骨科植入物抗菌涂层表面处理市场概况、增长、趋势、分析、研究报告(2021-2028 年)

  • Report Code : TIPRE00017477
  • Category : Medical Device
  • Status : Published
  • No. of Pages : 148
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Orthopedic Implant Antibacterial Coatings Surface Treatment Market Analysis 2028

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骨科植入物抗菌涂层表面处理市场预计将从 2021 年的 8715 万美元增至 2028 年的 1.7855 亿美元;预计 2021 年至 2028 年的复合年增长率为 10.8%。

对于接受骨科植入手术的患者来说,细菌感染和感染引起的免疫反应已成为一种威胁生命的问题。传统生物材料的生物污染会导致细菌侵入受伤部位,从而导致术后疾病。因此,迫切需要用于骨科植入物的抗感染和免疫逃避涂层。骨科医院对骨科植入物(如螺钉、板、钉和人工关节)的需求不断增加。此外,对用抗生物污染聚合物涂覆植入物的需求也在增加,这种聚合物可防止生物物质和细菌粘附在表面。

骨科植入物抗菌涂层表面处理市场按类型、材料类型和地域进行细分。按地域划分,市场大致分为北美、欧洲、亚太地区、中东和非洲以及南美和中美。该报告提供了对市场的见解和深入分析,强调了市场趋势、技术进步和市场动态等参数,以及对全球领先市场参与者的竞争格局的分析。     

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骨科植入物抗菌涂层表面处理市场:

Orthopedic Implant Antibacterial Coatings Surface Treatment Market: Strategic Insights

Orthopedic Implant Antibacterial Coatings Surface Treatment Market
  • CAGR
    CAGR (2021 - 2028)
    10.8%
  • Market Size 2021
    US$ 87.15 Million
  • Market Size 2028
    US$ 178.55 Million

Market Dynamics

GROWTH DRIVERS
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FUTURE TRENDS
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OPPORTUNITIES
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Key Players

  • DOT GmbH
  • Covalon Technologies Ltd
  • Sciessent LLC
  • Harland Medical Systems Inc
  • Isoflux Inc
  • Allvivo Vascular Inc
  • aap Implantate AG
  • BASF SE
  • Agienic Inc

Regional Overview

Regional And Country Scope
  • 北美(美国、加拿大、墨西哥)
  • 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
  • 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
  • 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
  • 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)

Market Segmentation

Segment 1类型(被动表面处理/改性(PSM)
    Segment2活性表面处理/改性
    • ASM
    Segment3围手术期局部抗菌载体或涂层
    • LCC
    Segment4材料类型(金属涂层和非金属涂层)

      骨科植入物抗菌涂层表面处理市场
      • Orthopedic Implant Antibacterial Coatings Surface Treatment Market
        复合年增长率(2021 - 2028 年)
        10.8%
      • 2021 年市场规模
        8,715 万美元
      • 2028 年市场规模
        1.7855 亿美元

      市场动态

      增长动力
      • 財政部
      • 財政部
      • 財政部
      未来的趋势
      • 財政部
      • 財政部
      • 財政部
      机会
      • 財政部
      • 財政部
      • 財政部

      关键人物;主力;重要一员

      •  
      • 交通部有限公司
      • 科瓦隆技术有限公司
      • Sciessent LLC
      • 哈兰德医疗系统公司
      • Isoflux 公司
      • Allvivo Vascular, Inc.
      • aap 植入物公司
      • 巴斯夫
      • Agienic 公司

      区域概况

      Orthopedic Implant Antibacterial Coatings Surface Treatment Market
      • 北美
      • 欧洲
      • 亚太
      • 南美洲和中美洲
      • 中东和非洲

      市场细分

      Orthopedic Implant Antibacterial Coatings Surface Treatment Market类型
      • 被动表面处理/改性
      Orthopedic Implant Antibacterial Coatings Surface Treatment Market活性表面处理/改性
      • 自动化系统工程
      Orthopedic Implant Antibacterial Coatings Surface Treatment Market围手术期局部抗菌载体或涂层
      • 低成本航空
      Orthopedic Implant Antibacterial Coatings Surface Treatment Market材料种类
      • 金属涂层和非金属涂层
      • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

       

      市场洞察

      植入物相关感染患病率上升推动骨科植入物抗菌涂层表面处理市场增长

      植入物相关感染由多种因素引起,包括抗菌预防、细菌负荷、微生物和宿主类型、手术程序和技术以及植入物类型。植入物相关感染的患病率不断上升是推动骨科植入物抗菌涂层表面处理市场发展的主要因素之一。

      例如,根据《骨科手术与研究杂志》2018年的研究报告,骨科创伤患者中植入物相关感染的患病率在5%至10%之间。美国每年有75万至100万例植入物相关感染病例,政府需要花费超过16亿美元来支付因植入物相关感染而产生的超额住院费用。尤其是随着骨科植入物的广泛使用,感染植入物的数量持续增加。即使可以通过二次手术成​​功移除受感染的植入物,肢体的功能和骨折愈合也可能受到限制,最终可能导致致命的外科手术,例如截肢、关节置换术或关节融合术。因此,植入物相关感染的高流行病学产生了对适当的植入物抗菌涂层处理的需求,这将支持市场的增长。

      由于假体关节感染(PJI)的发病率很高,对骨科植入物抗菌涂层表面处理的需求不断增加。PJI 是全关节置换术后最严重的并发症。根据《关节年鉴》2021 年发表的一篇文章,仅在美国治疗 PJI 的估计费用就高达 16.2 亿美元。PJI 的发病率因所涉及的关节而异。根据研究,全膝关节置换术、全髋关节置换术和全肩关节置换术的报告发病率分别为 0.25% 至 2%、0.5% 至 1% 和不到 1%。大约 23% 至 25% 的全膝关节置换术和 12% 至 15% 的全髋关节置换术是针对 PJI 进行的。

      此外,根据 aap Implantate AG 发布的投资者介绍,2020 年,在骨科创伤中,估计多达 30% 的病例可能导致感染。同样,骨折相关感染 (FRI) 是骨损伤后的严重并发症,可能带来严重的诊断挑战。根据德国联邦统计局 (Destatis) 的数据,2008 年至 2018 年间,FRI 的患病率从每 100,000 人 8.4 例增加到每 100,000 人 10.7 例,增幅为 0.28。因此,骨科植入物相关感染患病率的增加将增加对骨科植入物抗菌涂层表面处理的需求。

       

      抗菌涂层技术进步对骨科植入物抗菌涂层表面处理市场增长贡献巨大

      微生物定植、感染和生物膜形成是植入物使用过程中的重大并发症,也是植入物失败的主要风险因素。为了减少植入物相关的感染,抗菌材料正越来越多地被研究并应用于植入物表面。抗菌涂层技术似乎是在不影响患者护理的情况下改善医院感染控制的最有效方法。抗菌涂层的应用范围相当广泛,因为它具有防止微生物生长的功能特性。许多表面涂层技术正在研究中,从用于医疗器械和外科植入物的药用辅料和抗菌剂到确保植入物表面消毒的涂层。银以其抗菌和抗菌特性而闻名,因此被广泛用于抗菌涂层。纳米结构银是最普遍的抗菌剂,可以纳米颗粒、纳米线和纳米层的形式用于骨科植入物。二氧化钛还因其抗菌特性而闻名,这种化合物已被证明可以杀死 99.9% 的大肠杆菌菌落。亲水涂层和生物膜抑制表面技术是植入式设备中的一些最新技术。

      市场参与者越来越注重提供技术先进的医疗产品和带有抗菌涂层的骨科植入物,这将有助于预测期内的市场增长。例如,Specialty Coating Systems Inc. 提供新的 SCS microRESIST 抗菌聚对二甲苯技术,该技术可以有效消除涂层医疗设备上的有害微生物。它可以为医疗植入物涂上具有有效抗菌性能的生物相容性聚对二甲苯涂层。

      同样,总部位于德国的 DOT GmbH 公司提供骨科植入式器械物理气相沉积 (PVD) 涂层技术。PVD 涂层技术涉及使用氮气的特殊电弧蒸发技术将陶瓷硬质材料层应用于植入物。具有这种陶瓷涂层的植入物可以在很大程度上防止异物反应,并显著提高植入物表面的生物相容性。除此之外,DOT 还开发了一种名为 BONIT 的创新技术,该技术包括在骨科植入物上施加薄的可吸收磷酸钙层的电化学过程。磷酸钙用于医疗涂层技术,因为它们可确保骨组织的快速生长并促进植入物与周围组织之间高强度的连接,从而缩短愈合期。因此,抗菌涂层的这种技术进步将推动骨科植入物抗菌涂层表面处理市场的发展。

      类型洞察               

      根据类型,全球骨科植入物抗菌涂层表面处理市场细分为被动表面处理/改性 (PSM)、主动表面处理/改性 (ASM) 和围手术期抗菌局部载体或涂层 (LCC)。2020 年,主动表面处理/改性 (ASM) 细分市场占据了最大的市场份额。此外,预计同一细分市场将在 2021-2028 年期间实现最高的复合年增长率。ASM 涉及在骨科植入物表面应用药理活性抗菌剂或化合物,如抗生素、防腐剂、金属离子或有机分子。植入物表面的这种药理活性涂层可能会将植入物从被动或药理惰性的医疗器械转变为载药医疗器械。DOT GmbH 和 Harland Medical Systems, Inc. 等公司提供抗菌涂层表面处理,预计将在预测期内推动市场发展。   

      材料类型洞察

      根据材料类型,骨科植入物抗菌涂层表面处理市场分为金属涂层和非金属涂层。金属涂层部分将在 2021 年占据更大的市场份额。此外,由于低剂量水平下的高效性且不会产生抗菌耐药性,预计同一部分将在骨科植入物抗菌涂层表面处理市场中占据相当大的市场份额。金属基抗菌涂层可以为骨科植入物相关感染提供可持续的解决方案,预计将推动该部分的发展。

      产品发布和并购是全球骨科植入物抗菌涂层表面处理市场参与者高度采用的策略。以下列出了一些近期的关键市场发展:

      2021 年 9 月,aap Implantate AG 宣布,三颗采用公司创新抗菌银技术涂层的植入物已植入患者体内,以检查愈合过程。aap 解决了创伤学领域最大的、尚未充分解决的挑战之一,即手术部位感染 (SSI),因为所有三例手术的愈合过程都非常好,没有记录到任何感染迹象。总体结果对 aap 计划于 2021 年第四季度在德国启动以获得 CE 批准的计划中的人体临床研究是一个积极的迹象。


      2020 年 3 月,Covalon Technologies Ltd. 推出了突破性的抗菌技术 CovaGuard,该技术可杀死 COVID-19 病毒(或“SARS-CoV-2”)以及其他病毒、细菌和病原体,并通过长时间捕获和灭活微生物提供持续保护。CovaGuard 可安全应用于皮肤和防护医疗设备上。

      由于 COVID-19 疫情,医疗系统负担过重,向所有患者提供医疗服务已成为全球挑战。随着 COVID-19 疫情的持续蔓延,医疗器械公司发现难以管理其运营。许多提供骨科植入物抗菌涂层表面处理产品的公司在美国开展业务,其业务受到 COVID-19 疫情的不利影响。这场疫情扰乱了产品分销,并导致公司设施暂时关闭。例如,根据 2020 年 5 月发表的《英国外科杂志》,骨科手术受到的影响最大,全球有 630 万例手术因疫情而取消。此外,为了减少医院接触 COVID-19 而取消择期手术,以及将手术室改为重症监护室,这阻碍了骨科植入物抗菌涂层表面处理市场的增长。然而,随着 2021 年新的 COVID-19 病例减少以及情况逐渐好转,预计未来几天市场将会增长。

      骨科植入物抗菌涂层表面处理市场报告范围

      报告属性细节
      2021 年市场规模8,715万美元
      2028 年市场规模1.7855亿美元
      全球复合年增长率(2021 - 2028)10.8%
      历史数据2019-2020
      预测期2022-2028
      涵盖的领域按类型
      • 被动表面处理/改性
      通过主动表面处理/改性
      • 自动化系统工程
      通过手术周围抗菌局部载体或涂层
      • 低成本航空
      按材料类型
      • 金属涂层和非金属涂层
      覆盖地区和国家北美
      • 我们
      • 加拿大
      • 墨西哥
      欧洲
      • 英国
      • 德国
      • 法国
      • 俄罗斯
      • 意大利
      • 欧洲其他地区
      亚太
      • 中国
      • 印度
      • 日本
      • 澳大利亚
      • 亚太其他地区
      南美洲和中美洲
      • 巴西
      • 阿根廷
      • 南美洲和中美洲其他地区
      中东和非洲
      • 南非
      • 沙特阿拉伯
      • 阿联酋
      • 中东和非洲其他地区
      市场领导者和主要公司简介
      •  
      • 交通部有限公司
      • 科瓦隆技术有限公司
      • Sciessent LLC
      • 哈兰德医疗系统公司
      • Isoflux 公司
      • Allvivo Vascular, Inc.
      • aap 植入物公司
      • 巴斯夫
      • Agienic 公司
      • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

       

      骨科植入物抗菌涂层表面处理-市场细分

      全球骨科植入物抗菌涂层表面处理市场按类型、材料类型和地域进行细分。就产品而言,市场细分为被动表面处理/改性 (PSM)、主动表面处理/改性 (ASM) 和围手术期抗菌局部载体或涂层 (LCC)。根据材料类型,骨科植入物抗菌涂层表面处理市场细分为金属涂层和非金属涂层。就地域而言,市场大致分为北美、欧洲、亚太地区、中东和非洲以及南美和中美洲。

      公司简介

      • 交通部有限公司
      • 科瓦隆技术有限公司
      • Sciessent LLC
      • 哈兰德医疗系统公司
      • Isoflux 公司
      • Allvivo Vascular, Inc.
      • aap 植入物公司
      • 巴斯夫
      • Agienic 公司
      • 阿兰生物医学

      Orthopedic Implant Antibacterial Coatings Surface Treatment Market Report Scope

      Report Attribute Details
      Market size in US$ 87.15 Million
      Market Size by US$ 178.55 Million
      Global CAGR 10.8%
      Historical Data 2019-2020
      Forecast period 2022-2028
      Segments Covered By 类型(被动表面处理/改性(PSM)
      By 活性表面处理/改性
      • ASM
      By 围手术期局部抗菌载体或涂层
      • LCC
      By 材料类型(金属涂层和非金属涂层)
      Regions and Countries Covered 北美(美国、加拿大、墨西哥)
      • 北美(美国、加拿大、墨西哥)
      欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
      • 欧洲(英国、德国、法国、俄罗斯、意大利、欧洲其他地区)
      亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
      • 亚太地区(中国、印度、日本、澳大利亚、亚太地区其他地区)
      南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
      • 南美洲和中美洲(巴西、阿根廷、南美洲和中美洲其他地区)
      中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
      • 中东和非洲(南非、沙特阿拉伯、阿联酋、中东和非洲其他地区)
      Market leaders and key company profiles
    • DOT GmbH
    • Covalon Technologies Ltd
    • Sciessent LLC
    • Harland Medical Systems Inc
    • Isoflux Inc
    • Allvivo Vascular Inc
    • aap Implantate AG
    • BASF SE
    • Agienic Inc
    • Report Coverage
      Report Coverage

      Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

      Segment Covered
      Segment Covered

      This text is related
      to segments covered.

      Regional Scope
      Regional Scope

      North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

      Country Scope
      Country Scope

      This text is related
      to country scope.

      Frequently Asked Questions


      Which is the most influencing segment growing in the orthopedic implant antibacterial coatings surface treatment market report?

      Active Surface Finishing/Modifications (ASM) segment growing in the orthopedic implant antibacterial coatings surface treatment market.

      What are the opportunities for new orthopedic implant antibacterial coatings surface treatment market entrants?

      High market potential in developing economies is likely to fuel the market growth in the comping years.

      Which region is lucrative for the orthopedic implant antibacterial coatings surface treatment market?

      Asia-Pacific is the lucrative for the orthopedic implant antibacterial coatings surface treatment market.

      What are the key trends in the orthopedic implant antibacterial coatings surface treatment market?

      Increasing number of product launches and strategic initiatives taken by market players is likely to act as trend the market growth in the comping years.

      Which are the key players in the orthopedic implant antibacterial coatings surface treatment market?

      Key players in the market are DOT GmbH, Covalon Technologies Ltd., Sciessent LLC, Harland Medical Systems, Inc., Isoflux, Inc., Allvivo Vascular, Inc., aap Implantate AG, BASF SE, Agienic Inc., ARAN BIOMEDICAL among others.

      What are the driving factors for the orthopedic implant antibacterial coatings surface treatment market across the globe?

      Key factors driving the growth of the market are rise in prevalence of implant-associated infections and rise in prevalence of implant-associated infections drive the market growth. However, high cost of implants with antimicrobial coating hampers the market growth.

      What is orthopedic implant antibacterial coatings surface treatment?

      Among patients undergoing orthopedic implant surgery, bacterial infection and infection-induced immune responses have become a life-threatening concern. Biocontamination of conventional biomaterials causes bacterial invasion in injured areas, resulting in postoperative illness. As a result, anti-infection and immune-evasive coatings for orthopedic implants are desperately needed. Orthopedic implants such as screws, plates, nails, and artificial joints have grown in great demand by hospitals for orthopedic surgery. Coating the implants with an anti-biofouling polymer, which prevents bio substances and bacteria from adhering onto the surface, is in demand.

      The List of Companies - Orthopedic Implant Antibacterial Coatings Surface Treatment Market

      1. DOT GmbH
      2. Covalon Technologies Ltd.
      3. Sciessent LLC
      4. Harland Medical Systems, Inc.
      5. Isoflux, Inc.
      6. Allvivo Vascular, Inc.
      7. aap Implantate AG
      8. BASF SE
      9. Agienic Inc.
      10. ARAN BIOMEDICAL

      The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

      1. Data Collection and Secondary Research:

      As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

      Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

      1. Primary Research:

      The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

      For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

      A typical research interview fulfils the following functions:

      • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
      • Validates and strengthens in-house secondary research findings
      • Develops the analysis team’s expertise and market understanding

      Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

      • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
      • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

      Below is the breakup of our primary respondents by company, designation, and region:

      Research Methodology

      Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

      1. Data Analysis:

      Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

      • Macro-Economic Factor Analysis:

      We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

      • Country Level Data:

      Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

      • Company Profile:

      The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

      • Developing Base Number:

      Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

      1. Data Triangulation and Final Review:

      The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

      We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

      We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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