Organoids Market Size, Share, Scope, and Trends by 2031
类器官市场规模预计将从 2023 年的 30.3 亿美元增至 2031 年的 150.1 亿美元。预计 2023-2031 年市场复合年增长率将达到22.3 %。类器官和器官芯片的结合很可能成为未来类器官市场的主要趋势之一。
类器官市场分析
促进类器官市场增长的因素包括对肿瘤建模和生物库的需求不断增长,以及个性化药物的采用激增。然而,缺乏熟练的专业人员和严格的安全法规阻碍了市场的增长。
类器官市场概览
类器官是从干细胞体外衍生的微观自组织 3D 结构。它们表现出其体内对应器官的各种结构和功能特征。这种多用途技术已产生许多新的人类癌症模型。现在可以从患有各种癌症的个体的肿瘤组织开始创建无限扩增的类器官。或者,基于 CRISPR 的基因修饰允许通过将任意组合的癌症基因修饰引入正常类器官来创建癌症类器官模型。肿瘤类器官与免疫细胞和成纤维细胞结合时,可产生癌症微环境模型,从而实现免疫肿瘤学应用。最近的研究强调了类器官在个性化医疗方法中的重要作用。类器官技术的不断进步使得从肿瘤活检中分离的肿瘤和以患者为中心的细胞 3D 培养成为可能。过去几十年来,已经从人类乳腺癌、膀胱癌、结肠癌、前列腺癌、胰腺癌和肝癌中产生了类器官。涉及这些模型的研究有助于清楚地概述这些恶性肿瘤。体外引入的肿瘤细胞系为一系列下游应用开辟了新途径,例如药物研发和癌症研究。此外,3D 培养比传统的 2D 癌症衍生细胞系具有更多优势。
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类器官市场:
复合年增长率(2023 - 2031)22.3%- 2023 年市场规模
30.3 亿美元 - 2031年市场规模
150.1亿美元
市场动态
- 肿瘤建模和生物样本库需求不断增长Biobanking
- 个性化药物使用率飙升
- 专注于药物研发活动
关键人物
- 干细胞技术 Technologies
- 分子设备有限责任公司
- HUB Organoids BV (Hubrecht 类器官技术)
- 定义基因
- 类器官治疗
- 赛默飞世尔科技公司;
- 康宁公司
- 默克公司
- 智能语音助手
- ACRO 生物系统公司
区域概况
- 北美
- 欧洲
- 亚太
- 南美洲和中美洲
- 中东和非洲
市场细分
- 肠
- 肝
- 胃
- 胰腺
- 肺
- 脑
- 肾
- 发育生物学疾病
- 传染病病理学
- 再生医学
- 药物毒性和疗效测试
- 药物研发和个性化医疗
- 多能干细胞
- 器官特异性成体干细胞
- 仪器
- 耗材
- 服务
- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
类器官市场驱动因素和机遇
个性化药物的普及率不断上升,利好类器官市场
个性化医疗,又称精准医疗,是一种根据预期反应或疾病风险为个体患者量身定制治疗程序或药物的医疗模式。个性化医疗联盟发表的一项研究显示,个性化医疗在 FDA 批准的新分子实体中的份额从 2005 年的 5% 上升到 2016 年的 25% 以上。此外,2022 年美国食品药品管理局 (FDA) 药品评估和研究中心 (CDER) 批准了 37 个新分子实体 (NME)。其中 12 个 NME 为个性化医疗,约占 34%。此外,生物制药公司对个性化药物的研发投入几乎翻了一番,预计到 2027 年将增加 33%。生物制药研究人员还预测未来几年个性化药物的开发将增加 69%。根据个性化医疗联盟2021年发布的报告,美国市场上的个性化药物数量从2016年的132种增长到2020年的286种。
专注于药物发现活动,为类器官市场增长创造机会
对新型和先进药物的需求不断增长,推动了药物发现和研究的整体步伐。根据 ClinicalTrials.gov 的数据,2021 年临床试验研究总数估计为 384,288 项。HUB 最近的一项调查指出,类器官可以通过识别不太可能从药物中受益的患者并将其排除在临床试验之外,从而有可能使昂贵的药物更具成本效益。全球越来越多的临床试验预计将推动对先进医疗技术的需求,包括类器官模型。药物发现中的类器官不仅限于癌症;它们还用于其他疾病研究,包括囊性纤维化、多囊肾病、小头畸形以及肠道和呼吸道感染。例如,类器官可以总结器官的特性,例如器官结构和功能。它们还可以恢复组织或器官的原始遗传和表观遗传状态,使其适合基因编辑。因此,继续关注药物发现活动以挖掘尚未开发的医学领域,为类器官市场提供了更重要的增长机会。
类器官市场报告细分分析
有助于类器官市场分析的关键部分是类型、应用、来源、类型和方法。
- 根据类型,类器官市场分为肠、肝、胃、胰腺、肺、脑、肾等。肠道部分在 2023 年占据了最大的市场份额,预计在预测期内将录得最高的复合年增长率。
- 根据应用,市场细分为发育生物学、传染病病理学、再生医学、药物毒性和疗效测试、药物发现和个性化医疗等。发育生物学疾病领域在 2023 年占据了最大的市场份额;预计在 2023-2031 年期间将实现最高的复合年增长率。
- 根据来源,类器官市场分为多能干细胞和器官特异性成体干细胞。微生物部分在 2023 年占据了更大的市场份额。预计多能干细胞部分在预测期内将实现更高的复合年增长率。
- 根据产品,类器官市场分为仪器、耗材和服务。耗材部分在 2023 年占据了最大的市场份额。
- 根据方法,类器官市场分为微图案化板、超低附着板、悬滴、微滴/乳液等。微生物部分在 2023 年占据了最大的市场份额。悬滴部分预计在预测期内将实现最高的复合年增长率。
类器官市场份额按地区分析
类器官市场报告的地理范围主要分为五个区域:北美、亚太、欧洲和中东及非洲。
北美主导着类器官市场。美国的市场参与者正专注于有机增长战略以巩固其立足点。类器官有可能克服生物医学研究中的几个先前限制,这些研究旨在获得对人类发育的机制见解、产生人类疾病的精确模型以及为再生医学产生与患者匹配的组织来源。2023 年,哈佛大学 Wyss 研究所和杜克大学的研究人员与 Gameto 合作开发了一种人类卵巢类器官,该类器官支持卵细胞成熟并为不孕症和卵巢癌等疾病带来新的治疗方法。该技术于 2022 年授权给 Gameto,并用于开发与女性生殖系统相关的疾病的治疗方法。此外,美国对类器官的研究活动有所增加。例如,辛辛那提儿童医院的干细胞和类器官医学中心 (CuSTOM) 正在利用创新的干细胞技术和类器官推进个性化再生疗法。研究的目标是设计出针对特定患者的类器官组织,用于治疗性移植。因此,由于研发活动不断增加、组织工程和器官移植需求不断增长以及类器官采用率高,预计预测期内美国对类器官的需求将增长。
类器官市场报告范围
报告属性 | 细节 |
---|---|
2023 年的市场规模 | 30.3亿美元 |
2031 年市场规模 | 150.1亿美元 |
全球复合年增长率(2023 - 2031) | 22.3% |
史料 | 2021-2022 |
预测期 | 2024-2031 |
涵盖的领域 | 按类型
|
覆盖地区和国家 | 北美
|
市场领导者和主要公司简介 |
|
- 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。
类器官市场新闻和最新发展
通过收集一手和二手研究后的定性和定量数据来评估类器官市场,其中包括重要的公司出版物、协会数据和数据库。以下列出了市场的一些发展情况:
- 加拿大政府宣布在不列颠哥伦比亚省本拿比开设 STEMCELL Technologies 新的先进工厂。这项投资使 STEMCELL Technologies 能够建造一个符合更高监管标准的新生物制造工厂。这将支持各种医疗治疗的临床试验,目的是找到治疗癌症和其他严重疾病的方法。(STEMCELL Technologies,新闻稿,2024 年 7 月)
类器官市场报告覆盖范围和交付成果
“类器官市场规模和预测(2021-2031)”报告对以下领域进行了详细的市场分析:
- 范围内涵盖的所有主要细分市场的全球、区域和国家级类器官市场规模和预测
- 类器官市场趋势以及市场动态,如驱动因素、限制因素和关键机遇
- 详细的 PEST/波特五力分析和 SWOT 分析
- 类器官市场分析涵盖主要市场趋势、全球和区域框架、主要参与者、法规和最新的市场发展。
- 行业格局和竞争分析,涵盖市场集中度、热图分析、知名参与者以及类器官市场的最新发展
- 详细的公司简介
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
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to country scope.
Frequently Asked Questions
Strategic initiatives by companies would bring attractive trends in the market in the coming years.
Factors contributing to the organoids market growth include the increasing demand for tumor modeling and biobanking, and a surging adoption of personalized drugs.
North America dominated the market in 2023.
The market is expected to register a CAGR of 22.3% during 2023–2031.
The estimated value of the market would be US$ 15.01 billion by 2031.
STEMCELL Technologies; Molecular Devices, LLC.; HUB Organoids B.V. (Hubrecht Organoid Technology); DefiniGEN; Organoid Therapeutics; Thermo Fisher Scientific Inc.; Corning Inc.; Merck KgaA; InSphero; ACRO Biosystems; and Bio-Techne Corporation are among the key players in the market.
The List of Companies - Organoids Market
- STEMCELL Technologies
- Molecular Devices, LLC.
- HUB Organoids B.V. (Hubrecht Organoid Technology)
- DefiniGEN
- Organoid Therapeutics
- Thermo Fisher Scientific Inc.
- Corning Inc.
- Merck KGaA
- InSphero
- ACRO Biosystems
- Bio-Techne Corporation.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
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Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.