小分子药物发现市场策略、顶级参与者、增长机会、2031 年分析和预测

  • Report Code : TIPRE00004774
  • Category : Life Sciences
  • Status : Published
  • No. of Pages : 140
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小分子药物研发市场规模预计将从 2023 年的 509.3 亿美元增至 2031 年的 1067.7 亿美元。预计 2023-2031 年期间该市场的复合年增长率将达到 9.7%。人工智能在药物研发中的日益普及可能会成为市场未来的趋势。

小分子药物研发市场分析

小分子药物发现市场的主要推动因素是制药和生物技术公司在发现新药方面的研发力度不断加大、政府举措以及癌症的流行。其他推动市场扩张的因素包括临床试验的全球化、相关技术的快速发展以及对开展临床试验的 CRO 的需求增加。此外,小分子药物研发管线的增加也为小分子药物发现市场的增长提供了机遇。

小分子药物研发市场概况

预计亚太地区在预测期内的复合年增长率最高。技术进步的激增、亚洲和西方国家之间(为发展基因组研究)合作的激增、DNA测序价格的下降以及遗传疾病和其他目标疾病的患病率上升,正在推动亚太地区小分子药物发现市场的发展。由于 GDP 的增长导致制药行业的增长,预计亚太地区的市场将蓬勃发展。此外,可支配收入的增加也推动了先进医疗技术的采用。因此,由于上述因素,小分子药物发现市场具有巨大的潜力。

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小分子药物研发市场:

小分子药物研发市场
  • Small Molecule Drug Discovery Market
    复合年增长率(2023 - 2031)
    9.7%
  • 2023 年市场规模
    509.3 亿美元
  • 2031年市场规模
    1067.7亿美元

市场动态

增长动力
  • 蓬勃发展的医药产业
未来趋势
  • 人工智能在药物研发中的应用日益广泛
机会
  • 增加基于小分子的管道

关键参与者

  • 百时美施贵宝公司
  • 默克公司
  • 葛兰素史克公司
  • 勃林格殷格翰国际有限公司
  • 赛默飞世尔科技公司
  • ICON 股份有限公司
  • 丹纳赫公司
  • 查尔斯河实验室国际公司
  • 肿瘤设计服务
  • Revvity公司

区域概况

Small Molecule Drug Discovery Market
  • 北美
  • 欧洲
  • 亚太
  • 南美洲和中美洲
  • 中东和非洲

市场细分

Small Molecule Drug Discovery Market治疗领域
  • 肿瘤学
  • 中枢神经系统
  • 心血管
  • 呼吸系统
  • 骨科
  • 免疫学
  • 罕见疾病
  • 其他治疗领域
Small Molecule Drug Discovery Market流程/阶段
  • 目标发现
  • 目标验证
  • 潜在客户生成和提炼
  • 临床前开发
  • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

小分子药物研发市场的驱动因素和机遇

制药业蓬勃发展,研发活动激增

制药业是全球研发最密集的行业之一。人们正在努力提高效率和效力,以满足患者的需求。药品成本一直是制药公司最关心的问题,因为他们依靠研发活动来实现预期的成本目标。在过去十年中,每年批准的新型小分子药物数量急剧增加。美国食品药品管理局 (FDA) 在 2023 年批准了 55 种新药。小分子在 2023 年的新药批准中占据主导地位,占所有获批新分子实体 (NME) 的 62%。在全球范围内,美国是研发投资领先的国家,过去十年中,美国生产了全球 50% 以上的新分子。由于小分子药物具有治疗多种严重疾病的潜力,批准数量的增加导致公司对小分子药物开发的投资不断增加。

 

主要制药公司的研发投入

公司

2022 年(十亿美元)

2023年(十亿美元)

武田药品工业株式会社

4.2

5.08

辉瑞公司

11.4

10.6

基立福公司

427.05

432.71

注:呈现货币时考虑的是当前兑换率。

资料来源:年度报告和 Insight Partners 分析

研发支出对于公司发现、检查和生产新产品、支付预付款、改善现有成果以及在上市前证明产品功效和法规遵从性至关重要。这些投资因药物发现的需求和要求而异。成本包括材料、使用的耗材和员工工资,以及开发质量控制的成本。根据 PhRMA 会员公司 2021 年报告,按收入计算,排名前 15 的制药公司累计在研发上投资了 1330 亿美元,其中约 44% 的总研发投资用于药物发现。因此,公司不断增加的研发投资正在推动小分子药物发现市场的增长。

增加小分子药物研发管线,为市场增长提供机会

制药行业不断发展,治疗各种慢性疾病始终需要新的创新治疗方法。过去五年来,小分子药物的获批数量不断增加,因为它们对多种疾病均有效。小分子候选药物的研发管线正在不断壮大,可用于多种治疗应用,包括肿瘤学、高血压、糖尿病和炎症性疾病。许多大大小小的制药公司都在致力于开发多种小分子药物。

用于各种适应症的小分子药物的不断增加反过来又推动了整个行业的药物研发活动。

化合物名称

化合物类型

公司名称

临床阶段

指征

PF-06821497

小分子

辉瑞公司

第 1 阶段

癌症

PF-06873600

小分子

辉瑞公司

第 1 阶段

转移性乳腺癌

PF-06939999

小分子

辉瑞公司

第 1 阶段

实体肿瘤

PF-06952229

小分子

辉瑞公司

第 1 阶段

癌症

PF-06826647

小分子

辉瑞公司

第 1 阶段

溃疡性结肠炎

PF-07038124

小分子

辉瑞公司

第 1 阶段

特应性皮炎

PF-06842874

小分子

辉瑞公司

第 1 阶段

肺动脉高压

PF-06865571

小分子

辉瑞公司

第 1 阶段

伴有肝纤维化的非酒精性脂肪性肝炎 (NASH)

PF-06882961

小分子

辉瑞公司

第 1 阶段

2 型糖尿病、肥胖症

PF-07081532

小分子

辉瑞公司

第 1 阶段

2 型糖尿病、肥胖症

R835

小分子

Rigel 制药公司

第 1 阶段

炎症

疾病

R552

小分子

Rigel 制药公司

第 1 阶段

炎症

疾病

SY-1425

小分子

Syros Pharmaceuticals, Inc.

第 2 阶段

反洗钱

来源:公司新闻及 The Insight Partner 分析

小分子药物研发市场报告细分分析

有助于得出小分子药物发现市场分析的关键部分是治疗领域和过程/阶段。

  • 根据治疗领域,小分子药物发现市场细分为肿瘤学、中枢神经系统、心血管、呼吸、骨科、免疫学、罕见疾病和其他治疗领域。肿瘤学领域在 2023 年占据了最大的市场份额。
  • 根据流程/阶段,市场细分为目标发现、目标验证、潜在客户生成和细化以及临床前开发。潜在客户生成和细化细分市场在 2023 年占据了市场主导地位。

小分子药物研发市场份额按地区分析

小分子药物发现市场报告的地理范围主要分为五个地区:北美、亚太地区、欧洲、南美和中美洲以及中东和非洲。就收入而言,北美在 2023 年占据了市场主导地位。制药和生物技术公司在发现新药方面的研发力度加大、对药品的投资不断增加以及癌症的流行是预计将加速北美小分子药物发现市场增长的因素之一。美国是小分子药物发现规模最大、增长最快的市场。心血管疾病和癌症等慢性病的发病率不断上升是推动该国市场增长的主要动力。根据美国癌症协会的数据,到 2024 年,预计美国将有约 200 万人患上新的癌症病例,预计死亡病例将达到约 611,000 例。由于这种情况,美国卫生系统见证了对新型药物分子研发的巨额投资。此外,强大的药物渠道以及小分子药物治疗领域的批准预计将推动区域市场的发展。除了获批药物数量增加外,人们对先进疗法的认识不断提高,也可能是预测期内小分子药物发现市场增长的原因。

小分子药物发现市场报告范围

报告属性细节
2023 年的市场规模509.3亿美元
2031 年市场规模1067.7亿美元
全球复合年增长率(2023 - 2031)9.7%
史料2021-2022
预测期2023-2031
涵盖的领域按治疗领域
  • 肿瘤学
  • 中枢神经系统
  • 心血管
  • 呼吸系统
  • 骨科
  • 免疫学
  • 罕见疾病
  • 其他治疗领域
按流程/阶段
  • 目标发现
  • 目标验证
  • 潜在客户生成和提炼
  • 临床前开发
覆盖地区和国家北美
  • 我们
  • 加拿大
  • 墨西哥
欧洲
  • 英国
  • 德国
  • 法国
  • 俄罗斯
  • 意大利
  • 欧洲其他地区
亚太
  • 中国
  • 印度
  • 日本
  • 澳大利亚
  • 亚太其他地区
南美洲和中美洲
  • 巴西
  • 阿根廷
  • 南美洲和中美洲其他地区
中东和非洲
  • 南非
  • 沙特阿拉伯
  • 阿联酋
  • 中东和非洲其他地区
市场领导者和主要公司简介
  • 百时美施贵宝公司
  • 默克公司
  • 葛兰素史克公司
  • 勃林格殷格翰国际有限公司
  • 赛默飞世尔科技公司
  • ICON 股份有限公司
  • 丹纳赫公司
  • 查尔斯河实验室国际公司
  • 肿瘤设计服务
  • Revvity公司
  • 示例 PDF 通过定性和定量分析展示了内容结构和信息的性质。

小分子药物研发市场新闻及最新进展

小分子药物发现市场通过收集一级和二级研究后的定性和定量数据进行评估,其中包括重要的公司出版物、协会数据和数据库。以下列出了市场中的一些发展情况:

  • Oncodesign Services (ODS) 收购了 ZoBio,这是一家荷兰生物物理学小分子药物发现 CRO 专家。此次收购使 ODS 能够加强和扩展其在小分子发现领域的专业知识和能力,从而提供全面集成的产品,以支持其客户从靶标验证到候选药物选择的创新项目。(来源:Oncodesign Services,公司网站,2024 年 1 月)
  • 默克公司达成了新的战略药物发现合作,旨在利用强大的人工智能 (AI) 驱动的设计和发现能力,进一步推进公司的研究工作。BenevolentAI(英国伦敦)和 Exscientia(英国牛津)的合作预计将在肿瘤学、神经病学和免疫学等关键治疗领域产生几种具有一流和一流潜力的新型临床开发候选药物。(来源:默克公司,公司网站,2023 年 9 月)

小分子药物发现市场报告覆盖范围和交付成果

“小分子药物发现市场规模和预测(2021-2031)”报告对以下领域进行了详细的市场分析:

  • 范围内涵盖的所有主要细分市场的小分子药物发现市场规模和全球、区域和国家层面的预测
  • 小分子药物研发市场趋势,以及驱动因素、限制因素和关键机遇等市场动态
  • 详细的 PEST 和 SWOT 分析
  • 小分子药物发现市场分析涵盖主要市场趋势、全球和区域框架、主要参与者、法规和最新市场发展
  • 行业格局和竞争分析,涵盖市场集中度、热图分析、知名参与者以及小分子药物发现市场的最新发展
  • 详细的公司简介
  • Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
  • PEST and SWOT Analysis
  • Market Size Value / Volume - Global, Regional, Country
  • Industry and Competitive Landscape
  • Excel Dataset
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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to country scope.

Frequently Asked Questions


What is the expected CAGR of the small molecule drug discovery market?

The market is expected to register a CAGR of 9.7% during 2023–2031.

What would be the estimated value of the small molecule drug discovery market by 2031?

The small molecule drug discovery market value is expected to reach US$ 106.77 billion by 2031.

Which are the leading players operating in the small molecule drug discovery market?

Bristol-Myers Squibb Co, Merck KGaA, GSK Plc, Boehringer Ingelheim International GmbH, Thermo Fisher Scientific Inc, ICON Plc, Danaher Corp, Charles River Laboratories International Inc, Oncodesign Services, and Revvity Inc are among the key players in the market.

What are the future trends of the small molecule drug discovery market?

The growing adoption of artificial intelligence in drug discovery is expected to be a prime trend in the market in the coming years.

What are the driving factors impacting the small molecule drug discovery market?

The flourishing pharmaceutical industry with a surge in R&D activities and the growing inclination toward outsourcing are among the most significant factors fueling the market growth.

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The List of Companies - Small Molecule Drug Discovery Market

  1. Bristol-Myers Squibb Co
  2. Merck KGaA
  3. GSK Plc
  4. Boehringer Ingelheim International GmbH
  5. Thermo Fisher Scientific Inc
  6. ICON Plc
  7. Danaher Corp
  8. Charles River Laboratories International Inc
  9. Oncodesign Services
  10. Revvity Inc

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.