增长动力和挑战:

精准医疗或个性化医疗是一种根据目标反应或疾病风险为个体患者量身定制医疗程序或药物的医疗模式。根据个性化医疗联盟 ( PMC ) 发布的一项研究,个性化药物仅占 2005 年 FDA 批准的新分子实体的 5%,而到 2016 年则占到 25% 以上。此外,产品线中约有 42% 的所有化合物和近 73% 的肿瘤化合物有可能成为精准药物。此外,生物制药公司在过去五年中对个性化药物的研发投入几乎增加了一倍,未来五年可能还会增长 33% 左右。生物制药研究人员还预测未来五年个性化药物的开发将增长 69%。根据PMC的最新报告(2021年发布),在美国,市场上的个性化药物数量已从2016年的约132种增加到2020年的286种。该数据是通过跟踪PMC自2008年以来的个性化药物数量而分享的这些优势凸显了肿瘤类器官在个性化癌症治疗中的巨大潜力,特别是在临床前药物筛选和预测患者对所选治疗方案的反应方面。

由于制造类器官需要大量资金和时间,因此在正在进行的药物筛选和发现活动中采用类器官的现象有限。此外,缺乏 3D 细胞培养研究基础设施和各种技术挑战阻碍了将类器官纳入现有研究工作流程。尽管类器官在系统小型化和降低药物发现和开发成本方面显示出巨大的潜力,但预计这项技术需要几年时间才能完全取代传统模式。在这种情况持续下去之前,类器官制造商将见证零星增长,并可能被传统技术提供商边缘化。

 

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类器官市场: Market:

Organoids Market: Strategic Insights

Organoids Market

  • CAGR (2022 - 2030)
    21.9%
  • Market Size 2022
    US$ 2.51 Billion
  • Market Size 2030
    US$ 12.21 Billion

Market Dynamics

GROWTH DRIVERS
  • 肿瘤建模和生物银行需求不断增长
  • 个性化药物应用日益广泛
  • 动物测试模型替代品开发日益受到关注
FUTURE TRENDS
  • 将类器官与器官芯片相结合
OPPORTUNITIES
  • 专注于药物研发活动

Key Players

  • STEMCELL Technologies Inc
  • Cellesce Ltd
  • Hubrecht Organoid Technology
  • Definigen
  • Organoid Therapeutics
  • PeproTech, Inc
  • Thermo Fisher Scientific Inc
  • Corning Inc
  • Merck KGaA

Regional Overview

  • 北美(美国、加拿大、墨西哥)
  • 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
  • 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
  • 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
  • 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)

Market Segmentation

器官类型(肠、肝、胃、胰腺、肺、脑、肾等)
    应用(生物疾病研发、传染病病理学、再生医学、药物研发及个性化医疗、药物毒性及疗效测试等)
      来源(多能干细胞和器官特异性成体干细胞)
        类型(仪器、耗材和服务)

          类器官市场 Market

          • 复合年增长率(2022 - 2030 年)
            21.9%
          • 2022 年市场规模
            25.1 亿美元
          • 2030 年市场规模
            122.1 亿美元

          市场动态

          增长动力
          • 肿瘤建模和生物样本库需求不断增长
          • 个性化药物的采用日益广泛
          • 日益关注开发动物测试模型的替代品
          未来的趋势
          • 将类器官与器官芯片相结合
          机会
          • 专注于药物研发活动

          关键人物;主力;重要一员

          •  
          • 干细胞技术公司
          • 赛莱斯有限公司
          • Hubrecht 类器官技术
          • 迪菲尼根
          • 类器官治疗
          • PeproTech 公司
          • 赛默飞世尔科技公司
          • 康宁公司
          • 默克公司

          区域概况

          • 北美
          • 欧洲
          • 亚太
          • 南美洲和中美洲
          • 中东和非洲

          市场细分

          器官类型
          • 胰腺
          • 其他的
          应用
          • 生物疾病的发展
          • 传染病病理学
          • 再生医学
          • 药物研发和个性化医疗
          • 药物毒性和疗效测试
          • 其他的
          来源
          • 多能干细胞和器官特异性成体干细胞
          类型
          • 仪器
          • 耗材
          • 服务
          • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

           

          报告细分和范围:

          类器官市场根据器官类型、应用、来源、类型和地理位置进行细分。根据器官类型,市场分为肠、肝、胃、胰腺、肺、脑、肾和其他。按器官类型划分的整体市场增长归因于产品发布的增加和对肿瘤学研究的需求增加。

          根据类型,市场分为仪器、耗材和服务。2022 年,耗材部分占据了最大的市场份额,预计未来几年将以最快的速度增长。根据地域,市场分为北美(美国、加拿大和墨西哥)、欧洲(英国、德国、法国、意大利、西班牙和欧洲其他地区)、亚太地区(中国、日本、印度、韩国、澳大利亚和亚太其他地区)、中东和非洲(阿联酋、沙特阿拉伯、南非和中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷和南美洲和中美洲其他地区)。

           

          节段分析:

          根据器官类型,类器官市场细分为肠、肝、胃、胰腺、肺、脑、肾等。2022 年,肠道部分占据了最大的市场份额,预计在 2022-2030 年期间将以显着的复合年增长率增长。肠类器官是人类肠上皮的 3D 体外模型,可用于针对患者的体外研究,以研究肠上皮的特性。全球成熟和新兴参与者的存在广泛推动了类器官市场的发展。

          根据应用,类器官市场细分为发育生物学疾病、传染病病理学、再生医学、药物毒性和疗效测试、药物发现和个性化医疗等。2022 年,发育生物学疾病领域按应用占据最大的市场份额。预计未来几年将以最快的速度增长。

          根据来源,类器官市场分为多能干细胞和器官特异性成体干细胞。2022 年,多能干细胞领域占据了更大的市场份额,预计未来几年将以更快的速度增长。

          类器官市场根据类型分为仪器、耗材和服务。2022 年,耗材部分占据了最大的市场份额,预计未来几年将以最快的速度增长。

           

          区域分析:

          根据地域,类器官市场分为北美、欧洲、亚太地区、中东和非洲以及南美和中美洲。北美是市场增长的最大贡献者,亚太地区是增长最快的地区。北美市场的增长归因于医疗支出增加、医疗技术进步以及该地区大学正在进行的研究等因素。根据对北美国家进行分析的结果,美国是最大的市场份额持有者。在预测期内,预计类器官研究活动的增加将推动该地区的市场发展。例如,总部位于美国的辛辛那提儿童医院医疗中心建立了干细胞和类器官医学中心 (CuSTOM)。CuSTOM 与一些工业和慈善合作伙伴合作,利用各种类器官平台整合了 15 多个联合研究教师小组。CuSTOM 的初步目标是基于其强大的内胚层开发专业知识,开发用于药物测试和移植的胃肠道和肝脏类器官系统。

           

          行业发展和未来机遇:

          以下列出了类器官市场主要参与者的各种举措:

          1. 2023 年 2 月,美国公司赛默飞世尔科技与韩国公司 Celltrio 合作开发了一款适用于生物治疗客户的全自动细胞培养系统。此次合作将整合赛默飞世尔科技 Momentum 工作流程调度软件与 Celltrio RoboCell 自动化平台,以满足市场对高通量自动化细胞系培养和维护的需求。
          2. 2021年8月,STEMCELL Technologies(一家总部位于美国的公司)与 Hubrecht Organoid Technology (HUB) 签署了一项合同,将组织来源的类器官(包括肺、肝和肠类器官)用于临床前毒理学筛选以及由 STEMCELL 公司旗下的合同检测服务提供的非癌症药物开发服务。

           

          类器官市场报告范围

          报告属性细节
          2022 年市场规模25.1亿美元
          2030 年的市场规模122.1亿美元
          全球复合年增长率(2022 - 2030 年)21.9%
          历史数据2020-2021
          预测期2023-2030
          涵盖的领域按器官类型
          • 胰腺
          • 其他的
          按应用
          • 生物疾病的发展
          • 传染病病理学
          • 再生医学
          • 药物研发和个性化医疗
          • 药物毒性和疗效测试
          • 其他的
          按来源
          • 多能干细胞和器官特异性成体干细胞
          按类型
          • 仪器
          • 耗材
          • 服务
          覆盖地区和国家北美
          • 我们
          • 加拿大
          • 墨西哥
          欧洲
          • 英国
          • 德国
          • 法国
          • 俄罗斯
          • 意大利
          • 欧洲其他地区
          亚太
          • 中国
          • 印度
          • 日本
          • 澳大利亚
          • 亚太其他地区
          南美洲和中美洲
          • 巴西
          • 阿根廷
          • 南美洲和中美洲其他地区
          中东和非洲
          • 南非
          • 沙特阿拉伯
          • 阿联酋
          • 中东和非洲其他地区
          市场领导者和主要公司简介
          •  
          • 干细胞技术公司
          • 赛莱斯有限公司
          • Hubrecht 类器官技术
          • 迪菲尼根
          • 类器官治疗
          • PeproTech 公司
          • 赛默飞世尔科技公司
          • 康宁公司
          • 默克公司
          • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

           

          COVID-19 影响:

          2020 年初,从事类器官市场的公司发现其产品和服务受到了轻微的不利影响,因为大多数服务提供商优先采取行动,帮助与 COVID-19 相关的消费者开展关键工作,例如提供一系列高端 COVID-19 相关的重新分配研发资源和研究工具,用于制造 SARS-Cov-2 必需产品,扩大供应链,灵活应对用于 SARS-CoV-2/COVID-19 研究的持久产品需求的扩大,并在英国、美国和中国开展 SARS-CoV-2 诊断、药物和疫苗开发的讨论和合作。COVID-19 大流行造成了意想不到的后果,导致各种疾病(包括肝脏和肾脏疾病)的诊断和治疗严重延误。

           

          竞争格局和重点公司:

          类器官市场中一些知名企业包括 STEMCELL Technologies Inc.、Hubrecht Organoid Technology、Definigen、Cellesce Ltd、Organoid Therapeutics、3Dnamics Inc.、Corning Inc.、Merck KGaA、Thermo Fisher Scientific Inc. 和 InSphero。这些领先公司专注于新产品发布和地域扩张,以满足全球消费者更高的需求,并增加其专业产品组合中的产品供应。他们的全球业务使他们能够服务于大量客户,从而扩大其市场份额。

          Organoids Market Report Scope

          Report Attribute Details
          Market size in US$ 2.51 Billion
          Market Size by US$ 12.21 Billion
          Global CAGR 21.9%
          Historical Data 2020-2021
          Forecast period 2023-2030
          Segments Covered By 器官类型(肠、肝、胃、胰腺、肺、脑、肾等)
          By 应用(生物疾病研发、传染病病理学、再生医学、药物研发及个性化医疗、药物毒性及疗效测试等)
          By 来源(多能干细胞和器官特异性成体干细胞)
          By 类型(仪器、耗材和服务)
          Regions and Countries Covered 北美(美国、加拿大、墨西哥)
          • 北美(美国、加拿大、墨西哥)
          欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
          • 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
          亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
          • 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
          南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
          • 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
          中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
          • 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
          Market leaders and key company profiles
        • STEMCELL Technologies Inc
        • Cellesce Ltd
        • Hubrecht Organoid Technology
        • Definigen
        • Organoid Therapeutics
        • PeproTech, Inc
        • Thermo Fisher Scientific Inc
        • Corning Inc
        • Merck KGaA
        • Report Coverage
          Report Coverage

          Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

          Segment Covered
          Segment Covered

          This text is related
          to segments covered.

          Regional Scope
          Regional Scope

          North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

          Country Scope
          Country Scope

          This text is related
          to country scope.

          Frequently Asked Questions


          Who are the major players in market the organoids market?

          The organoids market majorly consists of the players such as STEMCELL Technologies Inc; Cellesce Ltd; Hubrecht Organoid Technology; Definigen; Organoid Therapeutics; PeproTech, Inc; Thermo Fisher Scientific Inc; Corning Inc; Merck KGaA, and InSphero.

          What is an organoid?

          Organoid is a tiny, self-organized, three-dimensional tissue culture that is derived from stem cells. Such culture is crafted to replicate much of the complexity of an organ or to express selected aspects of it, like producing only certain types of cells. Organoids grow from stem cells—cells that can divide indefinitely and produce different types of cells as part of their progeny. Organoids can range in size from less than the width of a hair to five millimeters.

          What are the driving factors for the global organoids market across the world?

          The factors that are driving the growth of the market are growth are increasing demand for tumor modeling and biobanking, growing adoption of personalized drugs, and rising focus on developing alternatives for animal testing models propelling market growth.

          Which segment is dominating the organoids market?

          The organoids market is analyzed on the basis of organ type, application, source, and type. Based on type, the segment is divided into stomach, intestine, liver, pancreas, lung, brain, kidney, and others. The intestine segment held the largest market share in 2022, and stomach is anticipated to register the highest CAGR during the forecast period.

          The List of Companies - Organoids Market

          1. STEMCELL Technologies Inc
          2. Cellesce Ltd
          3. Hubrecht Organoid Technology
          4. Definigen
          5. Organoid Therapeutics
          6. PeproTech, Inc
          7. Thermo Fisher Scientific Inc
          8. Corning Inc
          9. Merck KGaA
          10. InSphero.

          The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

          1. Data Collection and Secondary Research:

          As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

          Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

          1. Primary Research:

          The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

          For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

          A typical research interview fulfils the following functions:

          • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
          • Validates and strengthens in-house secondary research findings
          • Develops the analysis team’s expertise and market understanding

          Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

          • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
          • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

          Below is the breakup of our primary respondents by company, designation, and region:

          Research Methodology

          Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

          1. Data Analysis:

          Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

          • Macro-Economic Factor Analysis:

          We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

          • Country Level Data:

          Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

          • Company Profile:

          The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

          • Developing Base Number:

          Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

          1. Data Triangulation and Final Review:

          The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

          We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

          We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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