Sialorrhea Treatment Market Growth Report | Size, Share & Forecast Analysis 2030
市场洞察和分析师观点:
流涎是指唾液分泌过多。当个体后部唾液大量渗漏到气管而不是被常规吞咽时,称为后流涎。受前流涎影响的患者会出现过多的前部或前部唾液(也称为流口水)流到脸上和衣服上,这使他们难以保持卫生、护理皮肤以及与他人互动。误吸是由此引起的长期肺部刺激,有时会导致肺炎。
增长动力和挑战:
患有神经系统疾病的患者患慢性流涎的机会较高。流涎通常通过长期神经系统疾病引起的症状来治疗,这增加了患者的总体负担。患者的身体和心理负担会对他们的生活质量产生负面影响。患有脑瘫、帕金森病、中风或 ALS 等神经系统疾病的人主要受到慢性流涎的影响。这些疾病会损害吞咽和唾液管理所需的肌肉协调性。神经损伤或退化是 ALS 或帕金森病的结果。大脑、唾液腺和吞咽肌是这些神经的主要信号传感器。损伤导致信号中断、吞咽困难和唾液腺协调。根据《临床神经科学杂志》发表的一篇文章,2019 年,约 40% 的脑瘫儿童和 80% 的帕金森病成人患有流涎症。上述因素推动了流涎治疗市场的增长。
药物治疗的不良反应是药物中枢作用引起的刺激、烦躁、镇静和谵妄。对于已经饱受便秘困扰的人群来说,胃肠道(GI)运动的抑制会导致便秘恶化。畏光、尿潴留和面部潮红是药物的其他副作用。
报告细分和范围:
流涎治疗市场根据药物治疗和最终用户分为两部分。按医疗治疗,市场分为药物治疗、放射治疗等。按最终用户划分,流涎治疗市场分为医院、专科诊所、家庭护理机构等。流涎治疗市场根据地理位置分为北美(美国、加拿大和墨西哥)、欧洲(法国、德国、意大利、英国、西班牙和欧洲其他地区)、亚太地区(澳大利亚、中国) 、日本、印度、韩国和亚太地区其他地区)、中东和非洲(沙特阿拉伯、阿联酋、南非以及中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷)以及南美洲和中美洲其他地区)
细分分析:
根据药物治疗,流涎治疗市场分为药物治疗、放射治疗等。 2022年,药物治疗领域占据最大的市场份额。此外,预计该细分市场在 2022 年至 2030 年期间将创下最高复合年增长率。疫苗提供针对特定传染病的主动获得性免疫力。在多项独立临床试验中,苯托品、格隆溴铵、东莨菪碱和肉毒杆菌毒素等药物治疗已被证明可有效控制流涎。药物通过口服或肠胃外给药。在解剖学外部触诊或超声检查的引导下将肉毒杆菌毒素注射到唾液腺中。
按最终用户划分,流涎治疗市场分为医院、专科诊所、家庭护理机构等。医院细分市场在 2022 年占据最大市场份额,预计 2022 年至 2030 年复合年增长率最高。流涎的治疗是在医院通过适当的治疗和运动疗法进行,并在经验丰富的跨学科医学专家(包括物理治疗师和神经病学专家)的帮助下进行。
流涎治疗市场,按药物治疗 – 2022 年和 2030 年
区域分析:
按地区划分,流涎治疗市场分为五个主要地区:北美、欧洲、亚太地区、南美洲和中美洲以及中东和非洲。对北美市场的分析主要集中在三个主要国家——美国、加拿大和墨西哥。预计 2022 年至 2030 年,亚太地区流涎治疗市场的复合年增长率将达到最高。政府不断采取举措提高人们对这种情况的认识,增加该地区的研发活动,不断增长的市场参与者转向提供更好的治疗选择,这些都是推动流涎治疗市场增长的突出因素。
流涎治疗市场机会:< br>用于流涎治疗的简易治愈性基因疗法将在预测期内为流涎治疗市场提供利润丰厚的机会
根据 NIH 的说法,一项实验性试验表明,可以在人类唾液腺中安全地进行基因治疗。该基因帮助唾液腺细胞将唾液分泌到口腔中。 Ad5 介导的 N-myc 下游调节基因 2 (NDRG2) 的转移可纠正唾液功能低下。此外,NDRG2 基因转移的使用在临床上可能对患有唾液功能低下且不想冒雌激素补充疗法副作用的绝经后妇女有用。因此,上述因素预计将为未来几年的流涎治疗市场提供机会。
竞争格局和主要公司:
Pfizer Inc、F. Hoffmann-La Roche Ltd、Mylan NV、Fresenius Kabi AG、Hikma Pharmaceuticals PLC、Novartis AG、Teva Pharmaceutical Industries Ltd.、Bristol Myers Squibb Company、GSK Plc .、拜耳股份公司和太阳制药工业有限公司是全球流涎治疗市场的知名参与者。这些公司专注于新技术的开发、现有产品的进步以及地理足迹的扩大,以满足全球不断增长的消费者需求,并扩大其专业产品组合的产品范围。在全球流涎治疗市场运营的公司正在实施各种无机和有机策略。其中一些如下:
2021 年 8 月,Merz 集团旗下企业、神经毒素领域的领导者 Merz Therapeutics 获得使用 XEOMIN 用于儿童和青少年慢性流涎的对症治疗年龄 2 至 17 岁,体重 ≥ 12 kg,因欧盟水平的神经发育障碍/神经系统疾病。美国食品和药物管理局于2020年12月批准,俄罗斯联邦医疗保健监督局于2021年8月批准。2023年2月,专门生产儿童药品的制药公司Proveca Pharma Ltd向儿童提供了Sialanar(格隆溴铵)在法国因慢性神经系统疾病而患有严重的流涎症。
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Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
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Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
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Frequently Asked Questions
The term "hypersalivation," or "sialorrhea," refers to excessive saliva production. When individuals have extensive posterior saliva leakage down their tracheas instead of being routinely swallowed, it is known as posterior sialorrhea. Patients with anterior sialorrhea experience excessive anterior or forward salivation, also known as drooling, onto their faces and clothing, which makes it difficult for them to maintain hygiene, take care of their skin, and interact with others. Aspiration, a long-term lung irritation caused by this, can occasionally lead to pneumonia.
Based on medical therapy, the pharmacologic therapy segment took the forefront leaders in the worldwide market by accounting largest share in 2022 and is expected to continue to do so till the forecast period.
Increasing prevalence of neurodegenerative disorders and various treatment options available for sialorrhea treatment are the most significant factors responsible for the overall market growth.
Pfizer Inc, F. Hoffmann-La Roche Ltd, Mylan N.V., Fresenius Kabi AG, Hikma Pharmaceuticals PLC, Novartis AG, Teva Pharmaceutical Industries Ltd., Bristol Myers Squibb Company, GSK Plc., Bayer AG, and Sun Pharmaceutical Industries Ltd among others are among the leading companies operating in the sialorrhea treatment market.
Sialorrhea treatment market is segmented by regions comprising of North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America.
The hospitals segment dominated the sialorrhea treatment market and accounted for the largest market share in 2022.
The List of Companies - Sialorrhea Treatment Market
- Pfizer Inc
- F. Hoffmann-La Roche Ltd
- Mylan N.V.
- Fresenius Kabi AG
- Hikma Pharmaceuticals PLC
- Novartis AG
- Teva Pharmaceutical Industries Ltd.
- Bristol Myers Squibb Company
- GSK Plc.
- Bayer AG
- Sun Pharmaceutical Industries Ltd
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
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- Validates and strengthens in-house secondary research findings
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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
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Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
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We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
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- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.