药代动力学服务市场规模预计将从 2023 年的 15.7987 亿美元增至 2031 年的 8.7496 亿美元。预计 2023-2031 年该市场的复合年增长率将达到 7.6%。大数据分析的日益普及可能仍是药代动力学服务市场的一个关键趋势。
药代动力学服务市场分析
药代动力学研究用于确定几个参数,例如人体等效剂量 (HED) 水平和无观察效应水平 (NOEL);这些研究还涉及进行药代动力学/药效学测试。任何临床前计划的主要重点是支持对安全有效剂量范围的分析。几项毒理学研究提供了 NOEL 数据,即药物没有表现出不良反应的最高剂量。如果缺乏临床药代动力学数据,则根据比较体表面积将该剂量水平进一步转换为 HED 水平。了解潜在候选药物的药代动力学特征在药物发现计划中起着重要作用。监管机构在推动实施药代动力学研究方面发挥着重要作用。这些研究还有助于优化为住院患者提供的药物护理服务。药代动力学模型通常用于确定药物暴露量和药物浓度,以分析最佳剂量和药物在人体内的分布。医疗保健提供者实施药代动力学研究的原理来监测药物浓度、确定某些药物的剂量、最大限度地提高预期的治疗效果并最大限度地降低毒性。因此,药代动力学研究应用范围的扩大促进了药代动力学服务市场的增长。
药代动力学服务市场概况
慢性病和传染病的发病率不断上升,药代动力学研究的应用范围不断扩大,以及将药代动力学服务外包给合同研究组织,推动了药代动力学服务市场的增长。根据世界卫生组织 (WHO) 2024 年的数据,全球约有 4.22 亿人患有糖尿病,中低收入国家占大多数,每年造成约 150 万人死亡。药代动力学研究通过分析人体内吸收、分布、代谢和消除 (ADME) 的过程,对于了解药物在患者体内的行为至关重要。
定制此报告以满足您的需求
您可以免费定制任何报告,包括本报告的部分内容、国家级分析、Excel 数据包,以及为初创企业和大学提供优惠和折扣
- 获取此报告的关键市场趋势。这个免费样品将包括数据分析,从市场趋势到估计和预测。
药代动力学服务市场驱动因素和机遇
慢性病和传染病患病率上升推动市场增长
糖尿病、癌症和自身免疫性疾病等慢性病的日益流行是全球药物开发工作的主要推动力。根据世界卫生组织 (WHO) 2024 年的数据,全球约有 4.22 亿人患有糖尿病,这些病例大多发生在中低收入国家,每年造成约 150 万人死亡。制药公司处于开发治疗各种疾病的药物的前沿。药代动力学研究对于通过分析人体内的吸收、分布、代谢和消除 (ADME) 过程来了解这些药物在患者体内的行为至关重要。药物进入体循环的吸收会影响药物到达作用部位(例如血浆)的速度和浓度。药物在体内的分布模式因其生化特性和身体生理学而异。代谢涉及身体将药物加工成后续化合物的过程。这一步骤有助于将药物转化为水溶性物质,使其适合肾脏清除。代谢对于将可待因等前体药物转化为活性代谢物也很重要。药物从体内排泄主要由肾脏控制;然而,在某些情况下,药物可能通过肺、皮肤或胃肠道排泄。ADME 动力学定义了药物在体内的生物利用度,药物的维持剂量是根据其清除时间(所需血浆浓度除以生物利用度)计算的。了解清除率可让医生计算出适当的给药率。
药代动力学研究侧重于优化受试者的药物剂量方案,以了解药物的功效和安全性。这些研究对于确保长期治疗药物的安全性至关重要,有助于评估药物制剂在慢性病管理中的适用性和稳定性。因此,慢性病和传染病负担的增加凸显了药代动力学研究对于开发安全有效的个性化治疗的重要性。
越来越多地采用体内和体外模型来了解药代动力学的变化,以推动未来几年的市场发展
收集和处理药物制造过程中产生的大量药代动力学数据是一项昂贵、繁琐且耗时的任务。这些任务的劳动和成本密集型性质凸显了对药代动力学模拟模型和体外-体内药代动力学相关模型 (IVIVC) 等模型的需求,这些模型可用于预测药代动力学参数。药代动力学模拟模型是一种使用计算和数学模型解释特定条件下生活环境中药物动力学的工具。此外,IVIVC 模型是药物发现过程的基本组成部分。在药物开发的早期阶段分析 PK/PD 预测(即药代动力学/药效学预测)对于先导优化策略以及进一步降低流失率是必要的。在开发新的体外和体内策略以改善和表征药代动力学特性方面取得了重大进展。IVIVC 模型被提议作为一种经济有效的替代方案来评估生物制药特性,以分析药物的生物利用度并确定其应用。因此,预计此类体内和体外模型将在不久的将来为药代动力学服务市场提供丰厚的机会。
药代动力学服务市场份额分析(按地区)
药代动力学服务市场报告的地理范围主要分为五个地区:北美、亚太地区、欧洲、中东和非洲以及南美和中美洲。在北美,药代动力学服务市场目前处于增长阶段并呈指数级增长。美国占北美药代动力学服务市场的最大份额。该国已成为领先的临床研究目的地;它占全球临床试验总数的约 50%。现有的医疗基础设施、快速的审批时间表和有利的监管框架为制药研究公司开展临床试验创造了有利的环境。此外,在美国进行的试验产生的数据在全球范围内被接受。根据世界卫生组织 (WHO) 的报告,美国在 2021 年登记的临床试验数量最多 (157,618)。北美国家研究和临床试验数量的增加预计将对该地区的药代动力学服务市场产生积极影响。
药代动力学服务市场区域洞察
Insight Partners 的分析师已详尽解释了预测期内影响药代动力学服务市场的区域趋势和因素。本节还讨论了北美、欧洲、亚太地区、中东和非洲以及南美和中美洲的药代动力学服务市场细分和地理分布。
- 获取药代动力学服务市场的区域特定数据
药代动力学服务市场报告范围
报告属性 | 细节 |
---|---|
2023 年的市场规模 | 15.7987亿美元 |
2031 年市场规模 | 8.7496亿美元 |
全球复合年增长率(2023 - 2031) | 7.6% |
史料 | 2021-2022 |
预测期 | 2024-2031 |
涵盖的领域 | 按药物类型
|
覆盖地区和国家 | 北美
|
市场领导者和主要公司简介 |
|
药代动力学服务市场参与者密度:了解其对业务动态的影响
药代动力学服务市场正在快速增长,这得益于终端用户需求的不断增长,这些需求源于消费者偏好的不断变化、技术进步以及对产品优势的认识不断提高等因素。随着需求的增加,企业正在扩大其产品范围,进行创新以满足消费者的需求,并利用新兴趋势,从而进一步推动市场增长。
市场参与者密度是指在特定市场或行业内运营的企业或公司的分布情况。它表明在给定市场空间中,相对于其规模或总市场价值,有多少竞争对手(市场参与者)存在。
在药代动力学服务市场运营的主要公司有:
- Charles River Laboratories International Inc.,
- Eurofins Scientific SE,
- Evotec SE,
- Certara 公司,
- Parexel 国际公司,
- 赛默飞世尔科技公司,
免责声明:上面列出的公司没有按照任何特定顺序排列。
- 获取药代动力学服务市场顶级关键参与者概述
药代动力学服务市场新闻和最新发展
药代动力学服务市场通过收集一级和二级研究后的定性和定量数据进行评估,其中包括重要的公司出版物、协会数据和数据库。下面提到了药代动力学服务市场的一些发展:
- 赛默飞世尔科技在弗吉尼亚州里士满开设了一家最先进的生物分析实验室,扩大了其临床研究业务。新部门将支持生物制药生态系统对一致、高质量实验室服务日益增长的需求,以加速药物开发。里士满生物分析实验室自 1985 年开始运营,为小分子药物、生物制剂、疫苗和生物标志物开发的所有阶段提供服务。药物测试服务包括药物 PK/PD、免疫原性和生物标志物定量,以支持药物的功效和安全性。(来源:赛默飞世尔科技,新闻稿,2022 年 10 月)
- Charles River Laboratories International, Inc. 与 Kibur Medical 合作,独家提供其可植入微型设备 (IMD),用于体内临床前肿瘤学研究。Kibur 的微型设备技术可容纳多达 20 种不同的化合物用于局部给药,这使得它能够将疗法直接注入疾病组织,从而可以对药代动力学特性尚不了解的早期化合物进行研究。(来源:Charles River Laboratories International, Inc.,通讯,2021 年 2 月)
药代动力学服务市场报告覆盖范围和交付成果
“药代动力学服务市场规模和预测(2021-2031 年)”报告对市场进行了详细分析,涵盖以下领域:
- 药代动力学服务市场规模及全球、区域和国家层面所有主要细分市场的预测
- 药代动力学服务市场趋势以及市场动态,如驱动因素、限制因素和关键机遇
- 详细的 PEST/波特五力分析和 SWOT 分析
- 药代动力学服务市场分析涵盖主要市场趋势、全球和区域框架、主要参与者、法规和最新市场发展
- 行业格局和竞争分析,涵盖市场集中度、热图分析、知名参与者以及药代动力学服务市场的最新发展
- 详细的公司简介
- Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
- PEST and SWOT Analysis
- Market Size Value / Volume - Global, Regional, Country
- Industry and Competitive Landscape
- Excel Dataset
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The market, by condition, is categorized into melasma, solar lentigines, post-inflammatory hyperpigmentation, and others. The melasma segment held the largest Pharmacokinetics Services market share in 2023. It is further anticipated to register the highest CAGR during the forecast period.
The market, by end user, is categorized into hospitals, dermatology centers, and others. The hospitals segment held the largest market share in 2023, Further, the dermatology centers segment is anticipated to register the highest CAGR during the forecast period.
By treatment type, the market is segmented into cosmeceutical, light or laser therapy, microdermabrasion, chemical peels, cryotherapy, and others. The cosmeceutical segment held the largest Pharmacokinetics Services market share in 2023. Further, the microdermabrasion segment is anticipated to register the highest CAGR during the forecast period.
The Pharmacokinetics Services market was valued at US$ 6,676.23 million in 2023.
The Pharmacokinetics Services market is expected to be valued at US$ 11,788.50 million in 2030.
The Pharmacokinetics Services market majorly consists of the players, including Charles River Laboratories International Inc., Eurofins Scientific SE, Evotec SE, Certara Inc., Parexel International Corp, Thermo Fisher Scientific Inc., Allucent, PACIFIC BIOLABS, SGS SA, and Shanghai Medicilon Inc..
Factors such as the rising prevalence of chronic and infectious diseases, the expanding range of applications of pharmacokinetic studies, and the outsourcing of pharmacokinetics services to contract research organizations propel the market growth. However, the limited reach of pharmacokinetics service providers in emerging countries impedes the growth of the market.
Pharmacokinetics is the study of how the body absorbs, distributes, metabolizes, and excretes drugs. It is a crucial aspect of drug development as it helps determine the dosage, timing, and route of administration of a drug to achieve the desired therapeutic effect. Pharmacokinetic services include Data Management, Programming, and CDISC Dataset Creation, Noncompartmental PK Analysis (NCA), Population Pharmacokinetics (popPK), Analysis Plans, Dosing Simulations, Comprehensive Submission-Ready Packages for Regulatory Authorities, Designing and Interpreting Nonclinical and Clinical ADME Studies, and Bioanalytical Method Validation, Reports, and Compendial Analytical Methods.
Trends and growth analysis reports related to Life Sciences : READ MORE..
The List of Companies - Pharmacokinetics Services Market
- Charles River Laboratories International Inc.
- Eurofins Scientific SE
- Evotec SE
- Certara Inc.
- Parexel International Corp
- Thermo Fisher Scientific Inc.
- Allucent
- PACIFIC BIOLABS
- SGS SA
- Shanghai Medicilon Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.